scholarly journals Effects of pulsatile minimal invasive extracorporeal circulation on fibrinolysis and organ protection in adult cardiac surgery—a prospective randomized trial

2019 ◽  
Vol 11 (S10) ◽  
pp. S1453-S1463
Author(s):  
Angelika Graßler ◽  
Robert Bauernschmitt ◽  
Irene Guthoff ◽  
Andreas Kunert ◽  
Markus Hoenicka ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Randomized Trial ◽  
Extracorporeal Circulation ◽  
Minimal Invasive ◽  
Prospective Randomized Trial ◽  
Organ Protection ◽  
Adult Cardiac Surgery

scholarly journals The use of del Nido cardioplegia in adult cardiac surgery: A prospective randomized trial

2018 ◽  
Vol 155 (3) ◽  
pp. 1011-1018 ◽  
Author(s):  
Niv Ad ◽  
Sari D. Holmes ◽  
Paul S. Massimiano ◽  
Anthony J. Rongione ◽  
Lisa M. Fornaresio ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Randomized Trial ◽  
Prospective Randomized Trial ◽  
Adult Cardiac Surgery

Monitoring dynamic arterial elastance as a means of decreasing the duration of norepinephrine treatment in vasoplegic syndrome following cardiac surgery: a prospective, randomized trial

2017 ◽  
Vol 43 (5) ◽  
pp. 643-651 ◽  
Author(s):  
Pierre-Grégoire Guinot ◽  
Osama Abou-Arab ◽  
Mathieu Guilbart ◽  
Stéphane Bar ◽  
Elie Zogheib ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Randomized Trial ◽  
Prospective Randomized Trial ◽  
Arterial Elastance ◽  
Vasoplegic Syndrome

Minimal invasive extracorporeal circulation preserves platelet function after cardiac surgery: a prospective observational study

Perfusion ◽  
2019 ◽  
Vol 35 (2) ◽  
pp. 138-144
Author(s):  
Helena Argiriadou ◽  
Polychronis Antonitsis ◽  
Anna Gkiouliava ◽  
Evangelia Papapostolou ◽  
Apostolos Deliopoulos ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Cardiopulmonary Bypass ◽  
Correlation Coefficient ◽  
Platelet Function ◽  
Extracorporeal Circulation ◽  
Point Of Care ◽  
Postoperative Bleeding ◽  
Minimal Invasive ◽  
Elective Cardiac Surgery ◽  
Impedance Aggregometry

Introduction: Cardiac surgery on conventional cardiopulmonary bypass induces a combination of thrombocytopenia and platelet dysfunction which is strongly related to postoperative bleeding. Minimal invasive extracorporeal circulation has been shown to preserve coagulation integrity, though effect on platelet function remains unclear. We aimed to prospectively investigate perioperative platelet function in a series of patients undergoing cardiac surgery on minimal invasive extracorporeal circulation using point-of-care testing. Methods: A total of 57 patients undergoing elective cardiac surgery on minimal invasive extracorporeal circulation were prospectively recruited. Anticoagulation strategy was based on individualized heparin management and heparin level–guided protamine titration performed in all patients with a specialized point-of-care device (Hemostasis Management System – HMS Plus; Medtronic, Minneapolis, MN, USA). Platelet function was evaluated with impedance aggregometry using the ROTEM platelet (TEM International GmbH, Munich, Germany). ADPtest and TRAPtest values were assessed before surgery and after cardiopulmonary bypass. Results: ADPtest value was preserved during surgery on minimal invasive extracorporeal circulation (58.2 ± 20 U vs. 53.6 ± 21 U; p = 0.1), while TRAPtest was found significantly increased (90 ± 27 U vs. 103 ± 38 U; p = 0.03). Postoperative ADPtest and TRAPtest values were inversely related to postoperative bleeding (correlation coefficient: −0.29; p = 0.03 for ADPtest and correlation coefficient: −0.28; p = 0.04 for TRAPtest). The preoperative use of P2Y12 inhibitors was identified as the only independent predictor of a low postoperative ADPtest value (OR = 15.3; p = 0.02). Conclusion: Cardiac surgery on minimal invasive extracorporeal circulation is a platelet preservation strategy, which contributes to the beneficial effect of minimal invasive extracorporeal circulation in coagulation integrity.

scholarly journals Initial experiences with a centrifugal-pump based minimal invasive extracorporeal circulation system in pediatric congenital cardiac surgery

2019 ◽  
Vol 11 (S10) ◽  
pp. S1446-S1452
Author(s):  
Alexander Kadner ◽  
Paul Philipp Heinisch ◽  
Maris Bartkevics ◽  
Serena Wyss ◽  
Hans-Joerg Jenni ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Centrifugal Pump ◽  
Extracorporeal Circulation ◽  
Minimal Invasive ◽  
Circulation System ◽  
Congenital Cardiac Surgery

scholarly journals A method for chest drainage after pediatric cardiac surgery: A prospective randomized trial

2006 ◽  
Vol 131 (6) ◽  
pp. 1306-1309 ◽  
Author(s):  
Salvatore Agati ◽  
Carmelo Mignosa ◽  
Placido Gitto ◽  
Eugenio Santo Trimarchi ◽  
Giuseppe Ciccarello ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Randomized Trial ◽  
Pediatric Cardiac Surgery ◽  
Prospective Randomized Trial ◽  
Chest Drainage
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