scholarly journals The Appropriate Acquisition Time Interval Following Injection of 99mTc-Sestamibi with Water Protocol in Single Photon Emission Computed Tomography Myocardial Perfusion Imaging: First Experience in Indonesia

2021 ◽  
Author(s):  
Nora Anggun Prasetyo ◽  
Erwin Affandi Soeriadi ◽  
Hendra Budiawan ◽  
Achmad Hussein Sundawa Kartamihardja
Keyword(s):  
Myocardial Perfusion Imaging ◽  
Myocardial Perfusion ◽  
Perfusion Imaging ◽  
Stress Test ◽  
Photon Emission ◽  
Acquisition Time ◽  
Emission Computed Tomography ◽  
Time Interval ◽  
Background Ratio ◽  
Significant Difference

Abstract BackgroundAccording to EANM/ESC guideline, image acquisitions in stress test should be begun at 30-60 minutes after tracer administration. Our center is a referral hospital for nuclear medicine imaging with many patients but limited number of gamma camera. The shorter time between injection of radiopharmaceutical and imaging acquisition will lead to more examination can be done.The aim of this study was to evaluate the appropriate acquisition time interval with water protocol in 99mTc-Sestamibi SPECT myocardial perfusion imaging.MethodsPatients who were referred to undergo stress MPI between October 2020 to December 2020 were included in this study. Cardiac stress procedure was performed using treadmill with modified Bruce Protocol. Subjects should drink a total of 330 mL water following 99mTc-Sestamibi injection. Image acquisitions were performed 10 and 30 minutes afterwards. Quantitative assessment was done by calculated target background ratio (TBR). Statistical analysis was performed using student t-test with Microsoft Excel version 2019. P-value < 0.05 was considered to be statistically significance.ResultsThirty out of 35 subjects were included in this study. Sixteen of them are male and 14 are female with mean of age was 48.7 years old (28 – 80). Mean target background uptake ratio (TBR) in 10- and 30-minutes images were 0.67 (0.44 – 1.11) and 0.76 (0.43 – 1.18) respectively (p-value = 0.15).ConclusionThere was no significant difference of target to background ratio between acquisition time 10- and 30-minutes following injection of 99mTc-Sestamibi with water protocol in myocardial perfusion imaging.Trial registrationNot applicable.

Myocardial perfusion imaging using technetium-99m sestamibi in asymptomatic diabetic patients

2011 ◽  
Vol 50 (01) ◽  
pp. 3-8 ◽  
Author(s):  
A. Mohagheghie ◽  
M. N. Ahmadabadi ◽  
D. K. Hedayat ◽  
M. R. Pourbehi ◽  
M. Assadi
Keyword(s):  
Myocardial Perfusion Imaging ◽  
Myocardial Perfusion ◽  
Perfusion Imaging ◽  
Odds Ratio ◽  
Photon Emission ◽  
Silent Myocardial Ischemia ◽  
Emission Computed Tomography ◽  
Diabetic Patients ◽  
Technetium 99M Sestamibi ◽  
Technetium 99M

SummaryMyocardial perfusion single-photon emission computed tomography (SPECT) has been extensively applied in the clinical assessment of patients with diabetes mellitus. The aim of the present study was to evaluate stress technetium- 99m sestamibi SPECT MPI perfusion in silent myocardial ischemia and its association with some clinical and laboratory parameters in an asymptomatic diabetic population. Patients, material, methods: 83 subjects (age: 57.1 ± 6.9 years) with at least five years history of type 2 diabetes, and no suspected or documented coronary artery disease (CAD) accomplished myocardial perfusion imaging; angiography was also performed in patients with abnormal MPI. Results: MPI results showed that 58 patients had normal myocardial perfusion, while 25 patients showed perfusion defects (23 reversible and 2 fixed) on MPI. 12 out of the 25 (48%) with abnormal MPI findings represented abnormal angiography. We observed that pretest likelihood of CAD (odds ratio 2.32; 95%-CI: 1.05–5.13; p = 0.038) and higher HbA1c level (odds ratio 1.70; 95%-CI, 1.07–2.71; p = 0.02) were independently associated with abnormal MPI. Conclusion: Occult CAD was present on MPI in 1/3 patients with DM without abnormal electro cardiographic findings or evidence of peripheral arterial disease.

scholarly journals Detecting Myocardial Ischemia With 99mTechnetium-Tetrofosmin Myocardial Perfusion Imaging in Ischemic Stroke

2017 ◽  
Vol 7 (4) ◽  
pp. 164-168 ◽  
Author(s):  
Sotirios Giannopoulos ◽  
Sofia Markoula ◽  
Chrissa Sioka ◽  
Sofia Zouroudi ◽  
Maria Spiliotopoulou ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Myocardial Perfusion Imaging ◽  
Myocardial Perfusion ◽  
Myocardial Ischemia ◽  
Perfusion Imaging ◽  
Single Photon ◽  
Photon Emission ◽  
Emission Computed Tomography ◽  
Spect Mpi ◽  
Artery Disease

Background: To assess the myocardial status in patients with stroke, employing myocardial perfusion imaging (MPI) with 99mTechnetium-tetrofosmin (99mTc-TF)-single-photon emission computed tomography (SPECT). Methods: Fifty-two patients with ischemic stroke were subjected to 99mTc-TF-SPECT MPI within 1 month after stroke occurrence. None of the patients had any history or symptoms of coronary artery disease or other heart disease. Myocardial perfusion imaging was evaluated visually using a 17-segment polar map. Myocardial ischemia (MIS) was defined as present when the summed stress score (SSS) was >4; MIS was defined as mild when SSS was 4 to 8, and moderate/severe with SSS ≥9. Patients with SSS >4 were compared to patients with SSS <4. Parameters such as age, body mass index, waist perimeter, smoking habits, and medical history (diabetes mellitus, dyslipidemia, etc) were evaluated according to MPI results. Results: Myocardial ischemia was present in 32 (62%) of 52 patients with stroke. Among them, 20 (62%) of 32 patients had mild abnormalities and 12 (38%) of 32 had moderate/severe. The age and waist perimeter showed a tendency to relate to severe MIS when patients with SSS >9 were compared to patients with SSS <4. In MPI-positive patients, an age was to be association with SSS, with the oldest age exhibiting the highest SSS ( P = .01). The association of age with SSS remained statistically significant in the multivariate analysis ( P = .04). Conclusion: The study suggested that more than half of patients with stroke without a history of cardiac disease have MIS. Although most of them have mild MIS, we suggest a thorough cardiological evaluation in this group of patients for future prevention of severe myocardial outcome.

Sign in / Sign up

Export Citation Format

Share Document