Pigmented Villonodular Synovitis does not Influence the Outcome Following Cruciate-retaining Total Knee Arthroplasty: A Case- Control Study with Middle-term Follow-up Minimum 5-Year Follow-up
Abstract Background: Pigmented villonodular synovitis (PVNS) is a rare synovial disease with benign hyperplasia, which has been successfully treated with total knee arthroplasty (TKA). The purpose of this study was to investigate the middle-term follow-up results of cruciate-retaining (CR) total knee arthroplasty (TKA) in PVNS patients.Methods: 17 patients with PVNS were treated with CR TKA between 2012 and 2014. 68 patients with osteoarthritis (OA) who received CR TKA as control group. The two groups matched in a 4:1 ratio based on age,gender, body mass index (BMI) and follow-up time. In the two groups, the range of motion (ROM), Knee Society Score (KSS), revision rate, disease recurrence, complications and the survivorship curve of Kaplan-Meier implant were compared. Results: All patients were followed up at least 7 years. At the last follow-up, no patients with recurrence of PVNS were found. There was no difference in KSS between the two groups, and no patients experienced infection and death. In the PVNS group, 3 patients had stiffness complications but did not need revision. 1 patient underwent revision surgery due to periprosthetic fracture. At 7 years,the implant survivorship was 90.0% in the PVNS group and 96.6% in the control group (p = 0.54).Conclusions: This study demonstrates that the function of PVNS patients who received CR TKA has been significantly improved. The survival rate of implants in PVNS patients is similar to that of OA patients. Consequently, PVNS patients who treated with CR TKA may be an achievable option. However, patients with PVNS should pay more attention to the occurrence of postoperative stiffness complications.