scholarly journals Clear Cell Tumor of the Lung Could Be Aggressive: a case report and review of the literature

2020 ◽  
Author(s):  
leilei shen ◽  
Jixing LIN ◽  
Zhipeng REN ◽  
Bailin WANG ◽  
You Liu ◽  
...  
Keyword(s):  
Fine Needle Aspiration Biopsy ◽  
Clear Cell ◽  
Mediastinal Lymph Node ◽  
Lower Lobe ◽  
Needle Aspiration ◽  
Exact Nature ◽  
Review Of The Literature ◽  
Epithelioid Cells ◽  
Case Presentation ◽  
Clear Cell Tumor

Abstract Background: Clear cell tumors of the lung (CCTLs) are rare and mostly benign pulmonary neoplasms arising from perivascular epithelioid cells. Only approximately 100 cases have been reported, and half of them were in China. Limited details about CCTLs often cause diagnostic or therapeutic problems. Case presentation: We describe a case of a 28-year-old woman with multiple gradually replicating and enlarging nodules in the left lower lobe. The patient underwent fine-needle aspiration biopsy and was diagnosed with CCTL. A left lower lobectomy and mediastinal lymph node dissection were performed. The gradual changes in size (1.4 cm to 2.8 cm) and quantity (10 to 49) of the CCTLs in this case were the biggest differences from previously reported cases. Conclusions: CCTLs are very uncommon and mostly benign PEComatous tumors with no specific morphologic features. We present a case of CCTL with multiplicity and rapid growth, which may indicate its aggressive nature. The accumulation of similar cases will help clarify the exact nature and improve our understanding of the disease.

scholarly journals Clear cell tumor of the lung Could Be Aggressive: a case report and review of the literature

2020 ◽  
Author(s):  
leilei shen ◽  
Jixing LIN ◽  
Zhipeng REN ◽  
Bailin WANG ◽  
You Liu ◽  
...  
Keyword(s):  
Fine Needle Aspiration Biopsy ◽  
Clear Cell ◽  
Mediastinal Lymph Node ◽  
Lower Lobe ◽  
Needle Aspiration ◽  
Cell Tumor ◽  
Epithelioid Cells ◽  
Case Presentation ◽  
Clear Cell Tumor ◽  
Pulmonary Neoplasm

Abstract Background: Clear cell tumor of the lung (CCTL) is a rare and mostly benign pulmonary neoplasm arising from perivascular epithelioid cells. Only about 100 cases have been reported and half of them were in China. Limited details about CCTL often cause diagnostic or therapeutic problems. Case presentation: We describe a case of 28-year-old woman with gradually increased and enlarged multiple nodules in the left lower lobe. The patient underwent a fine-needle aspiration biopsy and was considered as CCTL. A left lower lobectomy and mediastinal lymph node dissection was performed. The gradual changes in size (1.4 cm to 2.8 cm) and quantity (10 to 49) of CCTL in this case was the biggest difference from previously reported cases. Conclusions: CCTL is a very uncommon and mostly benign PEComatous tumor with no specific morphologic features. We present a case of CCTL with multiplicity and rapid growth, which may indicate its aggressive nature. The accumulation of similar cases will help clarify its exact disease nature and to improve our understanding of such tumor.

Unusual Forms of Immature Sporulating Coccidioides immitis Diagnosed by Fine-Needle Aspiration Biopsy

2006 ◽  
Vol 130 (1) ◽  
pp. 97-100
Author(s):  
Yong Ke ◽  
Corey W. Smith ◽  
Gratian Salaru ◽  
Kim L. Joho ◽  
Malik F. Deen
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Biopsy ◽  
Lower Lobe ◽  
Grand Canyon ◽  
Needle Aspiration ◽  
Aspiration Biopsy ◽  
Coccidioides Immitis ◽  
Dimorphic Fungus ◽  
Fine Needle ◽  
Needle Aspiration Biopsy

