scholarly journals Linear polyethylenimine produced by partial acid hydrolysis of poly(2-ethyl-2-oxazoline) for DNA and siRNA delivery in vitro

2013 ◽  
pp. 4091 ◽  
Author(s):  
Qin Shi ◽  
Julio Fernandes ◽  
Qiu ◽  
Zhang ◽  
Dai ◽  
...  

1957 ◽  
Vol 79 (10) ◽  
pp. 2559-2565 ◽  
Author(s):  
N. J. Hipp ◽  
M. L. Groves ◽  
T. L. McMeekin


2012 ◽  
Vol 7 (11) ◽  
pp. 1934578X1200701 ◽  
Author(s):  
Zonghong Li ◽  
Dan Jiang ◽  
Hongtao Bi ◽  
Dazheng Liu ◽  
Sungju Jang ◽  
...  

A glucuronomannan (AA-4-H, Mw around 4 KDa) was prepared from the fruit bodies of Auricularia auricala by extraction with hot water, deproteination by Sevag reagent, stepwise precipitation with ethanol and partial acid hydrolysis. Monosaccharides analysis revealed that AA-4-H consisted of 91% mannose (Man) and 9% glucuronic acid (GlcA). FT-IR, NMR and methylation analyses indicated that AA-4-H is a branched glucuronomannan. Its main chains are composed of 1, 3-linked α-Man p, side chains are single α-Man p or α-GlcA residues attached to the O-2 and O-6 of Man residues of the main chains. Bioassay indicated that AA-4-H remarkably enhanced B lymphocyte proliferation and increased the production of nitric oxide of macrophages in vitro. Thus, glucuronomannan AA-4-H could be explored as a potential immunostimulation agent.







1949 ◽  
Vol 44 (5) ◽  
pp. 548-560 ◽  
Author(s):  
R. Consden ◽  
A. H. Gordon ◽  
A. J. P. Martin


2016 ◽  
Vol 129 ◽  
pp. 427-432 ◽  
Author(s):  
Marina C. Nemitz ◽  
Jaqueline N. Picada ◽  
Juliana da Silva ◽  
Ana Letícia H. Garcia ◽  
Débora K.M. Papke ◽  
...  


Molecules ◽  
2020 ◽  
Vol 25 (23) ◽  
pp. 5542
Author(s):  
Adrian Wiater ◽  
Adam Waśko ◽  
Paulina Adamczyk ◽  
Klaudia Gustaw ◽  
Małgorzata Pleszczyńska ◽  
...  

Increasing knowledge of the role of the intestinal microbiome in human health and well-being has resulted in increased interest in prebiotics, mainly oligosaccharides of various origins. To date, there are no reports in the literature on the prebiotic properties of oligosaccharides produced by the hydrolysis of pure fungal α-(1→3)-glucan. The aim of this study was to prepare α-(1→3)-glucooligosaccharides (α-(1→3)-GOS) and to perform initial evaluation of their prebiotic potential. The oligosaccharides were obtained by acid hydrolysis of α-(1→3)-glucan isolated from the fruiting bodies of Laetiporus sulphureus and then, characterized by HPLC. Fermentation of α-(1→3)-GOS and reference prebiotics was compared in in vitro pure cultures of Lactobacillus, Bifidobacterium, and enteric bacterial strains. A mixture of α-(1→3)-GOS, notably with a degree of polymerization of 2 to 9, was obtained. The hydrolysate was utilized for growth by most of the Lactobacillus strains tested and showed a strong bifidogenic effect, but did not promote the growth of Escherichia coli and Enterococcus faecalis. α-(1→3)-GOS proved to be effective in the selective stimulation of beneficial bacteria and can be further tested to determine their prebiotic functionality.



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