scholarly journals Characteristics of Myocardial Perfusion in Type 2 Diabetes Mellitus and Its Association with Left Ventricular Diastolic Dysfunction: A Study of Myocardial Contrast Echocardiography

2021 ◽  
Vol Volume 14 ◽  
pp. 7533-7543
Author(s):  
Yi Liu ◽  
Jing Ma ◽  
Jia Guo ◽  
Hao Lu ◽  
Yan Zhang ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Myocardial Perfusion ◽  
Diastolic Dysfunction ◽  
Contrast Echocardiography ◽  
Left Ventricular Diastolic Dysfunction ◽  
Left Ventricular ◽  
Ventricular Diastolic Dysfunction

scholarly journals Echocardiographic evaluation of left ventricular diastolic dysfunction in recently diagnosed type 2 diabetes mellitus

2018 ◽  
Vol 6 (5) ◽  
pp. 1691
Author(s):  
Swapnil Jain ◽  
C. L. Nawal ◽  
Amandeep Singh ◽  
Radhey Shyam Chejara ◽  
Sagar Barasara ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Diastolic Dysfunction ◽  
Left Ventricular Diastolic Dysfunction ◽  
Left Ventricular ◽  
P Value ◽  
Diabetic Patients ◽  
Ventricular Diastolic Dysfunction

Background: Diastolic dysfunction in patients suffering from diabetes mellitus represents an earlier stage in the natural history of cardiomyopathy. This study was done to assess the left ventricular diastolic dysfunction in recently diagnosed (<5yr) Type 2 Diabetes Mellitus by Echocardiography and also to determine association of glycemic status (by HBA1c levels) with left ventricular diastolic dysfunction (LVDD).Methods: An observational descriptive study involving 100 diabetic patients, taken on first come first serve basis after applying inclusion and exclusion criteria. In all the subjects, other than routine investigations, HbA1c was estimated and echocardiography was done to evaluate LVDD.Results: Mean value of HbA1c in the study was 8.31+ 1.408 %. 63 out of 100 subjects had LVDD. There was significant positive correlation between HbA1c and LVDD (p value <0.001). As HbA1c increased, severity of LVDD increased. In this study, as BMI increased, HbA1c and LVDD increased & both findings were statistically significant (p value =0.001).Conclusion: Our study indicates that myocardial damage in patients with diabetes affects diastolic function before systolic function &higher HbA1C level is strongly associated with presence of LVDD. Patients should be advised strict control of diabetes in order to reduce the risk for developing LVDD which is a precursor for more advanced disease.Keywords: Diabetes mellitus, Diastolic dysfunction, BMI, HbA1c

scholarly journals Left ventricular diastolic dysfunction in asymptomatic type 2 diabetes mellitus patients

2017 ◽  
Vol 6 (1) ◽  
pp. 240
Author(s):  
Karan Jain ◽  
Amit A. Palange ◽  
Arjun Lal Kakrani ◽  
Akshay S. Dhanorkar
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Diastolic Dysfunction ◽  
Ventricular Dysfunction ◽  
Left Ventricular Diastolic Dysfunction ◽  
Left Ventricular ◽  
Muscle Disease ◽  
Ventricular Diastolic Dysfunction

Background: Diastolic dysfunction has been described as an early sign of diabetic heart muscle disease preceding the systolic damage. The pathogenesis of ventricular dysfunction remains unknown and has been somewhat controversial. So far, very few population-based studies have been carried out in India, to demonstrate the prevalence of diastolic dysfunction in diabetic subjects. Hence the present study was done at our tertiary care centre to detect left diastolic dysfunction in asymptomatic type 2 diabetes individuals and to use echo-cardiologic assessment as an early detector of left diastolic dysfunction. The aim of this study was to detect left diastolic dysfunction in asymptomatic type 2 diabetes individuals and to use echocardiologic assessment as an early detector of left diastolic dysfunction.Methods: A hospital based cross-sectional observational study was conducted with 50 patients for echocardiographic evaluation of diastolic dysfunction in asymptomatic Type 2 Diabetes Mellitus. E/A <1 and increase in LA size was considered as the evidence of left ventricular Diastolic Dysfunction.Results: 15 (30%) patients were detected with Left Ventricular Diastolic Dysfunction (LVDD) among the 50 patients under study.Conclusions: Diastolic dysfunction in patients with diabetes is present in 30% of patients even when diabetes is present at a younger age, and is of a shorter duration. This dysfunction is suggestive of pre-clinical diabetic cardiomyopathy. E/A, DT and peak A velocity are sensitive indices of diastolic LV dysfunction. Thus, diastolic dysfunction can be used as an early indicator, as it is a precursor to increased LV hypertrophy and clinical left ventricular dysfunction.

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