Abstract Coccidioidomycosis is an endemic infection acquired by inhalation of the spores (arthroconidia) of the thermally dimorphic fungus, Coccidioides immitis. The arthroconidia transform into spherical cells called mature spherules in the lung. Immature spherules and other atypical forms of immature C immitis have rarely been found in vivo. We report on a case that presented unusual forms of immature sporulating C immitis in a fine-needle aspiration specimen. A 36-year-old Chinese woman, living in New Jersey for the past 10 years, presented with fever, night sweats, hemoptysis, and an abnormal chest radiograph approximately 9 months after a brief vacation trip to the Grand Canyon in Arizona. She was treated with antibiotics for 4 weeks without improvement. Subsequent chest computed tomography showed a 3-cm cavitary lesion in the right lower lobe of the lung. Fine-needle aspiration biopsy revealed diverse morphologic forms of a fungus that was confirmed by culture as immature sporulating C immitis.

scholarly journals Cardiac Epithelioid PEComa: Report of Two Cases and Review of the Literature

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Huilin Niu ◽  
F. W. Wang ◽  
Paul J. Zhang ◽  
Zhanyong Bing
Keyword(s):  
Clear Cell ◽  
Coagulation Necrosis ◽  
Review Of The Literature ◽  
Epithelioid Cells ◽  
Adult Case ◽  
Pediatric Case ◽  
High Mitotic Activity ◽  
Atypical Mitosis ◽  
Malignant Behavior ◽  
Hmb 45

Cardiac PEComa is very rare. We reported two cases of epithelioid PEComas, one in an adult and one in a 2-year-old child. Both tumors were composed of sheets of epithelioid cells with coagulation necrosis. In addition, the adult case showed marked nuclear atypia and high mitotic activity with atypical mitosis and the pediatric case showed unusual clear cell features. Immunohistochemically, both tumors were positive for HMB-45 and SMA and negative for S100 and cytokeratin. Electron microscopy was performed in the pediatric case and showed premelanosomes. The adult patient developed extensive metastasis indicating malignant behavior. Prior to the two cases, only 5 other cases of cardiac PEComa were reported and the literatures are reviewed.

Clear cell hidradenoma of the second digit: A review of the literature with case presentation

1997 ◽  
Vol 36 (1) ◽  
pp. 21-23 ◽  
Author(s):  
Alan H. Feldman ◽  
Willard J. Niemi ◽  
Peter A. Blume ◽  
Dennis M. Chaney
Keyword(s):  
Clear Cell ◽  
Review Of The Literature ◽  
Case Presentation

scholarly journals Clear cell tumor of the lung could be aggressive: a case report and review of the literature

2020 ◽  
Vol 15 (1) ◽  
Author(s):  
Leilei Shen ◽  
Jixing Lin ◽  
Zhipeng Ren ◽  
Bailin Wang ◽  
You Liu ◽  
...  
Keyword(s):  
Case Report ◽  
Clear Cell ◽  
Cell Tumor ◽  
Review Of The Literature ◽  
Clear Cell Tumor

scholarly journals The first case of gland inclusion in an intrapulmonary lymph node: a mimic of metastasis

2019 ◽  
Vol 17 (1) ◽  
Author(s):  
Chenglong Wang ◽  
Yijia Cao ◽  
Min Zeng ◽  
Lijuan Wang ◽  
Xiaojing Cao ◽  
...  
Keyword(s):  
Lymph Node ◽  
Mediastinal Lymph Node ◽  
Needle Aspiration ◽  
The Body ◽  
Case Presentation ◽  
Ectopic Tissue ◽  
First Case ◽  
Primary Lung Adenocarcinoma ◽  
The Right

Abstract Background Lymph node inclusions are foci of ectopic tissue in lymph nodes, which were reported in different areas of the body. However, inclusions in the mediastinal lymph node are rare. Here, we report the first case of glandular inclusion within the parenchyma of the intrapulmonary lymph node in a patient with primary lung adenocarcinoma. Case presentation A computed tomography (CT) scan showed a solid pulmonary nodule in the right upper lobe in a 44-year-old man. After a fine needle aspiration biopsy diagnosis of adenocarcinoma, lobectomy and lymph dissection were performed. Histological sections of the lung demonstrated a papillary predominant adenocarcinoma and one intrapulmonary lymph node, which displayed glandular inclusion occupying the node parenchyma. The gland inclusion was very similar to metastasis, but was formed by two layers of epithelial cells, and the abluminal cells were positive for P63, P40, and CK5/6. The patient has remained alive without recurrence and metastasis at the last follow-up before publication. Conclusions It is very important to correctly diagnose a lymph node inclusion for proper clinical management.

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