Assessment of IL-17 in Oral Lichen Planus and in Pemphigus Vulgaris

2019 ◽  
Vol 65 (1) ◽  
pp. 343-350
Author(s):  
Ibrahim El-Refai ◽  
Amira Maged ◽  
Dina El-Saady
Keyword(s):  
Lichen Planus ◽  
Oral Lichen Planus ◽  
Pemphigus Vulgaris ◽  
Oral Lichen

scholarly journals Desquamative Gingivitis: Protocols, Procedures and Critical Issues

Proceedings ◽  
2019 ◽  
Vol 35 (1) ◽  
pp. 2
Author(s):  
Paola Carcieri
Keyword(s):  
Lichen Planus ◽  
Mucous Membrane ◽  
Plasma Cell ◽  
Oral Lichen Planus ◽  
Pemphigus Vulgaris ◽  
Mucous Membrane Pemphigoid ◽  
Critical Issues ◽  
Oral Lichen

Desquamative gingivitis (DG) isn’t a specific disorder; it simply represents the gingival manifestation associated with some heterogeneous mucocutaneous disorders, such as oral lichen planus (OLP), mucous membrane pemphigoid (MMP), pemphigus vulgaris (PV), plasma cell gingivitis (PCG) and few others. [...]

scholarly journals Lichen planus: Oral manifestations, differential diagnosis and treatment

2020 ◽  
Vol 36 (81) ◽  
pp. 1980-1994
Author(s):  
Marija Bradić-Vasić ◽  
Ana Pejčić ◽  
Milena Kostić ◽  
Ivan Minić ◽  
Radmila Obradović ◽  
...  
Keyword(s):  
Lichen Planus ◽  
Oral Lichen Planus ◽  
Skin Diseases ◽  
Precancerous Lesion ◽  
Pemphigus Vulgaris ◽  
Clinical History ◽  
Diagnosis And Treatment ◽  
Aged Patients ◽  
Mucous Membranes ◽  
Oral Lichen

Introduction: Some of the typical skin diseases, such as Pemphigus vulgaris, Pemphigoid mucosae oris, Erythema exudativum multiforme, Sclerodremia, Dermatitis herpetiformis-Duhring and Lichen planus, can cause swelling and irritation in mucous membranes of the oral cavity. Aim: The aim of the study was to precise diagnosis and treatment of oral Lichen planus manifestations. Methods: Analyzing the literature data and the experience of clinicians, the most common oral lichen planus manifestations were investigated. Results: This disease most commonly occurs in middle-aged patients (30-60 years) and is more common in women than in men. Oral Lichen planus is rarely seen in children. The disease presents in 0.5% to 2% of the population. Clinical history established the relation between oral Lichen planus and oral carcinoma, and therefore this disease should be considered a precancerous lesion. Conclusion: Dermatoses in the mouth are localized most often in the oral mucosa, both at the height of the occlusal line and in the mucous membrane of the retromolar area, but they can also occur in the mucous membranes of the tongue, the floor of the mouth and lips.

Coexistence of oral lichen planus and pemphigus vulgaris

2018 ◽  
Vol 22 (8) ◽  
pp. 2953-2955
Author(s):  
Kamran Balighi ◽  
HamidReza Mahmoudi ◽  
Soheil Tavakolpour ◽  
Maryam Daneshpazhooh
Keyword(s):  
Lichen Planus ◽  
Oral Lichen Planus ◽  
Pemphigus Vulgaris ◽  
Oral Lichen

scholarly journals Profil lesi oral pada penderita penyakit autoimun

2016 ◽  
Vol 2 (3) ◽  
pp. 147
Author(s):  
Indah Suasani Wahyuni ◽  
Tenny Setiana Dewi ◽  
Erna Herawati ◽  
Dewi Zakiawati
Keyword(s):  
Quality Of Life ◽  
Autoimmune Diseases ◽  
Lichen Planus ◽  
Lupus Erythematosus ◽  
Oral Lichen Planus ◽  
Pemphigus Vulgaris ◽  
Clinical Feature ◽  
Oral Lesions ◽  
Oral Lichen

