Dynamic Interaction of USP14 with the Chaperone HSC70 Mediates Crosstalk between Proteaseome, ER Signaling and Autophagy

2019 ◽  
Author(s):  
Vignesh Srinivasan ◽  
Céline Bruelle ◽  
Enzo Scifo ◽  
Dan Duc Pham ◽  
Rabah Soliymani ◽  
...  
Keyword(s):  
Vestnik MEI ◽  
2019 ◽  
Vol 5 ◽  
pp. 11-23
Author(s):  
Konstantin N. Proskuryakov ◽  

2001 ◽  
Vol 76 (1) ◽  
pp. 59-80 ◽  
Author(s):  
D. Paul Newman ◽  
Evelyn Patterson ◽  
Reed Smith

We consider how auditors assess the risk of fraudulent financial reporting and plan their audit where a possibly fraudulent auditee anticipates the assessment and planning process. The auditor uses the auditee's (possibly fraudulent) earnings report to revise his beliefs about the likelihood of fraud when formulating an audit plan. We find that as underlying earnings increase, a fraudulent auditee increases reported earnings. In turn, as the auditee's reported earnings increase, the auditor increases audit effort. We also find that the auditee (who knows the auditor will use the report for audit planning) selects reports that increase his own expected payoff, relative to reports he would select if the auditor did not observe the report before finalizing the audit plan. By contrast, the auditor is no better off using the auditee's report for audit planning. Inherent risk, detection risk, and overall audit risk can increase when the auditor uses the auditee's report. Thus, because of the dynamic interaction between the auditor and auditee, procedures that aid in assessing audit risk may not reduce that risk or result in more efficient audits.


2020 ◽  
Vol 65 (9) ◽  
pp. 326-332
Author(s):  
N. F. Morozov ◽  
D. A. Indeitsev ◽  
A. V. Lukin ◽  
I. A. Popov ◽  
O. V. Privalova ◽  
...  
Keyword(s):  

Author(s):  
Timothy Matovina

Our Lady of Guadalupe is the only Marian apparition tradition in the Americas—and indeed in all of Roman Catholicism—that inspired a sustained series of published theological analyses. Theologians in each successive epoch since the mid-seventeenth century have plumbed the meaning of Guadalupe for their times. Their theological works are grounded in two realities: the first is the relationship between Guadalupe and her faithful, and the second is her power to shape their lives and their world. Theologies of Guadalupe examines the way theologians have understood Guadalupe and sought to orient her impact in the lives of her devotees. It also examines Guadalupe’s meaning in everyday devotees’ lives and the spread of Guadalupan devotion over nearly half a millennium. Chapters of this study successively examine core theological topics in the Guadalupe tradition developed in response to major events of Mexican history: conquest, attempts to Christianize native peoples, society building, independence, and the demands for justice of marginalized groups. The successive chapters also narrate how, amid the plentiful miraculous images of Christ, Mary, and the saints that dotted the sacred landscape of colonial New Spain, the Guadalupe cult rose above all others and emerged from a local devotion to become a regional, national, and then international phenomenon. From patristic-based theological writings in the colonial era down to contemporary formulations shaped by the emergence of liberation theologies in Latin America, the theologies under study here reveal how Christian concepts and scriptures imported from Europe developed in dynamic interaction with the new contexts in which they took root.


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