DAMPAK PENGGUNAAN BETAHISTIN MESILATE TERHADAP PERBAIKAN GEJALA VERTIGO PERIFER DI RUMAH SAKIT BETHESDA YOGYAKARTA

2017 ◽  
Vol 2 (3) ◽  
pp. 427
Author(s):  
Kristina Reny Indriawati ◽  
Rizaldy Taslim Pinzon
Keyword(s):  
Case Series ◽  
Dizziness Handicap Inventory

Vertigo adalah salah satu keluhan yang sering dijumpai dalam praktek yang digambarkan sebagai rasa berputar, pening, tak stabil (giddiness, unsteadiness) atau pusing (dizziness). Penatalaksanaan pasien-pasien vertigo perifer sering kontroversi karena patofisiologi vertigo belum jelas. Beberapa obat ditemukan memiliki aktivitas antivertigo. Betahistin menyerupai histamin untuk terapi gangguan vaskuler dan vasomotor, dipakai untuk pengobatan vertigo, motionsickness, dan gangguan vestibuler sentral atau perifer. Mengetahui dampak penggunaan betahistin mesilate terhadap perbaikan gejala vertigo perifer di Rumah Sakit Bethesda Yogyakarta.Non eksperimental menggunakan rancangan case series dan menggunakan data prospektif. Untuk mengidentifikasi perbedaan dampak penggunaan betahistin pada penderita vertigo perifer, dengan perbaikan derajat keluhan vertigo digunakan skala Dizziness Handicap Inventory (DHI). Sebanyak 20 subyek penelitian yang masuk kriteria inklusi dianalisis menggunakan uji repeated ANOVA. Data diperoleh dari 20 pasien dengan vertigo perifer didapatkan rerata total skor DHI pada baseline (awal) adalah 42,95±21,44, 35,20±19,56 pada kunjungan 2, dan 28,40±18,76 pada kunjungan 3 didapatkan signifikansi (p) sebesar 0,000. Rerata skor item DHI pada baseline (awal), kunjungan 2, dan kunjungan 3 pada item fisik (14,30±9,02 versus 13,00±8,14 versus 10,20±6,55), item fungsional (17,55±8,77 versus 13,40±7,43 versus 11,20±7,00), dan item emosional (11,10±8,06 versus 8,80±7,82 versus 7,10±7,77) didapatkan p<0,001. Penggunaan betahistin masilate memperbaiki gejala vertigo perifer

Predicting the Outcome after Acute Unilateral Vestibulopathy: Analysis of Vestibulo-ocular Reflex Gain and Catch-up Saccades

2017 ◽  
Vol 158 (3) ◽  
pp. 527-533 ◽  
Author(s):  
Niccolò Cerchiai ◽  
Elena Navari ◽  
Stefano Sellari-Franceschini ◽  
Chiara Re ◽  
Augusto Pietro Casani
Keyword(s):  
High Velocity ◽  
Case Series ◽  
Vestibular Rehabilitation ◽  
Rehabilitation Program ◽  
Head Impulse Test ◽  
Dizziness Handicap Inventory ◽  
Reflex Gain ◽  
Catch Up ◽  
Unilateral Vestibulopathy ◽  
Acute Unilateral Vestibulopathy

Objectives (1) To describe the relationships among the main instrumental features characterizing an acute unilateral vestibulopathy and (2) to clarify the role of the video head impulse test in predicting the development of chronic vestibular insufficiency. Study Design Case series with chart review. Setting Tertiary referral center. Subjects and Methods Sixty patients suffering from acute unilateral vestibulopathy were retrospectively analyzed: 30 who recovered spontaneously (group 1) and 30 who needed a vestibular rehabilitation program (group 2). The main outcome measures included Dizziness Handicap Inventory score, canal paresis, high-velocity vestibulo-oculomotor reflex gain, and catch-up saccade parameters. The tests were all performed between 4 and 8 weeks from the onset of symptoms. Results The high-velocity vestibulo-oculomotor reflex gain correlated with the Dizziness Handicap Inventory score ( P = .004), with the amplitude of covert and overt saccades ( P < .001), and with the prevalence of overt saccades ( P < .001). Patients in need for vestibular rehabilitation programs had a significantly lower gain ( P < .001) and a higher prevalence and amplitude of overt saccades ( P = .002 and P = .008, respectively). Conversely, we found no differences in terms of response to the caloric test ( P = .359). Conclusions Lower values of high-velocity vestibulo-oculomotor reflex gain and a high prevalence of overt saccades are related to a worse prognosis after acute unilateral vestibulopathy. This is of great interest to clinicians in identifying which patients are less likely to recover and more likely to need a vestibular rehabilitation program.

