Utility of oxygen insufflation through working channel during fiberoptic intubation in apneic patients: a prospective randomized controlled study

Abstract Background: Airway management is a part of routine anesthetic procedures; however, serious complications, including hypoxia and death, are known to occur in cases of difficult airways. Therefore, alternative techniques such as fiberoptic bronchoscope-assisted intubation (FOB intubation) should be considered, although this method requires more time and offers a limited visual field than does intubation with a direct laryngoscope. Oxygen insufflation through the working channel during FOB intubation could minimize the risk of desaturation and improve the visual field. Therefore, the aim of this prospective randomized controlled study was to evaluate the utility and safety of oxygen insufflation through the working channel during FOB intubation in apneic patients. Methods: Thirty-six patients were randomly allocated to an N group (no oxygen insufflation) or an O group (oxygen insufflation). After preoxygenation, FOB intubation was performed with (O group) or without (N group) oxygen insufflation in apneic patients. The primary outcome was the velocity of decrease in the partial pressure of oxygen (PaO2) during FOB intubation (VPaO2, mmHg/sec) defined as the difference of PaO2 before and after intubation divided by the time to intubation. The secondary outcomes included the success rate for FOB intubation, time to intubation, visual field during FOB intubation, findings of arterial blood gas analysis, and occurrence of FOB intubation-related complications. Results: We found that VPaO2 was significantly greater in the N group than in the O group (1.0 ± 0.4 vs. 0.4 ± 0.4; p < 0.001), while the visual field was similar between groups. There were no significant intergroup differences in the secondary outcomes. Conclusions: These findings suggest that oxygen insufflation through the working channel during FOB intubation aids in extending the apneic window during the procedure.Trial registration: ClinicalTrials.gov, NCT02625194, registered at December 9, 2015

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Utility of oxygen insufflation through working channel during fiberoptic intubation in apneic patients: a prospective randomized controlled study

10.21203/rs.3.rs-50531/v3 ◽

2020 ◽

Author(s):

Go Un Roh ◽

Joon Gwon Kang ◽

Jung Youn Han ◽

Chul Ho Chang

Keyword(s):

Visual Field ◽

Gas Analysis ◽

Randomized Controlled Study ◽

Controlled Study ◽

Fiberoptic Intubation ◽

Arterial Blood Gas ◽

Randomized Controlled ◽

Arterial Blood ◽

Group Oxygen ◽

Secondary Outcomes

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Utility of Oxygen Insufflation Through Working Channel During Fiberoptic Intubation: a Prospective Randomized Controlled Study

10.21203/rs.3.rs-50531/v1 ◽

2020 ◽

Author(s):

Go Un Roh ◽

Joon Gwon Kang ◽

Jung Youn Han ◽

Chul Ho Chang

Keyword(s):

Visual Field ◽

Gas Analysis ◽

Randomized Controlled Study ◽

Controlled Study ◽

Fiberoptic Intubation ◽

Arterial Blood Gas ◽

Randomized Controlled ◽

Arterial Blood ◽

Group Oxygen ◽

Secondary Outcomes

Abstract Background: Airway management is a part of routine anesthetic procedures; however, serious complications, including hypoxia and death, are known to occur in cases of difficult airways. Therefore, alternative techniques such as fiberoptic bronchoscope-assisted intubation (FOBI) should be considered, although this method requires more time and offers a limited visual field than does intubation with a direct laryngoscope. Oxygen insufflation through the working channel during FOBI could minimize the risk of desaturation and improve the visual field. Therefore, the aim of this prospective randomized controlled study was to evaluate the utility and safety of oxygen insufflation through the working channel during FOBI. Methods: Thirty-six patients were randomly allocated to an N group (no oxygen insufflation) or an O group (oxygen insufflation). After preoxygenation, FOBI was performed with (O group) or without (N group) oxygen insufflation. The primary outcome was the velocity of decrease in the partial pressure of oxygen during FOBI (VPaO2), while secondary outcomes included the success rate for FOBI, time to intubation, visual field during FOBI, findings of arterial blood gas analysis, and occurrence of FOBI-related complications. Results: We found that VPaO2 was significantly greater in the N group than in the O group (1.01 ± 0.39 vs. 0.42 ± 0.42; p < 0.001), while the visual field was similar between groups. There were no significant intergroup differences in the secondary outcomes. Conclusions: These findings suggest that oxygen insufflation through the working channel during FOBI aids in extending the apneic window during the procedure.Trial registration: ClinicalTrials.gov, NCT02625194, registered at December 9, 2015

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Utility of oxygen insufflation through working channel during fiberoptic intubation in apneic patients: a prospective randomized controlled study

10.21203/rs.3.rs-50531/v2 ◽

2020 ◽

Author(s):

Go Un Roh ◽

Joon Gwon Kang ◽

Jung Youn Han ◽

Chul Ho Chang

Keyword(s):

