Metabolomic and Lipidomic Profiling of Plasma and Cyst Fluid Allows the Detection and Characterization of Pancreatic Intraductal Papillary Mucinous Neoplasms

2018 ◽  
Author(s):  
Rogier Gaiser ◽  
Alberto Pessia ◽  
Zeeshan Ateeb ◽  
Haleh Davanian ◽  
Carlos Fernández Moro ◽  
...  
Keyword(s):  
Cyst Fluid ◽  
Intraductal Papillary Mucinous Neoplasms ◽  
Mucinous Neoplasms

Cytological and Cyst Fluid Analysis of Small (≤3 cm) Branch Duct Intraductal Papillary Mucinous Neoplasms Adds Value to Patient Management Decisions

Pancreatology ◽  
2008 ◽  
Vol 8 (3) ◽  
pp. 277-284 ◽  
Author(s):  
Martha Bishop Pitman ◽  
Paul J. Michaels ◽  
Vikram Deshpande ◽  
William R. Brugge ◽  
Brenna C. Bounds
Keyword(s):  
Patient Management ◽  
Cyst Fluid ◽  
Management Decisions ◽  
Intraductal Papillary Mucinous Neoplasms ◽  
Branch Duct ◽  
Fluid Analysis ◽  
Mucinous Neoplasms

scholarly journals Cyst Fluid Biosignature to Predict Intraductal Papillary Mucinous Neoplasms of the Pancreas with High Malignant Potential

2019 ◽  
Vol 228 (5) ◽  
pp. 721-729 ◽  
Author(s):  
Ajay V. Maker ◽  
Vincent Hu ◽  
Shrihari S. Kadkol ◽  
Lenny Hong ◽  
William Brugge ◽  
...  
Keyword(s):  
Malignant Potential ◽  
Cyst Fluid ◽  
Intraductal Papillary Mucinous Neoplasms ◽  
Mucinous Neoplasms

Characterization of K-ras gene mutations in association with mucinous hypersecretion in intraductal papillary-mucinous neoplasms

2008 ◽  
Vol 15 (2) ◽  
pp. 169-177 ◽  
Author(s):  
Noritoshi Kobayashi ◽  
Masahiko Inamori ◽  
Koji Fujita ◽  
Toshio Fujisawa ◽  
Nobutaka Fujisawa ◽  
...  
Keyword(s):  
Gene Mutations ◽  
Ras Gene ◽  
Intraductal Papillary Mucinous Neoplasms ◽  
Mucinous Neoplasms

scholarly journals Pancreatic Cyst Fluid and Serum Mucin Levels Predict Dysplasia in Intraductal Papillary Mucinous Neoplasms of the Pancreas

2010 ◽  
Vol 18 (1) ◽  
pp. 199-206 ◽  
Author(s):  
Ajay V. Maker ◽  
Nora Katabi ◽  
Mithat Gonen ◽  
Ronald P. DeMatteo ◽  
Michael I. D’Angelica ◽  
...  
Keyword(s):  
Pancreatic Cyst ◽  
Cyst Fluid ◽  
Intraductal Papillary Mucinous Neoplasms ◽  
Mucinous Neoplasms ◽  
Pancreatic Cyst Fluid

scholarly journals Stratifying Intraductal Papillary Mucinous Neoplasms by Cyst Fluid Analysis: Present and Future

2020 ◽  
Vol 21 (3) ◽  
pp. 1147
Author(s):  
Scarlett Hao ◽  
Caitlin Takahashi ◽  
Rebecca A. Snyder ◽  
Alexander A. Parikh
Keyword(s):  
Significant Proportion ◽  
Cyst Fluid ◽  
Low Risk ◽  
Intraductal Papillary Mucinous Neoplasms ◽  
Radiographic Findings ◽  
Genetic Sequencing ◽  
Perioperative Morbidity ◽  
Fluid Analysis ◽  
Mucinous Neoplasms ◽  
Risk Of Malignancy

A significant proportion of patients with intraductal papillary mucinous neoplasms (IPMNs) undergo surgical resection in order to prevent or treat pancreatic cancer at the risk of significant perioperative morbidity. Efforts have been made to stratify the potential risk of malignancy based on the clinical and radiographic features of IPMN to delineate which cysts warrant resection versus observation. An analysis of the cyst fluid obtained by preoperative endoscopic examination appears to be correlative of cyst type and risk, whereas serum markers and radiographic findings have not yet reached a level of sensitivity or specificity that proves they are clinically meaningful. In this review, we investigate the current cyst fluid analysis studies and present those that have shown promise in effectively stratifying high-risk versus low-risk lesions. While new cyst fluid markers continue to be identified, additional efforts in testing panels and marker composites in conjunction with clinical algorithms have also shown promise in distinguishing dysplasia and the risk of malignancy. These should be tested prospectively in order to determine their role in guiding the surveillance of low-risk lesions and to evaluate the new markers detected by proteomics and genetic sequencing.

scholarly journals Sa1443 CYST FLUID CARCINOEMBRYONIC ANTIGEN DIFFERENCE AMONG MUCINOUS CYSTIC NEOPLASMS AND INTRADUCTAL PAPILLARY MUCINOUS NEOPLASMS

2020 ◽  
Vol 91 (6) ◽  
pp. AB192-AB193
Author(s):  
Ibrahim H. Köker ◽  
Nurcan Ünver ◽  
Fatma U. Malya ◽  
Ömer Uysal ◽  
Hakan Senturk
Keyword(s):  
Carcinoembryonic Antigen ◽  
Cyst Fluid ◽  
Intraductal Papillary Mucinous Neoplasms ◽  
Cystic Neoplasms ◽  
Mucinous Cystic Neoplasms ◽  
Mucinous Neoplasms
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