scholarly journals Clear cell tumor of the lung Could Be Aggressive: a case report and review of the literature

2020 ◽  
Author(s):  
leilei shen ◽  
Jixing LIN ◽  
Zhipeng REN ◽  
Bailin WANG ◽  
You Liu ◽  
...  
Keyword(s):  
Fine Needle Aspiration Biopsy ◽  
Clear Cell ◽  
Mediastinal Lymph Node ◽  
Lower Lobe ◽  
Needle Aspiration ◽  
Cell Tumor ◽  
Epithelioid Cells ◽  
Case Presentation ◽  
Clear Cell Tumor ◽  
Pulmonary Neoplasm

Abstract Background: Clear cell tumor of the lung (CCTL) is a rare and mostly benign pulmonary neoplasm arising from perivascular epithelioid cells. Only about 100 cases have been reported and half of them were in China. Limited details about CCTL often cause diagnostic or therapeutic problems. Case presentation: We describe a case of 28-year-old woman with gradually increased and enlarged multiple nodules in the left lower lobe. The patient underwent a fine-needle aspiration biopsy and was considered as CCTL. A left lower lobectomy and mediastinal lymph node dissection was performed. The gradual changes in size (1.4 cm to 2.8 cm) and quantity (10 to 49) of CCTL in this case was the biggest difference from previously reported cases. Conclusions: CCTL is a very uncommon and mostly benign PEComatous tumor with no specific morphologic features. We present a case of CCTL with multiplicity and rapid growth, which may indicate its aggressive nature. The accumulation of similar cases will help clarify its exact disease nature and to improve our understanding of such tumor.

scholarly journals Clear Cell Tumor of the Lung Could Be Aggressive: a case report and review of the literature

2020 ◽  
Author(s):  
leilei shen ◽  
Jixing LIN ◽  
Zhipeng REN ◽  
Bailin WANG ◽  
You Liu ◽  
...  
Keyword(s):  
Fine Needle Aspiration Biopsy ◽  
Clear Cell ◽  
Mediastinal Lymph Node ◽  
Lower Lobe ◽  
Needle Aspiration ◽  
Exact Nature ◽  
Review Of The Literature ◽  
Epithelioid Cells ◽  
Case Presentation ◽  
Clear Cell Tumor

Abstract Background: Clear cell tumors of the lung (CCTLs) are rare and mostly benign pulmonary neoplasms arising from perivascular epithelioid cells. Only approximately 100 cases have been reported, and half of them were in China. Limited details about CCTLs often cause diagnostic or therapeutic problems. Case presentation: We describe a case of a 28-year-old woman with multiple gradually replicating and enlarging nodules in the left lower lobe. The patient underwent fine-needle aspiration biopsy and was diagnosed with CCTL. A left lower lobectomy and mediastinal lymph node dissection were performed. The gradual changes in size (1.4 cm to 2.8 cm) and quantity (10 to 49) of the CCTLs in this case were the biggest differences from previously reported cases. Conclusions: CCTLs are very uncommon and mostly benign PEComatous tumors with no specific morphologic features. We present a case of CCTL with multiplicity and rapid growth, which may indicate its aggressive nature. The accumulation of similar cases will help clarify the exact nature and improve our understanding of the disease.

scholarly journals Intrathyroidal Clear Cell Tumor of Parathyroid Origin with Review of Literature

2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Daniela Pirela ◽  
Daniela Treitl ◽  
Siba El Hussein ◽  
Robert Poppiti ◽  
Thomas Mesko ◽  
...  
Keyword(s):  
Clear Cell ◽  
Treatment Plan ◽  
Management Strategies ◽  
Needle Aspiration ◽  
Cell Tumor ◽  
Thyroid Function Tests ◽  
Cell Adenoma ◽  
Clear Cell Tumor ◽  
Thyroid Lobectomy ◽  
Diffuse Positivity