Visual Field ◽

Gas Analysis ◽

Randomized Controlled Study ◽

Controlled Study ◽

Fiberoptic Intubation ◽

Arterial Blood Gas ◽

Randomized Controlled ◽

Arterial Blood ◽

Group Oxygen ◽

Secondary Outcomes

Abstract Background: Airway management is a part of routine anesthetic procedures; however, serious complications, including hypoxia and death, are known to occur in cases of difficult airways. Therefore, alternative techniques such as fiberoptic bronchoscope-assisted intubation (FOBI) should be considered, although this method requires more time and offers a limited visual field than does intubation with a direct laryngoscope. Oxygen insufflation through the working channel during FOBI could minimize the risk of desaturation and improve the visual field. Therefore, the aim of this prospective randomized controlled study was to evaluate the utility and safety of oxygen insufflation through the working channel during FOBI in apneic patients. Methods: Thirty-six patients were randomly allocated to an N group (no oxygen insufflation) or an O group (oxygen insufflation). After preoxygenation, FOBI was performed with (O group) or without (N group) oxygen insufflation in apneic patients. The primary outcome was the velocity of decrease in the partial pressure of oxygen (PaO2) during FOBI (VPaO2, mmHg/sec) defined as the difference of PaO2 before and after intubation divided by the time to intubation. The secondary outcomes included the success rate for FOBI, time to intubation, visual field during FOBI, findings of arterial blood gas analysis, and occurrence of FOBI-related complications. Results: We found that VPaO2 was significantly greater in the N group than in the O group (1.01 ± 0.39 vs. 0.42 ± 0.42; p < 0.001), while the visual field was similar between groups. There were no significant intergroup differences in the secondary outcomes. Conclusions: These findings suggest that oxygen insufflation through the working channel during FOBI aids in extending the apneic window during the procedure.Trial registration: ClinicalTrials.gov, NCT02625194, registered at December 9, 2015

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Utility of oxygen insufflation through working channel during fiberoptic intubation in apneic patients: a prospective randomized controlled study

BMC Anesthesiology ◽

10.1186/s12871-020-01201-9 ◽

2020 ◽

Vol 20 (1) ◽

Author(s):

Go Un Roh ◽

Joon Gwon Kang ◽

Jung Youn Han ◽

Chul Ho Chang

Keyword(s):

Visual Field ◽

Gas Analysis ◽

Randomized Controlled Study ◽

Controlled Study ◽

Fiberoptic Intubation ◽

Randomized Controlled ◽

Link Type ◽

Arterial Blood ◽

Group Oxygen ◽

Secondary Outcomes

Abstract Background Airway management is a part of routine anesthetic procedures; however, serious complications, including hypoxia and death, are known to occur in cases of difficult airways. Therefore, alternative techniques such as fiberoptic bronchoscope-assisted intubation (FOB intubation) should be considered, although this method requires more time and offers a limited visual field than does intubation with a direct laryngoscope. Oxygen insufflation through the working channel during FOB intubation could minimize the risk of desaturation and improve the visual field. Therefore, the aim of this prospective randomized controlled study was to evaluate the utility and safety of oxygen insufflation through the working channel during FOB intubation in apneic patients. Methods Thirty-six patients were randomly allocated to an N group (no oxygen insufflation) or an O group (oxygen insufflation). After preoxygenation, FOB intubation was performed with (O group) or without (N group) oxygen insufflation in apneic patients. The primary outcome was the velocity of decrease in the partial pressure of oxygen (PaO2) during FOB intubation (VPaO2, mmHg/sec) defined as the difference of PaO2 before and after intubation divided by the time to intubation. The secondary outcomes included the success rate for FOB intubation, time to intubation, visual field during FOB intubation, findings of arterial blood gas analysis, and occurrence of FOB intubation-related complications. Results We found that VPaO2 was significantly greater in the N group than in the O group (1.0 ± 0.4 vs. 0.4 ± 0.4; p < 0.001), while the visual field was similar between groups. There were no significant intergroup differences in the secondary outcomes. Conclusions These findings suggest that oxygen insufflation through the working channel during FOB intubation aids in extending the apneic window during the procedure. Trial registration ClinicalTrials.gov, NCT02625194, registered at December 9, 2015.

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The comparison of heparinized insulin syringes and safety-engineered blood gas syringes used in arterial blood gas sampling in the ED setting (randomized controlled study)

The American Journal of Emergency Medicine ◽

10.1016/j.ajem.2014.01.020 ◽

2014 ◽

Vol 32 (5) ◽

pp. 432-437 ◽

Cited By ~ 4

Author(s):

Sevcan Baki Baskın ◽

Neşe Çolak Oray ◽

Sedat Yanturalı ◽

Başak Bayram

Keyword(s):

Randomized Controlled Study ◽

Controlled Study ◽

Blood Gas ◽

Arterial Blood Gas ◽

Gas Sampling ◽

Randomized Controlled ◽

Arterial Blood

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Prospective Randomized Controlled Study to assess the Role of Dexmedetomidine on Perioperative Hemodynamics in Patients with Supratentorial Tumor undergoing Surgery

