scholarly journals Surfactant Lung Lavage versus Standard Treatment for Meconium Aspiration Syndrome

2021 ◽  
Vol 89 (9) ◽  
pp. 2075-2082
Author(s):  
TAREK K. ALSAYAD, M.D.; EHAB I. SOROUR, M.D. ◽  
MOHAMED MOUSTAFA, M.D.; ASHRAF ABDELKADER, M.D.
2008 ◽  
Vol 71 (2) ◽  
pp. 103-109 ◽  
Author(s):  
Chiao-Wei Lo ◽  
Mei-Jy Jeng ◽  
Feng-Yu Chang ◽  
Ja-Fang Yang ◽  
Yu-Sheng Lee ◽  
...  

2007 ◽  
Vol 43 (7-8) ◽  
pp. 539-545 ◽  
Author(s):  
Peter A Dargaville ◽  
John F Mills ◽  
Beverley Copnell ◽  
Peter M Loughnan ◽  
Peter N McDougall ◽  
...  

2012 ◽  
Vol 102 (2) ◽  
pp. e90-e93 ◽  
Author(s):  
Peter A Dargaville ◽  
Beverley Copnell ◽  
John F Mills ◽  
Ismail Haron ◽  
Jimmy KF Lee ◽  
...  

2020 ◽  
Vol 9 (8) ◽  
pp. 527-536
Author(s):  
Mohammed Ahmed Abdelaal ◽  
Dina Abushanab ◽  
Daoud Al-Badriyeh

Aim: To conduct a systematic overview of systematic reviews (SRs) and randomized clinical trials (RCTs) on surfactant therapy in neonatal meconium aspiration syndrome. Methods: We searched EMBASE, PROQUEST and PubMed to summarize the different effects of surfactant lung lavage and bolus surfactant therapies in neonates with meconium aspiration syndrome. Results: With a total of 1377 patients, three SRs and two RCTs were included in analysis. Surfactant effectiveness was concluded by low-quality SRs, with high risk of bias, which was contradicted by high-quality SRs, with low risk of bias. In SRs, the surfactant lung lavage reduced mortality, need for extracorporeal membrane oxygenation and hospitalization, while the bolus surfactant did not. In recent high-quality RCTs, however, the two modalities did not significantly differ. Conclusion: The evidence on surfactant effectiveness and its method of administration is sparse and inconsistent.


Neonatology ◽  
2008 ◽  
Vol 94 (3) ◽  
pp. 160-163 ◽  
Author(s):  
Peter A. Dargaville ◽  
Beverley Copnell ◽  
David G. Tingay ◽  
Michael J. Gordon ◽  
John F. Mills ◽  
...  

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