Characterization of K-ras gene mutations in association with mucinous hypersecretion in intraductal papillary-mucinous neoplasms

2008 ◽  
Vol 15 (2) ◽  
pp. 169-177 ◽  
Author(s):  
Noritoshi Kobayashi ◽  
Masahiko Inamori ◽  
Koji Fujita ◽  
Toshio Fujisawa ◽  
Nobutaka Fujisawa ◽  
...  
Keyword(s):  
Gene Mutations ◽  
Ras Gene ◽  
Intraductal Papillary Mucinous Neoplasms ◽  
Mucinous Neoplasms

Characterization of CD24 expression in intraductal papillary mucinous neoplasms and ductal carcinoma of the pancreas

2010 ◽  
Vol 41 (10) ◽  
pp. 1466-1474 ◽  
Author(s):  
Naoki Ikenaga ◽  
Kenoki Ohuchida ◽  
Kazuhiro Mizumoto ◽  
Jun Yu ◽  
Tadashi Kayashima ◽  
...  
Keyword(s):  
Ductal Carcinoma ◽  
Intraductal Papillary Mucinous Neoplasms ◽  
Carcinoma Of The Pancreas ◽  
Mucinous Neoplasms

scholarly journals Diagnosis of the pancreatic cancer

2021 ◽  
Vol 11 (9) ◽  
pp. 67-73
Author(s):  
Przemysław Raczkiewicz ◽  
Maria Kalicka ◽  
Tomasz Korzec ◽  
Konrad Kania ◽  
Katarzyna Cyboran
Keyword(s):  
Pancreatic Cancer ◽  
Pancreatic Cyst ◽  
Precancerous Lesions ◽  
Gene Mutations ◽  
Intraepithelial Neoplasia ◽  
Key Words Pancreatic Cancer ◽  
Intraductal Papillary Mucinous Neoplasms ◽  
Cystic Neoplasms ◽  
Non Invasive ◽  
Mucinous Neoplasms

Introduction: The pancreatic cancer arises from non-invasive precursor lesions and develops through the accumulation of characteristic gene mutations. The recent scientific reports based on genetic tests state that the approximate time between cancerous initiation and the development of cancer with metastasisis15 years. We candistinguish three main precancerous lesions leading to the pancreatic cancer: pancreatic intraepithelial neoplasia (PanIN), mucinous cystic neoplasms (MCN), and intraductal papillary mucinous neoplasms (IPMN). The imaging tests used for the diagnostics and observation of precancerous pancreas lesions are MR, MRC, CT and EUS. Method: review of the recent literature based on PubMEd, Google scholar research based onthe following key words: pancreatic cancer, precancer of the pancreas, pancreatic cyst, tuber of the pancreas, medical imaging of the pancreasPurpose of the work: systematizing information about precancers of the pancreatic cancer based on the latest research and findings

scholarly journals Molecular characterization of organoids derived from pancreatic intraductal papillary mucinous neoplasms

2020 ◽  
Vol 252 (3) ◽  
pp. 252-262 ◽  
Author(s):  
Bo Huang ◽  
Maria A Trujillo ◽  
Kohei Fujikura ◽  
Miaozhen Qiu ◽  
Fei Chen ◽  
...  
Keyword(s):  
Molecular Characterization ◽  
Intraductal Papillary Mucinous Neoplasms ◽  
Mucinous Neoplasms

Intestinal Heterotopic Pancreas Involved by Simultaneous PanIN-2 Lesion and Endocrine Microadenoma: a Unique Case

2017 ◽  
Vol 26 (2) ◽  
pp. 199-202
Author(s):  
Remus Cornea ◽  
Sorina Taban ◽  
Cristian Suciu ◽  
Codruta Lazureanu ◽  
Alis Dema
Keyword(s):  
Histopathological Examination ◽  
Intraepithelial Neoplasia ◽  
Heterotopic Pancreas ◽  
Pancreatic Intraepithelial Neoplasia ◽  
Unique Case ◽  
Intraductal Papillary Mucinous Neoplasms ◽  
Pancreatic Endocrine Neoplasm ◽  
First Case ◽  
Mucinous Neoplasms

We hereby present the case of a 58-year-old male who underwent a total gastrectomy for gastric neoplasm. During the surgery, a tumor mass in the jejunum was identified, considered as metastasis, and resected. The histopathological examination of the jejunal lesion showed ectopic pancreas. In this area, two pathological distinct lesions were identified, one histologically compatible with pancreatic intraepithelial neoplasia (PanIN) type 2 lesion and the other with morphologic criteria for endocrine microadenoma. To our knowledge, this is the first case that evidences the presence of a concomitant premalignant exocrine lesion and benign endocrine lesion in a heterotopic pancreas (HP).Abbreviations: HP: heterotopic pancreas; IPMN: Intraductal Papillary Mucinous Neoplasms; PanIN: Pancreatic Intraepithelial Neoplasia; PEN: pancreatic endocrine neoplasm.

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