scholarly journals A comparison of non-intubated video-assisted thoracic surgery with spontaneous ventilation and intubated video-assisted thoracic surgery: a meta-analysis based on 14 randomized controlled trials

2021 ◽  
Vol 13 (3) ◽  
pp. 1624-1640
Author(s):  
Xi-Xuan Zhang ◽  
Chun-Tao Song ◽  
Zhen Gao ◽  
Bin Zhou ◽  
Hai-Bo Wang ◽  
...  
2020 ◽  
Vol 30 (4) ◽  
pp. 573-581
Author(s):  
Luca Spiezia ◽  
Aaron Liew ◽  
Elena Campello ◽  
Guido Di Gregorio ◽  
Andrea Zuin ◽  
...  

Abstract OBJECTIVES There is no consensus on the risk of thrombotic events following video-assisted thoracoscopic surgery (VATS) versus open thoracotomy (OT), despite multiple studies. In fact, the estimates for the overall thrombotic risk for VATS versus OT are inconclusive. In this systematic review and meta-analysis, we endeavoured to ascertain the best estimate of thrombotic risk in VATS versus OT. METHODS Relevant studies were searched through PubMed and Cochrane Library database. Outcomes of interests were myocardial infarction (MI), pulmonary embolism (PE) and deep vein thrombosis (DVT). Data were pooled using random-effects model. The results were presented as odds ratio (OR) with the corresponding 95% confidence interval (CI). RESULTS Nineteen studies were meta-analysed: 17 observational studies and 2 randomized controlled trials. Using propensity-matched data, in comparison with OT, VATS was associated with a statistically significant, postoperative reduction in MI (OR 0.60, 95% CI 0.39–0.91; P = 0.017), DVT/PE (OR 0.52, 95% CI 0.44–0.61; P < 0.001), PE (OR 0.59, 95% CI 0.43–0.82; P = 0.001) and DVT (OR 0.47, 95% CI 0.35–0.64; P < 0.001). Unadjusted data showed no statistical differences for all outcomes. The risk of DVT/PE (OR 0.55, 95% CI 0.42–0.72; P < 0.001), but not the other outcomes, remained significantly lower following the exclusion of the sole large study. There is no significant statistical heterogeneity between the included studies. CONCLUSIONS Overall, the postoperative thrombotic risk following VATS is significantly lower than OT. Further prospective randomized controlled trials with large sample sizes are warranted to corroborate our findings.


PLoS ONE ◽  
2016 ◽  
Vol 11 (5) ◽  
pp. e0155184 ◽  
Author(s):  
Wenxiong Zhang ◽  
Dongliang Yu ◽  
Han Jiang ◽  
Jianjun Xu ◽  
Yiping Wei

2020 ◽  
Vol 146 (12) ◽  
pp. 1117-1145
Author(s):  
Kathryn R. Fox ◽  
Xieyining Huang ◽  
Eleonora M. Guzmán ◽  
Kensie M. Funsch ◽  
Christine B. Cha ◽  
...  

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