A next-generation smallpox vaccine candidate, Imvamune,* has demonstrated promising results

2007 ◽  
Vol &NA; (1617) ◽  
pp. 8
Author(s):  
&NA;
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Charles E. McGee ◽  
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David J. Pickup ◽  
...  

Modified vaccinia Ankara virus (MVA) is a smallpox vaccine candidate. This study was performed to determine if MVA vaccination provides long-term protection against rabbitpox virus (RPXV) challenge, an animal model of smallpox. Two doses of MVA provided 100% protection against a lethal intranasal RPXV challenge administered 9 months after vaccination.


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