Oral lesion’s profi le in autoimmune disease. Oral lesions are commonly found in patients with autoimmune diseases as manifestations of the disease or a side effect of the treatment. Oral lesions must be handled properly to prevent secondary infection, relieve pain and improve the patient’s quality of life. The aim of this study is to describe oral lesions profile in patients with autoimmune diseases, including clinical characteristics and location of oral lesions as well as the distribution of age and sex of the patient. The methods were retrospective observation by describing the secondary data from patients with autoimmune handled by Oral Medicine Specialist, Faculty of Dentistry, University of Padjadjaran in dr. Hasan Sadikin Hospital Dental Clinic. Patient files from August 2010 untill August 2014 (n = 66) were used, with the most often diagnosis were Systemic Lupus erythematosus (SLE), Oral lichen planus (OLP) and Pemphigus vulgaris (PV). It is revealed that, the age of patients varied between 9 to 68 years old and there was predominance of female patients. Patients diagnosed with SLE were 26 (39.4%), 12 patients with OLP (18.2%) and 28 patients with PV (42.4%). Based on the clinical feature, the most commonly found type of oral lesion was erosion (n=52/78,8%), while the most commonly predilection was in the buccal mucosa (n = 46/69,7%). In conclusion, intra-oral examination should be used as a routine procedure in the comprehensive management of patients with autoimmune diseases. Dentist have a professional role in the diagnosis of oral lesions and provide appropriate therapy in order to improve the quality of life of patients with autoimmune diseases.ABSTRAKLesi oral biasa ditemukan pada penderita penyakit autoimun sebagai manifestasi penyakit atau efek samping pengobatan kortikosteroid jangka panjang. Lesi oral harus ditangani dengan baik untuk mencegah terjadinya infeksi sekunder, mengatasi rasa sakit dan meningkatkan kualitas hidup penderita. Pengumpulan data gambaran profil lesi oral penderita penyakit autoimun, meliputi karakteristik klinis dan lokasi lesi oral serta distribusi usia dan jenis kelamin penderita belum pernah dilakukan. Metode yang digunakan adalah non eksperimen, retrospektif dan deskripsi data sekunder penderita autoimun yang ditangani oleh bagian Ilmu Penyakit Mulut FKG Universitas Padjadjaran di SMF Gigi dan Mulut RS dr. Hasan Sadikin Bandung. Data pasien yang dipergunakan antara bulan Agustus 2010 sampai Agustus 2014 (n=66), dengan diagnosis penyakit autoimun yang paling sering adalah Sistemic Lupus Erythematous (SLE), Oral Lichen Planus  (OLP) dan Pemphigus Vulgaris (PV). Semua pasien memberikan persetujuan pada saat dilakukan pemeriksaan dan  pengumpulan data melalui informed consent. Hasil penelitian ini menunjukkan usia penderita bervariasi antara 9 hingga 68 tahun dan jumlah penderita wanita lebih banyak daripada pria. Penderita yang didiagnosis SLE 26 orang (39,4%), OLP 12 orang (18,2%) dan PV 28 orang (42,4%). Berdasarkan gambaran klinisnya jenis lesi oral yang banyak ditemukan adalah erosi (n = 52/ 78,8%) dan berdasarkan lokasi lesi oral banyak ditemukan pada mukosa bukal (n = 46/69,7% penderita). Kesimpulannya, pemeriksaan intra oral disarankan menjadi prosedur rutin dalam tatalaksana komprehensif penderita penyakit autoimun. Dokter gigi diharapkan dapat berperan dalam mendiagnosis lesi oral dan memberikan terapi yang tepat sehingga dapat meningkatkan kualitas hidup penderita penyakit autoimun. 

Pemphigus vulgaris and pemphigus foliaceus coexisting with oral lichen planus

1980 ◽  
Vol 102 (5) ◽  
pp. 585-590 ◽  
Author(s):  
B. NEUMANN-JENSEN ◽  
N. WORSAAE ◽  
E. DABELSTEEN ◽  
S. ULLMAN
Keyword(s):  
Lichen Planus ◽  
Oral Lichen Planus ◽  
Pemphigus Vulgaris ◽  
Pemphigus Foliaceus ◽  
Oral Lichen

scholarly journals Immune-Mediated Desquamative Gingivitis and Optical Coherence Tomography Diagnostic Patterns: Clinical Implication from a Systematic Review

Diagnostics ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 1453
Author(s):  
Vera Panzarella ◽  
Alessia Bartolone ◽  
Vito Rodolico ◽  
Giorgia Capocasale ◽  
Laura Maniscalco ◽  
...  
Keyword(s):  
Systematic Review ◽  
Optical Coherence Tomography ◽  
Lichen Planus ◽  
Mucous Membrane ◽  
Oral Lichen Planus ◽  
Pemphigus Vulgaris ◽  
Mucous Membrane Pemphigoid ◽  
Optical Coherence ◽  
Immune Mediated ◽  
Oral Lichen

