Iron Forms That Influence the Growth and Musty Odor Production of Selected Cyanobacteria

1992 ◽  
Vol 25 (2) ◽  
pp. 207-216 ◽  
Author(s):  
S. Nakashima ◽  
M. Yagi

In order to clarify the mechanism of growth of musty-odor producing cyanobacteria, the effects of iron forms on growth and musty-odor production in four species of cyanobacteria, Oscillatoriabrevis, Anabaenamacrospora, Phormidiumtenue and Oscillatoriatenuis were studied using laboratory batch cultures. The former two cyanobacteria produce geosmin and the latter two produce 2-methylisoborneol (MIB). The growth of A. macrospora, P. tenue and O. tenuis was suppressed in the EDTA (chelating agent)-free CT medium. However, O. brevis grew well and produced geosmin in this medium as well as in the presence of EDTA. Thus, O. brevis showed an ability to utilize colloidal iron and even iron oxides for its growth. This suggests that O. brevis would be expected to produce a specific high affinity iron chelator (siderophore) in the chelator-free medium. In the presence of bathophenanthroline disulfonate (BPDS), a strong Fe(II) chelating agent, O. brevis and P. tenue were able to grow, but A. macrospora and O.tenuis did not. Furthermore, O.brevis was capable of growing in the medium containing a microbial siderophore, desferrioxamine B(DESF), instead of EDTA, but the other three cyanobacteria did not grow. These results show that O. brevis has an excellent ability to utilize a variety of iron forms including Fe (II I)-EDTA, Fe (II)-BPDS,.Fe (III)-DESF chelates, colloidal ferric hydroxide and more thermodynamically stable crystalline iron oxides (Fe2O3 and Fe3O4) in comparison with the other three musty-odor producing cyanobacteria isolated from Lake Biwa.

Clay Minerals ◽  
1998 ◽  
Vol 33 (3) ◽  
pp. 453-465 ◽  
Author(s):  
I. Gonzalez ◽  
E. Galan ◽  
A. Miras ◽  
P. Aparicio

AbstractAn attempt has been made to assess new potential applications for the Bailén clays, traditionally used for manufacturing bricks, based on mineralogical, chemical, particle size, plasticity and firing results. Raw materials and mixtures used by the local factory were selected and tested with the addition of some diatomite, feldspar or kaolin. Based on their properties, clay materials from Bailén might be suitable for making porous red wall tiles, clinker, vitrified red floor tiles and porous light-coloured wall tiles by pressing; the first could be manufactured from the raw materials and mixtures currently used by the local manufactures. On the other hand, stoneware shaped by extrusion, such as perforated bricks, facing bricks and roofing tiles, can be also manufactured from the mixtures used at the factory if they contain 20-25% carbonate and small amounts of iron oxides; lightweight bricks require black and yellow clays with diatomite.


1986 ◽  
Vol 112 (2) ◽  
pp. 412-420 ◽  
Author(s):  
T.David Waite ◽  
Alex Torikov ◽  
J.David Smith
Keyword(s):  

1967 ◽  
Vol 2 (4) ◽  
pp. 499-512
Author(s):  
E. L. BENEDETTI ◽  
P. EMMELOT

Plasma membranes were isolated from rat liver and a transplanted rat hepatoma of the hepatocellular type. After glutaraldehyde fixation the membranes were treated with colloidal iron hydroxide (CIH) at pH 1.7, which was found to react specifically with the neuraminidase-sensitive sialic acid of the liver membranes. The CIH-reactive, neuraminidase-sensitive sialic acid, comprising 70% of the membrane-bound sialic acid, was exclusively located in the outer leaflet of the liver membranes as shown by the rather regular distribution of electron-dense CIH granules. This granular, asymmetric type of staining was also observed in the hepatoma membranes, which contained some 50% more sialic acid than did the liver membranes. In addition, the hepatoma membranes showed an intense and uniform staining by CIH of short segments of both membrane leaflets; the latter type of staining was but little impaired by neuraminidase pre-treatment. None of the junctional complexes of the liver membranes was stained by CIH. Tight junctions were very rarely observed in the hepatoma membrane preparations, and the desmosomes and intermediate junctions of these membranes not infrequently exhibited a loosened appearance exposing CIH-reactive neuraminidase-sensitive sialic acid at their opposite plates. This aspect could be induced in the desmosomes and intermediate junctions, but not in the tight junctions, by pre-treatment of the liver membranes with the chelating agent ethylenediaminetetra-acetate.