Water-clear cell adenoma (WCCA) of the parathyroid gland is an exceedingly rare neoplasm. To date, 17 cases have been reported in the literature, with only one of them being intrathyroidal. Here we report a case of a 34-year-old woman who presented for evaluation of a goiter and was found to have a thyroid nodule and abnormal thyroid function tests (TFT). Fine needle aspiration biopsy of the nodule revealed thyroid follicular cells without atypia and subsequent Afirma® Gene Expression Classifier (GEC) testing results were suspicious for malignancy. As a result, the patient underwent a right thyroid lobectomy and isthmusectomy. Histological sections revealed an intrathyroidal nodule consistent with a clear cell neoplasm of parathyroid origin. The histologic appearance together with the immune profile was diagnostic of WCCA, with diffuse positivity for GATA3, focal weak positivity for parathyroid hormone, and negativity for PAX8, thyroglobulin, TTF1, synaptophysin, chromogranin, and S100p. Our study focuses on the clinical presentation, current management strategies, and review of the available literature surrounding this rare diagnosis. The ultimate goal is to help endocrinologists and surgeons establish a foundational treatment plan for intrathyroidal clear cell tumor cases.

scholarly journals A rare cause of hemoptysis: benign sugar (clear) cell tumor of the lung

2004 ◽  
Vol 25 (4) ◽  
pp. 652-654 ◽  
Author(s):  
A SANTANA ◽  
F NUNES ◽  
N HO ◽  
T TAKAGAKI
Keyword(s):  
Clear Cell ◽  
Cell Tumor ◽  
Clear Cell Tumor

A Clear Cell Tumor of the Lung Presenting as a Rapidly Growing Coin Lesion: Is It Really a Benign Tumor?

2011 ◽  
Vol 91 (2) ◽  
pp. 588-591 ◽  
Author(s):  
Alexandros Kalkanis ◽  
Myrto Trianti ◽  
Kostas Psathakis ◽  
Charalampos Mermigkis ◽  
Dimitrios Kalkanis ◽  
...  
Keyword(s):  
Benign Tumor ◽  
Clear Cell ◽  
Cell Tumor ◽  
Clear Cell Tumor ◽  
Coin Lesion

Clear Cell Tumor of the Colon in an 8.5-Year-Old Girl

2001 ◽  
Vol 33 (2) ◽  
pp. 196-199
Author(s):  
Vicky Zolota ◽  
Anna Batistatou ◽  
Maria Melachrinou ◽  
Evangelos Tzorakoeleftherakis ◽  
Vassilios Pastromas ◽  
...  
Keyword(s):  
Clear Cell ◽  
Cell Tumor ◽  
Clear Cell Tumor

Unusual clear cell tumor of the kidney in infancy

1981 ◽  
Vol 5 (6) ◽  
pp. 581-586 ◽  
Author(s):  
Alan D. Glick ◽  
Kyi Toe Tham ◽  
Nai Kwong Leung ◽  
Song Win Wong
Keyword(s):  
Clear Cell ◽  
Cell Tumor ◽  
Clear Cell Tumor

Unusual Forms of Immature Sporulating Coccidioides immitis Diagnosed by Fine-Needle Aspiration Biopsy

2006 ◽  
Vol 130 (1) ◽  
pp. 97-100
Author(s):  
Yong Ke ◽  
Corey W. Smith ◽  
Gratian Salaru ◽  
Kim L. Joho ◽  
Malik F. Deen
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Biopsy ◽  
Lower Lobe ◽  
Grand Canyon ◽  
Needle Aspiration ◽  
Aspiration Biopsy ◽  
Coccidioides Immitis ◽  
Dimorphic Fungus ◽  
Fine Needle ◽  
Needle Aspiration Biopsy

Abstract Coccidioidomycosis is an endemic infection acquired by inhalation of the spores (arthroconidia) of the thermally dimorphic fungus, Coccidioides immitis. The arthroconidia transform into spherical cells called mature spherules in the lung. Immature spherules and other atypical forms of immature C immitis have rarely been found in vivo. We report on a case that presented unusual forms of immature sporulating C immitis in a fine-needle aspiration specimen. A 36-year-old Chinese woman, living in New Jersey for the past 10 years, presented with fever, night sweats, hemoptysis, and an abnormal chest radiograph approximately 9 months after a brief vacation trip to the Grand Canyon in Arizona. She was treated with antibiotics for 4 weeks without improvement. Subsequent chest computed tomography showed a 3-cm cavitary lesion in the right lower lobe of the lung. Fine-needle aspiration biopsy revealed diverse morphologic forms of a fungus that was confirmed by culture as immature sporulating C immitis.

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