scholarly journals Relationship between Arterial and Venous Blood Gases in Patients Presenting with Chronic Obstructive Pulmonary Disease

2018 ◽  
Vol 24 (1) ◽  
pp. 684-688
Author(s):  
Muhammad Nusrullah ◽  
Muhammad Younus ◽  
Yasir Nasir

Arterial blood gas analysis is an important test for determining acid base balance of the body. Chronic obstructive pulmonary disease is characterized by chronic airflow limitation which is not fully reversible and it can lead to respiratory failure. Objective: To determine the correlation between arterial and venous blood gases in patients presenting with chronic obstructive pulmonary disease. Material and Methods: This cross sectional study was conducted at Department of Chest Medicine, Mayo Hospital, Lahore, Pakistan. After meeting the inclusion criteria, 100 patients were enrolled. Informed consent was taken and demographic information was obtained. Blood sample was obtained anaerobically from the radial artery and from a dorsal hand vein using 2 separate 5cc BD heparinized syringes with needle size 22G for each patientand pH, PCO2, and HCO3 were analyzed. All the collected data was entered and analyzed on SPSS version 21.Results: The mean age of the patients was 52.68±10.51 years. Strong relationship was found between the VBGs and ABGs in pH, PCO2 and HCO3 i.e. r=0.913, 0.999 and 0.994 (p-value <0.0001), respectively. Conclusion: A strong correlation was found among ABG’s and VBGs in patients presenting with COPD.

2014 ◽  
Vol 2014 ◽  
pp. 1-12 ◽  
Author(s):  
Shaonan Liu ◽  
Johannah Shergis ◽  
Xiankun Chen ◽  
Xuhua Yu ◽  
Xinfeng Guo ◽  
...  

Objective. To evaluate the efficacy and safety ofWeijingdecoction combined with routine pharmacotherapy (RP) for the treatment of acute exacerbations of chronic obstructive pulmonary disease (AECOPD).Methods. Randomized controlled trials (RCT) evaluatingWeijingdecoction for AECOPD were included. English, Chinese, and Japanese databases were searched from their respective inceptions to June 2013. The methodological quality was assessed according to the Cochrane Collaboration’s risk of bias tool. All data were analyzed and synthesized using RevMan 5.2 software.Results. Fifteen (15) studies involving 986 participants were included. Participants were diagnosed with COPD in the acute exacerbation stage. In addition, most of studies reported that they included participants with the Chinese medicine syndrome, phlegm-heat obstructing the Lung.Weijingdecoction combined with RP improved lung function (forced expiratory volume in one second; FEV1), arterial blood gases (PaO2 and PaCO2), clinical effective rate, and reduced inflammatory biomarkers (TNF-αand IL-8) when compared with RP alone. No severe adverse events were reported in these studies.Conclusions.Weijingdecoction appeared to be beneficial for AECOPD and well-tolerated when taken concurrently with RP, such as antibiotics, bronchodilators (oral and inhaled), and mucolytics.


Sign in / Sign up

Export Citation Format

Share Document