Blood ◽  
2016 ◽  
Vol 128 (22) ◽  
pp. 3620-3620
Author(s):  
Sule Unal ◽  
Neslihan Kalkan ◽  
Mualla Cetin ◽  
Fatma Gumruk

Abstract Introduction: Iron overload is one of themajor complicationsof transfusion treatment in patient with thalassemia major. Deferasirox is a once-daily orally active iron chelator and long-term efficacy and safety data are being published. Herein we report the long-term follow-up data of thalassemia major patients in a single center. Methods: Of the 67 patients with thalassemia major who were under follow-up in a single center, 42 who were on deferasirox chelation for at least three years were included in the study. Patients' initial serum ferritin, ALT, creatinine, cardiac T2* and hepatic T2* values were recorded at the time of deferasirox initiation and at last visit. Deferasirox was not initiated as an iron chelator to none of the patients with a cardiac T2* value below 8 ms. All of the patients had creatinine clearance above 40 ml/minute and had serum creatinine levels within age appropriate normals at deferasirox initiation. None of the patients received any other chelations during the follow-up period. Results: Mean age of the patients were 16±9.4 years (2-33.4 years) at initiation of deferasirox and 22 (52%) were females. Eighteen (43%) of the patients were splenectomized. Median follow-up time of deferasirox chelation was 7.9 years (3-10). The median deferasirox doses at initiation of chelation and at last visit were 20.5 mg/kg/day and 30.7 mg/kg/day (7-40), respectively. Serum ferritin levels decreased significantly with deferasirox chelation (median 1969 ng/ml (516-5404) vs 1113 ng/ml (339-4003), p<0,001). We did not find statistically significant difference between the inital cardiac T2* values and the values at the last visit (median 25 .3 ms((8.7-42) vs 32 ms (6.6-42), p=0.607), despite a dramatic increase. On the other hand, hepatic T2* values did not significantly change compared to initial values, as well (median 3.7 ms (1-13.6) vs 3.3 (1-16), p=0.865). However of the patients who had cardiac T2* value between 10-20 ms, 67% was found to have T2* value above 20 ms by the end of the follow-up duration. On the other hand 53% of the patients with hepatic T2* value below 3.5 ms, had T2* values above 3.5 ms by the end of the follow-up, indicating improvement in iron stores. None of the patients exibited an adverse event that requires cessation of the drug totally, but patients exibited transient hypertransaminasemia that required transient cessation and/or dose decrement. The changes in serum ALT and serum creatinine levels at the initiation and at last visit were not significant. Conclusions: This is a a study that includes patients with a relatively long duration of follow-up. Although the cardiac T2* values improved by the end of the follow-up, this change was not found statistically significant. This can be attributed to the sample size and in a larger sample size, the change might be found significant. Additionally, the patients included in the study were composed of not only naive patients to chelation but also of the patients who were imcomplant to previous chelation and who were highly iron loaded before initiation of deferasirox. Disclosures No relevant conflicts of interest to declare.


Langmuir ◽  
1990 ◽  
Vol 6 (3) ◽  
pp. 555-559 ◽  
Author(s):  
P. Mulvaney ◽  
V. Swayambunathan ◽  
F. Grieser ◽  
D. Meisel

1978 ◽  
Vol 58 (4) ◽  
pp. 475-486 ◽  
Author(s):  
J. C. MUNCH ◽  
Th. HILLEBRAND ◽  
J. C. G. OTTOW

In model experiments under controlled conditions of pH, particle size and amount of glucose, changes in the free Fe oxides (Fed) and acid oxalate soluble Fe (Feo) of six soils were studied after inoculation with iron-reducing, nitrogen-fixing Clostridia. In all soils, the total amount of Fed as well as crystalline Fe (Fed-Feo) decreased immediately and significantly, while Fe(II) in solution increased sigmoidally and was inversely proportional to changes in pH. Feo remained relatively constant throughout the incubation period. As a consequence, the Feo/Fed ratio increased in all samples. At the end of the reduction process, total dissolved Fe(II) correlated with the original Feo content and showed a negative correlation to Fed-Feo. These results are explained by a mechanism in which active non-crystalline iron oxides are reduced in preference to the crystalline forms. The latter are probably transformed and reduced to non-crystalline forms but not until all available active non-crystalline oxides have been exhausted. In the discussion, the reliability of acid oxalate-soluble Fe as a measure of the non-crystalline, active pedogenic iron forms is outlined. Further, the significance of a lowered redox potential (Eh or rH) in reductive transformations of flooded soils is analyzed.


1991 ◽  
Vol 40 (1-3) ◽  
pp. 133-142 ◽  
Author(s):  
Jacinta Enzweiler ◽  
Inés Joekes

1987 ◽  
Vol 8 (1-12) ◽  
pp. 95-103 ◽  
Author(s):  
Norio Sugiura ◽  
Osami Yagi ◽  
Ryuichi Sudo
Keyword(s):  

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