scholarly journals Assessment of immunohematological, hematological and biochemical responses in cultivable fish Cyprinus carpio exposed to an antibiotic sulfamethoxazole (SMX)

2020 ◽  
Author(s):  
Nazish Iftikhar ◽  
Imran Hashmi
Keyword(s):  
Cyprinus Carpio ◽  
Prolonged Exposure ◽  
Dose Response Relationship ◽  
Respiratory Burst Activity ◽  
Blood Profile ◽  
Common Carp Cyprinus Carpio ◽  
Toxicity Potential ◽  
Nitroblue Tetrazolium Reduction ◽  
Biochemical Indices ◽  
Tetrazolium Reduction

Abstract Sulfamethoxazole (SMX) is a member of the sulfonamides group of antibiotics which is used extensively in aquaculture throughout the world. In this study, common carp (Cyprinus carpio) was used as the bioindicator to assess the toxicity potential of SMX. Effects were based on chronic toxicity of environmentally relevant dosages of 25, 50, 100, and 200 μg/L of SMX for 28 days. Cytotoxicity through hematology and biochemistry showed a dose–response relationship. Numerous variations were recorded in blood profile and biochemical parameters in SMX-exposed groups when compared to control. Hemoglobin, platelet, and erythrocyte levels were significantly decreased. Leukocyte level was significantly increased with values ranging from 131 to 303 (×103/μL). Changes in biochemical indices: glucose, total protein, and triglycerides showed biphasic trend, but alanine transaminase secretion was significantly increased from 25.13 to 204 U/L at higher concentration compared to control, suggesting liver damage. Spectrophotometric nitroblue tetrazolium reduction assay showed that respiratory burst activity increased as a function of SMX dose and exposure time (0.48–1.33 absorbance) ultimately leading to reduction in immunity. The present study highlights that prolonged exposure of SMX affects biochemistry, hematology, and immunohematology of fish and these biomarkers act as an effective tool for environmental risk assessment of drugs in the aquatic environment.

The effect of praziquantel applied per os on selected haematological and biochemical indices in common carp (Cyprinus carpio L.)

2008 ◽  
Vol 35 (4) ◽  
pp. 599-605 ◽  
Author(s):  
Eliška Sudová ◽  
Veronika Piačková ◽  
Hana Kroupová ◽  
Martin Pijáček ◽  
Zdeňka Svobodová
Keyword(s):  
Common Carp ◽  
Cyprinus Carpio ◽  
Common Carp Cyprinus Carpio ◽  
Carp Cyprinus Carpio ◽  
Biochemical Indices

scholarly journals Concentration related differences in the inhibition of acetylcholinesterase activity in the common carp Cyprinus carpio by Phorate, an organophosphorous insecticide

2016 ◽  
Vol 2 (4) ◽  
pp. 83
Author(s):  
G Lakshmaiah
Keyword(s):  
Common Carp ◽  
Cyprinus Carpio ◽  
Ache Activity ◽  
Prolonged Exposure ◽  
Exposure Period ◽  
Acetylcholinesterase Activity ◽  
Dependent Manner ◽  
Concentration Dependent Manner ◽  
Common Carp Cyprinus Carpio ◽  
Carp Cyprinus Carpio

The activity of acetylcholinesterase (AChE) in the vital organs of fish such as gill, liver, muscle, kidney and brain of the freshwater common carp Cyprinus carpio (C. carpio) was investigated after exposing to acute lethal toxicity (ALT) and chronic sublethal toxicity (CST) of phorate. C. carpio fish were exposed to ALT (LC50/96 hours - 0.71 ppm/l) of Phorate for one day and 4 days and CST (one-tenth of the LC50/96 hours - 0.071 ppm/l) of Phorate for 1, 7, 15 and 30 days and the concentration related differences in the inhibition and recovery of the AChE enzyme activity was evaluated in the target organs of the fish. Relative to controls, the activity of AChE in all the organs of the fish exposed to ATP gradually decreased significantly ((P<0.05)) at 1 and 4 days of exposure period whereas in the fish exposed to CTP the AChE activity was elevated at day 1 and gradually decreased from day 7 to day 15 followed by an increase at day 30 in all the organs significantly (P<0.05). Based on the percent values obtained the inhibition of AChE activity was predominantly more in the organs of the fish exposed to ATP in a concentration-dependent manner. On prolonged exposure for 30 days in CTP the AChE activity was restored gradually depending on the initial pesticide exposure concentration. Findings from this study have demonstrated that inhibition of AChE activity in C. carpio is a useful biomarker for assessment of anticholinesterase pesticide contaminations in water.

scholarly journals Effects of replacing fish meal with sunflower meal on growth performance, body composition, hematological and biochemical indices of common carp (Cyprinus carpio) fingerlings

2018 ◽  
Vol 26 (2) ◽  
pp. 121-129
Author(s):  
Kamyar Javid Rahmdel ◽  
Hamid Allaf Noveirian ◽  
Bahram Falahatkar ◽  
Aria Babakhani Lashkan
Keyword(s):  
Body Composition ◽  
Common Carp ◽  
Cyprinus Carpio ◽  
Fish Meal ◽  
Average Weight ◽  
Sunflower Meal ◽  
Hematological Indices ◽  
Common Carp Cyprinus Carpio ◽  
Negative Impacts ◽  
Biochemical Indices

Abstract The aim of the present study was to evaluate the effects of replacing fish meal with sunflower meal had on common carp, Cyprinus carpio L. fingerlings. A total of 455 fish with an average weight of 3.03 ± 0.36 g were distributed in 15 fiberglass tanks and fed five isonitrogenous and isoenergetic diets with replacement levels of 0 (control), 25, 50, 75, and 100% of fish meal with sunflower meal for 10 weeks. Based on the results, the highest and lowest final weights were observed at 25 and 100%, respectively, although the differences at 50 and 75% were not significant compared to the control. Significant differences were observed in body composition excluding ash content. Differences in all hematological indices among treatments were not significant, but in plasma biochemical indices, there was a significant decline in triglyceride levels at 100%, and cholesterol was significantly higher in the control. The results of the current study demonstrate that replacing fish meal with sunflower meal is possible up to 75% for common carp fingerlings without negative impacts on growth, body composition, or hematological and plasma biochemical indices.

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