Research & Innovation in Anesthesia ◽

10.5005/jp-journals-10049-0024 ◽

2017 ◽

Vol 2 (1) ◽

pp. 14-17

Author(s):

Sachin Vaishnav ◽

Anita Shetty ◽

Manjula Sarkar

Keyword(s):

Blood Pressure ◽

Placebo Group ◽

Arterial Blood Pressure ◽

Randomized Controlled Study ◽

Controlled Study ◽

Randomized Controlled ◽

Arterial Blood ◽

Supratentorial Tumor ◽

Duration Of Surgery

ABSTRACT The stress response to an intense painful surgical stimulus is characterized by activation of the sympathetic nervous system and an increased secretion of the stress hormones. The ability of the alpha agonist dexmedetomidine (DEX) to decrease heart rate (HR) and arterial blood pressure in perioperative period was tested. One hundred and thirty two patients undergoing craniotomy for supratentorial tumor were randomly distributed to receive either saline (B group) or DEX (A group). The placebo group received saline, whereas the treatment group (A group) received a single bolus dose of DEX (1μg/kg) intravenously over 10 minutes before induction of anesthesia. Hemodynamic parameters, such as HR and arterial blood pressure were measured. Both the groups were comparable with respect to age, sex, American Society for Anesthesiologist grade, and duration of surgery. The arterial blood pressure and HR were found to be lower in the DEX group when compared with the placebo group. How to cite this article Vaishnav S, Shetty A, Sarkar M. Prospective Randomized Controlled Study to assess the Role of Dexmedetomidine on Perioperative Hemodynamics in Patients with Supratentorial Tumor undergoing Surgery. Res Inno in Anesth 2017;2(1):14-17.

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A randomized controlled study comparing dexmedetomidine-midazolam with fentanyl-midazolam for sedation during awake fiberoptic intubation in anticipated difficult airway

Anesthesia Essays and Researches ◽

10.4103/aer.aer_44_20 ◽

2020 ◽

Vol 14 (2) ◽

pp. 271

Author(s):

JayBrijesh Singh Yadav ◽

Urvashi Yadav ◽

Dhiraj Srivastava ◽

Swati Srivastava

Keyword(s):

Difficult Airway ◽

Randomized Controlled Study ◽

Controlled Study ◽

Fiberoptic Intubation ◽

Randomized Controlled ◽

Awake Fiberoptic Intubation

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An analysis of the treatment effect of two modes of oxygenation on patients with radiation pneumonia complicated by respiratory failure

Technology and Health Care ◽

10.3233/thc-213597 ◽

2022 ◽

pp. 1-12

Author(s):

Dong Xing ◽

Li Chen ◽

Lantao Wang ◽

Jing Jin ◽

Dong Liu ◽

...

Keyword(s):

Respiratory Failure ◽

Tidal Volume ◽

Blood Gas Analysis ◽

Assisted Ventilation ◽

Gas Analysis ◽

Controlled Study ◽

Apache Ii Score ◽

Arterial Blood Gas ◽

Arterial Blood ◽

Radiation Pneumonia

BACKGROUND: Stereotactic radiotherapy (SBRT) is widely used in the treatment of thoracic cancer. OBJECTIVE: To evaluate the efficacy of a non-rebreather mask (NRBM) and high-flow nasal cannula (HFNC) in patients with radiation pneumonia complicated with respiratory failure. METHODS: This was a single-center randomized controlled study. Patients admitted to the EICU of the Fourth Hospital of Hebei Medical University were selected and divided into NRBM and HFNC group. Arterial blood gas analysis, tidal volume, respiratory rates and the cases of patients receiving invasive assisted ventilation were collected at 0, 4, 8, 12, 24, 48, and 72 h after admission. RESULTS: (1) The PaO2/FiO2, respiratory rates, and tidal volume between the two groups at 0, 4, 8, 12, 24, 48, and 72 h were different, with F values of 258.177, 294.121, and 134.372, all P< 0.01. These indicators were different under two modes of oxygenation, with F values of 40.671, 168.742, and 55.353, all P< 0.01, also varied with time, with an F value of 7.480, 9.115, and 12.165, all P< 0.01. (2) The incidence of trachea intubation within 72 h between HFNC and NRBM groups (23 [37.1%] vs. 34 [54.0%], P< 0.05). The transition time to mechanical ventilation in the HFNC and NRBM groups (55.3 ± 3.2 h vs. 45.9 ± 3.6 h, P< 0.05). (3) The risk of intubation in patients with an APACHE-II score > 23 was 2.557 times than score ⩽ 23, and the risk of intubation in the NRBM group was 1.948 times more than the HFNC group (P< 0.05). CONCLUSION: Compared with the NRBM, HFNC can improve the oxygenation state of patients with radiation pneumonia complicated with respiratory failure in a short time, and reduce the incidence of trachea intubation within 72 h.

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