scholarly journals Micronodular basal cell carcinoma of the scrotum- a case report and review of the literature

2021 ◽  
Author(s):  
Mohammad Younes ◽  
Lamia Kouba ◽  
Hanaa Almsokar ◽  
Ayham Badran
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Excisional Biopsy ◽  
Histological Subtypes ◽  
Main Risk Factor ◽  
Case Presentation ◽  
Exposed Skin ◽  
First Case ◽  
Ultraviolet Radiation Exposure

Abstract Introduction: Basal cell carcinoma (BCC) is the most common non-melanotic skin cancer. It has variable clinical and histological subtypes that vary in their aggressiveness and liability to recurrence and metastasis. Chronic ultraviolet radiation exposure is considered to be the main risk factor for developing BCC; therefore it typically arises on sun-exposed skin, mainly the head and neck. Case presentation: We present the case of a 55-year-old male who presented with a lesion on the scrotum for 2 years. The lesion was clinically presumed benign and initially treated with curettage. Microscopic examination revealed an incompletely resected micronodular BCC with sebaceous differentiation. Therefore, a second excisional biopsy was performed to completely excise the incidentally-discovered malignant tumor. Conclusion: We report the first case of micronodular BCC arising on the scrotum. The goal of our article is to draw clinicians’ attention to the possible involvement of unexposed skin with BCC and we highlight the importance of accurate diagnosis and prompt treatment due the aggressive nature of micronodular BCC.

scholarly journals Micronodular basal cell carcinoma of the scrotum: a case report and review of the literature

2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Mohammad Younes ◽  
Lamia Kouba ◽  
Hanaa Almsokar ◽  
Ayham Badran
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Excisional Biopsy ◽  
Histological Subtypes ◽  
Main Risk Factor ◽  
Case Presentation ◽  
Exposed Skin ◽  
First Case ◽  
Ultraviolet Radiation Exposure

Abstract Introduction Basal cell carcinoma is the most common nonmelanotic skin cancer. It has variable clinical and histological subtypes that vary in their aggressiveness and liability to recurrence and metastasis. Chronic ultraviolet radiation exposure is considered to be the main risk factor for developing basal cell carcinoma; therefore, it typically arises on sun-exposed skin, mainly the head and neck. Case presentation We present the case of a 55-year-old Caucasian male who presented with a lesion on the scrotum for 2 years. The lesion was clinically presumed benign and initially treated with curettage. Microscopic examination revealed an incompletely resected micronodular basal cell carcinoma with sebaceous differentiation. Therefore, a second excisional biopsy was performed to completely excise the incidentally discovered malignant tumor. Conclusion We report the first case of micronodular basal cell carcinoma arising on the scrotum. The goal of our article is to draw clinicians’ attention to the possible involvement of unexposed skin with basal cell carcinoma, and we highlight the importance of accurate diagnosis and prompt treatment due to the aggressive nature of micronodular basal cell carcinoma.

Susceptibility to Basal Cell Carcinoma is Associated with High Dermal Mast Cell Prevalence in Non–sun-exposed Skin for an Australian Population¶

2003 ◽  
Vol 78 (6) ◽  
pp. 633 ◽  
Author(s):  
Michele A. Grimbaldeston ◽  
Adele Green ◽  
Steven Darlington ◽  
Bryan O. Robertson ◽  
Gillian Marshman ◽  
...  
Keyword(s):  
Mast Cell ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Australian Population ◽  
Exposed Skin

scholarly journals Differences in age and topographic distribution of the different histological subtypes of basal cell carcinoma, Taubaté (SP), Brazil

2013 ◽  
Vol 88 (5) ◽  
pp. 726-730 ◽  
Author(s):  
Flavia Regina Ferreira ◽  
Bruna da Costa Pevide ◽  
Rafaela Fabri Rodrigues ◽  
Luiz Fernando Costa Nascimento ◽  
Marcia Lanzoni de Alvarenga Lira
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Skin Color ◽  
Age Of Onset ◽  
The Body ◽  
University Hospital ◽  
Histological Subtype ◽  
Histological Subtypes ◽  
The Mean

BACKGROUND: Basal cell carcinoma is the most common form of cancer in humans. OBJECTIVES: To identify the epidemiology of basal cell carcinoma in Taubaté-SP and verify a possible association between topography and the different histological subtypes of this tumor. METHODS: This was a cross-sectional study conducted at The University Hospital of Taubaté between 01/01/08 and 12/31/09. The study included patients with a confirmed diagnosis of basal cell carcinoma, of both genders, without age restrictions. The variables studied were incidence of basal cell carcinoma, topography, histological subtype, skin color, age and gender. We employed the chi-square test to identify the association between histological subtype and topography, and the student's t test to compare the mean age of onset for the different histological subtypes. RESULTS: The study included 239 individuals. The mean age of the sample was 68.0 years. Male subjects (57.7%) and whites (87.1%) predominated in the study. The predominant histological subtype was nodular (34.7%), followed by the superficial subtype. The most frequent sites of involvement were the head and neck (areas exposed to light), with predominance of the nasal region. The superficial subtype was an exception, as it showed a strong association with unexposed areas like the trunk. The mean age of onset of superficial basal cell carcinoma also differed from that of the other histological subtypes, 63.0 and 69.0 years, respectively. CONCLUSION: The results of this study suggest an association of the superficial histological subtype with younger patients and unexposed areas of the body, linking this type of tumor with a pattern of intermittent sun exposure, more similar to the standard photocarcinogenesis of melanoma.

scholarly journals Imiquimod triggering varicella zoster reactivation in an immunocompetent patient

2017 ◽  
Vol 6 (4) ◽  
pp. 990
Author(s):  
Thomas Jonathan Stewart ◽  
Andrea Tomizawa ◽  
Robert Rosen
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Immunocompetent Patient ◽  
Varicella Zoster ◽  
First Case ◽  
Superficial Basal Cell Carcinoma

Imiquimod is widely used for the treatment of superficial basal cell carcinoma as well as several other dermatologic conditions. While its local immunostimulatory action is well proven, its potential for systemic immunomodulation has been less well described. We report the first case (to our knowledge) of varicella zoster reactivation caused by Imiquimod in an immunocompetent patient. 

scholarly journals Upfront Radiotherapy with Concurrent and Adjuvant Vismodegib Is Effective and Well-Tolerated in a Patient with Advanced, Multifocal Basal Cell Carcinoma

2018 ◽  
Vol 2018 ◽  
pp. 1-4 ◽  
Author(s):  
Abigail I. Franco ◽  
Gary Eastwick ◽  
Ramsay Farah ◽  
Marvin Heyboer ◽  
Mijung Lee ◽  
...  
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Complete Response ◽  
Combined Modality Treatment ◽  
Tumor Infiltration ◽  
Concurrent Treatment ◽  
Large Size ◽  
First Case ◽  
Fractionated Radiation

We present a case report of a male with multifocal and extensive basal cell carcinoma. Due to extremely large size and deep tumor infiltration, he was not a surgical candidate. Combined modality treatment of fractionated radiation with concurrent vismodegib was chosen. Concurrent treatment was previously reported in the palliative and recurrent setting. This is the first case of concurrent vismodegib and radiation therapy for upfront definitive management. The patient experienced complete response in all treated lesions.

scholarly journals Histological subtypes of periocular basal cell carcinoma

2014 ◽  
Vol 42 (7) ◽  
pp. 603-607 ◽  
Author(s):  
Albert Wu ◽  
Michelle T Sun ◽  
Shyamala C Huilgol ◽  
Simon Madge ◽  
Dinesh Selva
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Histological Subtypes
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