Optoflow: Design Tools for Integrating Optical Detection in Micro-Total Analysis Systems

2004 ◽  
Author(s):  
Tom Korsmeyer
Keyword(s):  
Optical Detection ◽  
Design Tools ◽  
Micro Total Analysis Systems ◽  
Total Analysis

scholarly journals Glass based Micro Total Analysis Systems: Materials, Fabrication methods, and Applications

2021 ◽  
pp. 129859
Author(s):  
Tao Tang ◽  
Yapeng Yuan ◽  
Yaxiaer Yalikun ◽  
Yochiroh Hosokawa ◽  
Ming Li ◽  
...  
Keyword(s):  
Micro Total Analysis Systems ◽  
Total Analysis

Three-Dimensional CFD Model of Pressure Drop in µTAS Devices in a Microchannel

2011 ◽  
Vol 133 (3) ◽  
Author(s):  
Damena D. Agonafer ◽  
J. Yeom ◽  
M. A. Shannon
Keyword(s):  
Pressure Drop ◽  
Figure Of Merit ◽  
Flow Resistance ◽  
Three Dimensional ◽  
Design Rule ◽  
Dynamics Model ◽  
Enhance Heat Transfer ◽  
Micro Total Analysis Systems ◽  
Total Analysis ◽  
Adsorption Desorption

Microposts are utilized to enhance heat transfer, adsorption/desorption, and surface chemical reactions. In a previous study [Yeom et al., J. Micromech. Microeng., 19, p. 065025 (2009)], based in part on an experimental study, an analytical expression was developed to predict the pressure drop across a microchannel filled with arrays of posts with the goal of fabricating more efficient micro-total analysis systems (µTAS) devices for a given pumping power. In particular, a key figure of merit for the design of micropost-filled reactors, based on the flow resistance models was reported thus providing engineers with a design rule to develop efficient µTAS devices. The study did not include the effects of the walls bounding the microposts. In this paper, a three-dimensional computational fluid dynamics model is used to include the effects of three-dimensionality brought about by the walls of the µTAS devices that bound the microposted structures. In addition, posts of smaller size that could not be fabricated for the experiments were also included. It is found that the two- and three-dimensional effects depend on values of the aspect ratio and the blockage ratios. The Reynolds number considered in the experiment that ranged from 1 to 10 was extended to 300 to help determine the range of Re for which the FOM model is applicable.

Design Techniques for Microfluidic Devices Implementation Applicable to Chemical Analysis Systems

2019 ◽  
pp. 195-222 ◽  
Author(s):  
Reinaldo Lucas dos Santos Rosa ◽  
Antonio Carlos Seabra
Keyword(s):  
Chemical Analysis ◽  
Solid Phase ◽  
Microfluidic Devices ◽  
Water Quality Monitoring ◽  
Analysis Process ◽  
Micro Total Analysis Systems ◽  
Total Analysis ◽  
On Chip ◽  
Separation Cell ◽  
High Level

This chapter provides a guide for microfluidic devices development and optimization focused on chemical analysis applications, which includes medicine, biology, chemistry, and environmental monitoring, showing high-level performance associated with a specific functionality. Examples are chemical analysis, solid phase extraction, chromatography, immunoassay analysis, protein and DNA separation, cell sorting and manipulation, cellular biology, and mass spectrometry. In this chapter, most information is related to microfluidic devices design and fabrication used to perform several steps concerning chemical analysis, process preparation of reagents, samples reaction and detection, regarding water quality monitoring. These steps are especially relevant to lab-on-chip (LOC) and micro-total-analysis-systems (μTAS). μTAS devices are developed in order to simplify analytical chemist work, incorporating several analytical procedures into flow systems. In the case of miniaturized devices, the analysis time is reduced, and small volumes (nL) can be used.

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