Sa1065 Irritable Bowel Syndrome With Constipation (IBS-C), Chronic Idiopathic Constipation (CIC), Functional Dyspepsia (FD), and Gastroesophageal Reflux Disease (GERD) Commonly Overlap: Results of a Cross-Sectional Population-Based Survey

2014 ◽  
Vol 146 (5) ◽  
pp. S-189-S-190
Author(s):  
Nimish Vakil ◽  
Marjorie Stelwagon ◽  
Elizabeth Shea ◽  
Stephen Miller
2021 ◽  
Vol 2021 (2) ◽  
pp. 68-71
Author(s):  
R.I. Khalafova ◽  

To study the frequency of detection of combinations of the main syndromes of the gastrointestinal tract (GIT) and their differential diagnosis, consisting of irritable bowel syndrome (IBS), syndrome of functional dyspepsia (SFD), chronic idiopathic dyspepsia (CIT) and gastroesophageal reflux disease (GERD). The main gastrointestinal syndromes are quite often detected among different groups of military personnel and members of their families. ES plays an important role in their formation. International recommendations allow anamnestic diagnosis of each of the syndromes in separately and in combination with each other. The medical appealability of patients depends on the severity of the symptoms of the syndromes, it is most pronounced when they are combined.


Author(s):  
Bader Saad Alahmari ◽  
Yahya Mohammed Al Allush ◽  
Moyed Hamoud Almontasheri ◽  
Saad Ali Al Zulfah ◽  
Yahya Ali Al-Imamah ◽  
...  

Evidence shows that a degree of overlap is detected between gastroesophageal reflux disease (GERD) and irritable bowel syndrome (IBS). In this review, we aim to update the current evidence from recent studies published in the last decade. Electronic and manual search strategies were both conducted to look for studies that reported the association between gastroesophageal reflux disease and IBS from 2011 to January 2021. We have included all study designs to formulate updated evidence and report all the potential outcome measures. We included a total of 16 studies on a total of 146,156 patients, collectively. Out of these studies, 14 were cross-sectional while only two were randomized controlled trials. The frequency of overlap was hugely variable among the results of the included studies, ranging between 1.7 and 74.7%. Almost all studies used the Rome III criteria for IBS and used questionnaire-based assessment for gastroesophageal reflux disease patients. Female gender and cigarette smoking were the commonest most significant risk factors for developing the overlap. Intestinal hypersensitivity, hyperactive gastric acids, and generalized abnormal motility of the digestive tract were the commonest theories. Obtained evidence remains strong, indicating the overlap between IBS and gastroesophageal reflux disease patients, however, the definite explanation remains non-clear and further studies are needed. 


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