Fabrication of Microneedle Mimicking Mosquito Proboscis Using Nanoscale 3D Laser Lithography System

2015 ◽  
Vol 9 (6) ◽  
pp. 655-661 ◽  
Author(s):  
Masato Suzuki ◽  
◽  
Takahiro Sawa ◽  
Tomokazu Takahashi ◽  
Seiji Aoyagi
Keyword(s):  
Blood Vessel ◽  
Three Dimensional ◽  
Hollow Structure ◽  
Capillary Blood ◽  
Maximum Length ◽  
Minimum Length ◽  
Laser Lithography ◽  
Capillary Blood Vessel ◽  
Lithography System

A mosquito’s proboscis, which is used for sucking blood, consists of seven complicated parts. For example, the labrum has a hollow structure, and the maxillae have micrometer-sized tooth like projections on its tip. In this study, microneedles imitating one labium and two maxillae were fabricated using a precision three-dimensional laser lithography system “Nanoscribe.” The maximum length of the fabricated microneedle was 2.0 mm, the minimum length required to reach human capillary blood vessel underneath the epidermis.

An Ultrastructural Study of Pericytes

1968 ◽  
Vol 26 ◽  
pp. 66-67
Author(s):  
T. M. Murad ◽  
E. von Haam
Keyword(s):  
Plasma Membrane ◽  
Endothelial Cell ◽  
Basement Membrane ◽  
Blood Vessel ◽  
Vascular Endothelial Cells ◽  
Myoepithelial Cells ◽  
Capillary Blood ◽  
The Body ◽  
Capillary Blood Vessel ◽  
Outer Plasma Membrane

Pericytes are vascular satellites present around capillary blood vessels and small venules. They have been observed in almost every tissue of the body and are thought to be related to vascular smooth muscle cells. Morphologically pericytes have great similarity to vascular endothelial cells and also slightly resemble myoepithelial cells.The present study describes the ultrastructural morphology of pericytes in normal breast tissue and in benign tumor of the breast. The study showed that pericytes are ovoid or elongated cells separated from the endothelial cell of the capillary blood vessel by the basement membrane of endothelial cell. The nuclei of pericytes are often very distinctive. Although some are round, oval, or elongated, others show marked irregularity and infolding of the nuclear membrane. The cytoplasm shows mono-or bipolar extension in which the cytoplasmic organelles are located (Fig. 1). These cytoplasmic extensions embrace the capillary blood vessel incompletely. The plasma membrane exhibits multiple areas of focal condensation called hemidesmosomes (Fig. 2, arrow). A variable number of pinocytotic vesicles are frequently seen lining the outer plasma membrane. Normally pericytes are surrounded by a basement membrane which is found more consistently on the outer plasma membrane separating the pericytes from the stromal connective tissue.

Occurrence of eddy flow in the flowing plasma space in capillary blood vessel of frog web

1978 ◽  
Vol 34 (7) ◽  
pp. 857-858 ◽  
Author(s):  
T. Koyama ◽  
H. Mishina ◽  
T. Asakura ◽  
D. F. Bruley
Keyword(s):  
Blood Vessel ◽  
Capillary Blood ◽  
Flowing Plasma ◽  
Capillary Blood Vessel ◽  
Eddy Flow
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