scholarly journals A new surgical strategy for the intractable chronic low back pain due to type 1 Modic change using transforaminal full-endoscopic disc cleaning (FEDC) surgery under the local anesthesia : A case report and literature review

2021 ◽  
Vol 68 (1.2) ◽  
pp. 1-5
Author(s):  
Koichi Sairyo ◽  
Toru Maeda ◽  
Kazuta Yamashita ◽  
Fumitake Tezuka ◽  
Masatoshi Morimoto ◽  
...  
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Case Report ◽  
Literature Review ◽  
Local Anesthesia ◽  
Chronic Low Back Pain ◽  
Surgical Strategy ◽  
Low Back ◽  
Modic Change

scholarly journals Necrotizing fasciitis likely mistaken for chronic low back pain - A case report -

2018 ◽  
Vol 13 (3) ◽  
pp. 298-301
Author(s):  
So Hui Yun ◽  
Jong Cook Park ◽  
You Jin Kim
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Case Report ◽  
Necrotizing Fasciitis ◽  
Chronic Low Back Pain ◽  
Low Back

scholarly journals The effect of infliximab in patients with chronic low back pain and Modic changes (the BackToBasic study): study protocol of a randomized, double blind, placebo-controlled, multicenter trial

2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Elisabeth Gjefsen ◽  
Lars Christian Haugli Bråten ◽  
Guro Løvik Goll ◽  
Monica Wigemyr ◽  
Nils Bolstad ◽  
...  
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Chronic Low Back Pain ◽  
Treatment Strategy ◽  
Treatment Options ◽  
Modic Changes ◽  
Low Back ◽  
Double Blind ◽  
Link Type

Abstract Background Low back pain is common and a significant number of patients experience chronic low back pain. Current treatment options offer small to moderate effects. Patients with vertebral bone marrow lesions visualized as Modic changes on magnetic resonance imaging may represent a subgroup within the low back pain population. There is evidence for inflammatory mediators being involved in development of Modic changes; hence, suppression of inflammation could be a treatment strategy for these patients. This study examines the effect of anti-inflammatory treatment with the TNF-α inhibitor infliximab in patients with chronic low back pain and Modic changes. Methods/design The BackToBasic trial is a multicenter, double blind, randomized controlled trial conducted at six hospitals in Norway, comparing intravenous infusions with infliximab with placebo. One hundred twenty-six patients aged 18–65 with chronic low back pain and type 1 Modic changes will be recruited from secondary care outpatients’ clinics. The primary outcome is back pain-specific disability at day 154 (5 months). The study is designed to detect a difference in change of 10 (SD 18) in the Oswestry Disability Index at day 154/ 5 months. The study also aims to refine MRI-assessment, investigate safety and cost-effectiveness and explore the underlying biological mechanisms of Modic changes. Discussion Finding treatments that target underlying mechanisms could pose new treatment options for patients with low back pain. Suppression of inflammation could be a treatment strategy for patients with low back pain and Modic changes. This paper presents the design of the BackToBasic study, where we will assess the effect of an anti-inflammatory treatment versus placebo in patients with chronic low back pain and type 1 Modic changes. The study is registered at ClinicalTrials.gov under the identifier NCT03704363. The EudraCT Number: 2017–004861-29.

Reverse transformation of Modic Type 2 changes to Modic Type 1 changes during sustained chronic low-back pain severity

2007 ◽  
Vol 6 (2) ◽  
pp. 152-155 ◽  
Author(s):  
Laurence A. G. Marshman ◽  
Matthew Trewhella ◽  
Tai Friesem ◽  
Chandra K. Bhatia ◽  
Manoj Krishna
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Chronic Low Back Pain ◽  
Reverse Transformation ◽  
Pain Severity ◽  
Low Back ◽  
Modic Type ◽  
Generating Capacity

✓Modic Type 2 (MT2) neuroimaging changes are considered stable or invariant over time and relatively quiescent, whereas Modic Type 1 (MT1) changes are considered unstable and more symptomatic. The authors report two cases in which MT2 changes were symptomatic and evidently unstable, and in which chronic low-back pain severity remained unaltered despite a MT2–MT1 reverse transformation. Two women (41 and 48 years old) both presented with chronic low-back pain. Magnetic resonance (MR) images demonstrated degenerating discs at L5–S1 associated with well-established MT2 changes in adjacent vertebrae. Repeated MR imaging in these two patients after 11 months and 7 years, respectively, revealed reverse transformation of the MT2 changes into more florid MT1 changes, despite unaltered chronic low-back pain severity. Following anterior discectomy and disc arthroplasty, immediate abolition of chronic low-back pain was achieved in both patients and sustained at 3-year follow up. Modic Type 2 changes are therefore neither as stable nor as quiescent as originally believed. Each type can change, with equal symptom-generating capacity. More representative imaging–pathological correlates are required to determine the precise nature of MT changes.