Desquamative Gingivitis (DG) comprises heterogeneous clinical manifestations of numerous immune-mediated muco-cutaneous diseases. Optical Coherence Tomography (OCT) has been proposed as a valuable diagnostic support even if, to date, there are no standardized OCT-diagnostic patterns applicable to DGs. A systematic review was performed to detect existing data on in vivo OCT diagnostic patterns of the most common immune-mediated DGs (i.e., pemphigus vulgaris, mucous membrane pemphigoid and oral lichen planus). It has been found that OCT exhibits specific patterns that address the diagnosis of DG by pemphigus vulgaris (i.e., intraepithelial unilocular blister, reduced epithelial thickness, presence of acantholytic cells in the blister) and by mucous membrane pemphigoid (i.e., subepithelial multilocular blister, presence of inflammatory infiltrate), but not by oral lichen planus. These patterns could offer an attractive diagnostic OCT framework to support the clinical preliminary assessment and monitoring of these complex pathological conditions.

Mucosal disease

2018 ◽  
Author(s):  
Kathy Taghipour
Keyword(s):  
Autoimmune Disease ◽  
Lichen Planus ◽  
Oral Lichen Planus ◽  
Pemphigus Vulgaris ◽  
Stevens Johnson Syndrome ◽  
Mucosal Disease ◽  
Johnson Syndrome ◽  
Dermatological Condition ◽  
A Cell ◽  
Oral Lichen

This chapter discusses the following mucous membrane disorders: pemphigus vulgaris, lichen planus, and Stevens–Johnson syndrome. Pemphigus vulgaris is an autoimmune disease that affects the skin and the mucosal membranes with blisters and erosions. Lichen planus is a cell-mediated immunological mucocutaneous disease; oral lichen planus may present with erosions, white streaks, or plaques in the oral cavity. Stevens–Johnson syndrome is an emergency dermatological condition in which an immunological hypersensitivity causes erosions and inflammation of mucosal membranes and the skin. As well as providing definitions of these diseases, this chapter discusses their etiology, typical symptoms, uncommon symptoms, demographics, natural history, complications, diagnostic approach, other diagnoses that should be considered, prognosis, and treatment.

scholarly journals Dental Implant Rehabilitation in Patients Suffering from Mucocutaneous Diseases: A Systematic Review and Meta-Analysis

2018 ◽  
Vol 12 (1) ◽  
pp. 873-883 ◽  
Author(s):  
Parichehr Zarean ◽  
Paridokht Zarean ◽  
Negar Kanounisabet ◽  
Ahmad Moghareabed ◽  
Mansour Rismanchian ◽  
...  
Keyword(s):  
Risk Factors ◽  
Systematic Review ◽  
Systemic Lupus Erythematosus ◽  
Lichen Planus ◽  
Lupus Erythematosus ◽  
Oral Lichen Planus ◽  
Meta Analysis ◽  
Pemphigus Vulgaris ◽  
Systemic Lupus ◽  
Oral Lichen

Objective: Dental implantations are widely used for oral rehabilitation of edentulous patients. Despite high success rate, there are some risk factors that have been associated with failures. Oral mucocutaneous diseases are one of these risk factors for implant insertion due to the immunosuppressive therapy. There are limited studies that have dealt with the subject of dental implantology in oral mucosal disorders mainly with patients with oral lichenplanus, pemphigoid, pemphigus vulgaris, and systemic lupus erythematosus. In order to assess the result of implantations in such patients, we have reviewed the studies. Materials and Methods: We searched PubMed, Science Direct, and Cochrane databases for articles published from Jan 2000 to Dec 2017, using key search word “dental implants”, “oral lichen planus”, “pemphigoid”, “pemphigus vulgaris” and ”systemic lupus erythematosus”. Results: The random effects analysis result shows overall failure rates of 22% in patients with oral lichen planus. A systematic review revealed some failures that are not definitely related to these diseases. Conclusion: Due to the lack of adequate studies, a meta-analysis was only possible for oral lichen planus. Presently, there is no definite guideline regarding the placement of implant in patients suffering from mucocutaneous diseases; nevertheless, we should always consider that these patients are specific cases and need more attention in the first step of treatment and follow-ups. So there is a need to further clinical studies in order to evaluate more risk factors accurately and make a definitive conclusion.

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