scholarly journals The Impact of Using Mobile Applications on Health Outcomes in Patient Self-Management of Oral Anticoagulation Therapy

2021 ◽  
Author(s):  
Hamid Moghaddasi ◽  
Mohammadreza Naderi Haji ◽  
Babak Sharif-Kashani ◽  
Alireza Kazemi
Keyword(s):  
Health Outcomes ◽  
Therapeutic Range ◽  
Oral Anticoagulation ◽  
Mobile Applications ◽  
Mobile Application ◽  
Anticoagulation Therapy ◽  
Self Management ◽  
Oral Anticoagulation Therapy ◽  
The Mean ◽  
The Impact

Abstract Background Between one and two percent of the population of the developed countries are currently treated with oral anticoagulation therapy. The transition of all or part of the responsibility for therapy management to the patient is an appropriate strategy to respond increasing demand for oral anticoagulation therapy. The main objective of this original study was to investigate the impact of using mobile applications on health outcomes in patient self-management of oral anticoagulation therapy. Methods The papers reviewed in this study had two key characteristics: firstly, they were written in English, and secondly, they used mobile application in oral anticoagulation therapy. An Android mobile application called XrinA was developed to provide warfarin patient self-management. The study was conducted following a Before-After study design. In the Before and After periods, patients were treated as usual and by using the developed application, respectively. Results In the Before period, the mean percentage of International Normalized Ratios (INRs) within the therapeutic range and Time in Therapeutic Range (TTR) of patients was 31.63% and 34.4%, respectively. In the After period, the mean percentage of INRs within the therapeutic range and TTR of patients was 41.41% and 49.97%, respectively. In the After period, the mean INRs within the therapeutic range and the mean TTR increased by 9.78% and 15.57%, respectively. Conclusions Overall, the use of mHealth applications improved outcomes in patient self-management of oral anticoagulation therapy in terms of the percentage of INRs within the therapeutic range and TTR.

scholarly journals Does self-management of oral anticoagulation therapy improve quality of life and anxiety?

2010 ◽  
Vol 28 (2) ◽  
pp. 134-140 ◽  
Author(s):  
D. McCahon ◽  
E. T. Murray ◽  
K. Murray ◽  
R. L. Holder ◽  
D. A. Fitzmaurice
Keyword(s):  
Quality Of Life ◽  
Oral Anticoagulation ◽  
Anticoagulation Therapy ◽  
Self Management ◽  
Improve Quality ◽  
Oral Anticoagulation Therapy

scholarly journals IMPACT OF PHARMACIST LED ANTICOAGULATION MONITORING AND PATIENT EDUCATION ON ORAL ANTICOAGULATION THERAPY WITH ACENOCOUMAROL

2017 ◽  
Vol 10 (10) ◽  
pp. 314
Author(s):  
Poojitha Reddy Reddy ◽  
Omsri Mounika ◽  
Gaddam Chandrika ◽  
Aldrich Franklin ◽  
Ramesh M ◽  
...  
Keyword(s):  
Patient Education ◽  
Drug Interactions ◽  
Oral Anticoagulation ◽  
Anticoagulation Therapy ◽  
Therapeutic Index ◽  
International Normalized Ratio ◽  
Rank Test ◽  
Oral Anticoagulation Therapy ◽  
Before And After ◽  
The Impact

  Objective: Acenocoumarol is anoral anticoagulant with narrow therapeutic index, and the ideal dose of anticoagulation lies between International normalized ratio (INR) values of 2.0 and 3.5. Lack of monitoring and knowledge on acenocoumarol therapy may compromise patient’s safety resulting in under- or over-anticoagulation. A study was conducted to monitor for the safety of anticoagulation therapy, achievement of goal INR levels and to assess the impact of pharmacist led anticoagulation monitoring and patient education on the rational use of acenocoumarol in patients admitted in cardiology wards with thromboembolic disorders.Methods: The study was conducted in 70 patients; data collection was done, prescriptions were analyzed for drug-drug interactions and adverse drug reactions (ADRs). Patients’ knowledge on acenocoumarol therapy was assessed using a self-developed questionnaire at the baseline, then were subjected to a detailed patient education and on an average each patient received three sessions of education. They were again made to answer the same questionnaire on the day of discharge. The mean score of the responses before and after education was compared statistically using Wilcoxon signed rank test and McNemar test.Results: There were 60% patients under anticoagulated with the INR range of >2.0. 123 drug interactions were observed in 58 patients, on an average of 2 interactions per prescription, but no ADRs were observed. 59 patients (84.3%) showed significant overall improvement in knowledge on anticoagulation therapy following education.Conclusion: This study implies the role of clinical pharmacists in achieving better clinical outcomes in patients receiving oral anticoagulation therapy with acenocoumarol.

scholarly journals Poor Agreement among Prothrombin Time International Normalized Ratio Methods: Comparison of Seven Commercial Reagents

2005 ◽  
Vol 51 (3) ◽  
pp. 553-560 ◽  
Author(s):  
Juha Horsti ◽  
Helena Uppa ◽  
Juhani A Vilpo
Keyword(s):  
Clinical Practice ◽  
Patient Care ◽  
Prothrombin Time ◽  
Oral Anticoagulation ◽  
Anticoagulation Therapy ◽  
International Normalized Ratio ◽  
Poor Agreement ◽  
Oral Anticoagulation Therapy ◽  
The Mean ◽  
The Difference

Abstract Background: Prothrombin time (PT) has long been the most popular test for monitoring oral anticoagulation therapy. The International Normalized Ratio (INR) was introduced to overcome the problem of marked variation in PT results among laboratories and the various recommendations for patient care. According to this principle, all reagents should be calibrated to give identical results and the same patient care globally. This is necessary for monitoring of single patients and for application of the results of anticoagulation trials and guidelines to clinical practice. Methods: We took blood samples from 150 patients for whom oral anticoagulation had been prescribed. Plasmas were separated and PTs determined by use of seven commercial reagents and four calibrator sets. The differences in results were assessed by plotting, for each possible pair of methods, the differences in INR values for each sample against the mean INR value (Bland-Altman difference plots). Results: Mean results differed significantly (P <0.001) for 17 of 21 possible paired comparisons of methods. Only two pairs of methods produced very similar results when assessed for problems of substantial differences in INR values; a significant, systematic increase in the difference with INR; and a significant systematic increase in the variation in difference with increasing INR values. Conclusions: The agreement among several (and perhaps most) commercial INR methods is poor. The failure of current calibration strategies may severely compromise both the monitoring of individual patients and the application of oral anticoagulation guidelines and trial results to clinical practice.

Oral Anticoagulation Therapy in Children: Successfully Controlled by Self-Management

2004 ◽  
Vol 7 (4) ◽  
pp. E321-E325 ◽  
Author(s):  
Thomas Decker Christensen ◽  
Niels Trolle Andersen ◽  
Ole Kromann Hansen ◽  
Vibeke Elisabeth Hjortdal ◽  
J. Michael Hasenkam
Keyword(s):  
Oral Anticoagulation ◽  
Anticoagulation Therapy ◽  
Self Management ◽  
Oral Anticoagulation Therapy
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