scholarly journals Imipramine for vestibular dysfunction in panic disorder: a prospective case series

2011 ◽  
Vol 69 (2a) ◽  
pp. 196-201 ◽  
Author(s):  
Marco Andre Mezzasalma ◽  
Kátia de Vasconcellos Mathias ◽  
Isabella Nascimento ◽  
Alexandre M. Valença ◽  
Antonio E. Nardi
Keyword(s):  
Panic Disorder ◽  
Case Series ◽  
Dizziness Handicap Inventory ◽  
Chronic Dizziness ◽  
Hamilton Anxiety Scale ◽  
The Mean ◽  
Anxiety Levels ◽  
Prospective Case Series ◽  
The Impact

OBJECTIVE: The purpose of this study was to evaluate the efficacy and effectiveness of imipramine on the treatment of comorbid chronic dizziness and panic disorder. METHOD: Nine patients with panic disorder and agoraphobia associated with chronic dizziness underwent otoneurological screening and were treated with a 3-months course of imipramine. Anxiety levels were measured with the Hamilton Anxiety Scale (HAM-A), dizziness levels were evaluated using the Dizziness Handicap Inventory (DHI), and panic severity and treatment outcome were assessed with the Clinical Global Impression Scale (CGI). RESULTS: At the baseline 33.3% (n=3) had a bilateral peripheral deficit vestibulopathy, the mean scores for HAM-A were 27.2±10.4, for DHI were 51.7±22.7, and for CGI-S were 4.8±0.9. All patients had a significant reduction in their HAM-A (11.1±5.5, p=0.008), DHI (11.5±8.1, p=0.008) and CGI-I (1.8±0.7, p=0.011) levels after 3-months imipramine treatment (mean=72.2±23.2 mg/day). CONCLUSION: This study found a decrease in anxiety levels and in the impact of dizziness in the patients' quality of life after a 3-months treatment course with imipramine.

Abstract #856 A Case Series Review of Clinical and Biochemical Characteristics of Pituitary Abcess in Mexican Patients

2018 ◽  
Vol 24 ◽  
pp. 202-203
Author(s):  
Mireya Perez-Guzman ◽  
Alfredo Nava de la Vega ◽  
Arturo Pena Velarde ◽  
Tania Raisha Torres Victoria ◽  
Froylan Martinez-Sanchez ◽  
...  
Keyword(s):  
Case Series ◽  
Biochemical Characteristics ◽  
Mexican Patients

Cannabis-associated arteritis

VASA ◽  
2010 ◽  
Vol 39 (1) ◽  
pp. 43-53 ◽  
Author(s):  
Grotenhermen
Keyword(s):  
Systematic Review ◽  
Case Reports ◽  
Case Series ◽  
Cardiovascular Effects ◽  
Causative Factor ◽  
Cannabis Use ◽  
Thromboangiitis Obliterans ◽  
Pathological Features ◽  
Scientific Support ◽  
Clinical And Pathological Features

Background: To investigate the hypothesis that cases of arteritis similar to thromboangiitis obliterans (TAO) and associated with the use of cannabis were caused by cannabis or THC (dronabinol), or that cannabis use is a co-factor of TAO. Patients and methods: A systematic review on case reports and the literature on so-called cannabis arteritis, TAO, and cardiovascular effects of cannabinoids was conducted. Results: Fifteen reports with 57 cases of an arteritis associated with the use of cannabis and two additional case series of TAO, in which some patients also used cannabis, were identified. Clinical and pathological features of cannabis-associated arteritis do not differ from TAO and the major risk factor of TAO, tobacco use, was present in most, if not in all of these cases. The proposed pathophysiological mechanisms for the development of an arteritis by cannabis use are not substantiated. Conclusions: The hypothesis of cannabis being a causative factor or co-factor of TAO or an arteritis similar to TAO is not supported by the available evidence. The use of the term “cannabis arteritis” should be avoided until or unless more convincing scientific support is forthcoming.

Propranolol Weakens Trauma-Related Psychophysiological Arousal: A Case Series

2009 ◽  
Author(s):  
Emilie Thomas ◽  
Joaquin Poundja ◽  
Alain Brunet ◽  
Jacques Tremblay
Keyword(s):  
Case Series ◽  
Psychophysiological Arousal

Habituation of stress in psychotherapists performing subsequent in vivo exposures—A case series.

2017 ◽  
Vol 27 (2) ◽  
pp. 218-224 ◽  
Author(s):  
Sarah Schumacher ◽  
Felix Betzler ◽  
Robert Miller ◽  
Clemens Kirschbaum ◽  
Andreas Ströhle
Keyword(s):  
Case Series
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