Poster 285 Systemic Infection Presenting as Acute on Chronic Low Back Pain. Making the Diagnosis: A Case Report

PM&R ◽  
2014 ◽  
Vol 6 (9) ◽  
pp. S284-S285
Author(s):  
Nicole Burns ◽  
Doctor of Osteopathic Medicine ◽  
Jonathan Pedrick
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Case Report ◽  
Chronic Low Back Pain ◽  
Systemic Infection ◽  
Low Back

scholarly journals SPECT/CT imaging of the lumbar spine in chronic low back pain: a case report

2011 ◽  
Vol 19 (1) ◽  
Author(s):  
Michael H Carstensen ◽  
Mashael Al-Harbi ◽  
Jean-Luc Urbain ◽  
Tarik-Zine Belhocine
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Case Report ◽  
Lumbar Spine ◽  
Chronic Low Back Pain ◽  
Ct Imaging ◽  
Low Back

scholarly journals Atraumatic Bilateral Lumbar Pedicle Fractures in a Patient with Back Pain and History of Long- Term Bisphosphonate Therapy: A Case Report

2020 ◽  
pp. 97-102
Author(s):  
Alec L. Meleger
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Case Report ◽  
Lumbar Spine ◽  
Conservative Management ◽  
Chronic Low Back Pain ◽  
Bisphosphonate Therapy ◽  
Low Back ◽  
History Of ◽  
Lumbar Pedicle

of atypical femoral fractures is a known complication of chronic bisphosphonate therapy; however, the finding of atraumatic lumbar pedicle fractures without a prior history of spinal surgery or contralateral spondylolysis is rare. While a few cases of osteoporotic pedicle fractures associated with adjacent vertebral compression fractures have been reported, only a single case of isolated atraumatic bilateral pedicle fractures has been published in a patient who had been on chronic risedronate therapy of 10-year duration. Case Report: The present case report illustrates a 63-year-old man who developed isolated atraumatic bilateral lumbar pedicle fractures after 3 years and 5 months on alendronate treatment. The patient’s past medical history had been significant for osteoporosis with a lumbar spine T-score of -2.7. At the time of initial diagnosis, a comprehensive work-up for secondary causes of osteoporosis proved to be negative; this was followed by initiation of bisphosphonate treatment with 70 mg of alendronate once per week. Ten months after starting bisphosphonate therapy, he underwent magnetic resonance imaging (MRI) of the lumbar spine for low back pain that had not responded to conservative management, with imaging not revealing any evidence of pedicle fractures or pedicle stress reaction. He was again seen in the spine clinic, for atraumatic exacerbation of his chronic low back pain with concurrent right lower extremity radiation, 6 months after stopping bisphosphonate therapy. Since the patient failed to respond to conservative management over the ensuing 6 months, a repeat MRI was obtained, which showed new acute/subacute bilateral L5 pedicle fractures. Conclusion: An isolated atraumatic lumbar pedicle fracture may be an additional type of atypical fracture associated with chronic bisphosphonate therapy in an osteoporotic patient. Key words: Chronic low back pain, bisphosphonate, alendronate, pedicle fracture Pain Medicine

scholarly journals Is single-point acupuncture effective in treating acute low back pain? A case report

2021 ◽  
Author(s):  
Sagun Tiwari ◽  
Namrata Sapkota
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Case Report ◽  
Adverse Events ◽  
Chronic Low Back Pain ◽  
Single Point ◽  
Low Back ◽  
Acute Low Back Pain ◽  
Short Time

Acupuncture is often used for acute and chronic low back pain; however, its efficacy is controversial, primarily for acute low back pain (ALBP). Our case study suggests that single acupuncture could relieve ALBP within a short time without any adverse events.

Sign in / Sign up

Export Citation Format

Share Document