Adrenal Hyperandrogenism and Polycystic Ovary Syndrome

2016 ◽  
Vol 22 (36) ◽  
pp. 5588-5602 ◽  
Author(s):  
Manuel Luque-Ramírez ◽  
Héctor Escobar-Morreale
Keyword(s):  
Polycystic Ovary Syndrome ◽  
Polycystic Ovary ◽  
Ovary Syndrome ◽  
Adrenal Hyperandrogenism

Influence of adrenal hyperandrogenism on the clinical and metabolic phenotype of women with polycystic ovary syndrome

2015 ◽  
Vol 103 (3) ◽  
pp. 795-801.e2 ◽  
Author(s):  
Macarena Alpañés ◽  
Manuel Luque-Ramírez ◽  
M. Ángeles Martínez-García ◽  
Elena Fernández-Durán ◽  
Francisco Álvarez-Blasco ◽  
...  
Keyword(s):  
Polycystic Ovary Syndrome ◽  
Polycystic Ovary ◽  
Metabolic Phenotype ◽  
Ovary Syndrome ◽  
Adrenal Hyperandrogenism

Genetic susceptibility for adrenal hyperandrogenism in polycystic ovary syndrome

2017 ◽  
Author(s):  
Nicoleta Baculescu ◽  
Sarah Haydar ◽  
Monica Livia Gheorghiu ◽  
Serban Radian ◽  
Corinne Lautier ◽  
...  
Keyword(s):  
Polycystic Ovary Syndrome ◽  
Genetic Susceptibility ◽  
Polycystic Ovary ◽  
Ovary Syndrome ◽  
Adrenal Hyperandrogenism

scholarly journals Increased clearance of cortisol by 5β-reductase in a subgroup of women with adrenal hyperandrogenism in polycystic ovary syndrome

2009 ◽  
Vol 32 (3) ◽  
pp. 210-218 ◽  
Author(s):  
A. Gambineri ◽  
G. Forlani ◽  
A. Munarini ◽  
F. Tomassoni ◽  
G. E. Cognigni ◽  
...  
Keyword(s):  
Polycystic Ovary Syndrome ◽  
Polycystic Ovary ◽  
Ovary Syndrome ◽  
Adrenal Hyperandrogenism

scholarly journals Adrenocortical Production Is Associated with Higher Levels of Luteinizing Hormone in Nonobese Women with Polycystic Ovary Syndrome

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Luciana Tock ◽  
Gláucia Carneiro ◽  
Andrea Z. Pereira ◽  
Sérgio Tufik ◽  
Maria Teresa Zanella
Keyword(s):  
Insulin Resistance ◽  
Luteinizing Hormone ◽  
Polycystic Ovary Syndrome ◽  
Salivary Cortisol ◽  
Polycystic Ovary ◽  
Dehydroepiandrosterone Sulfate ◽  
Common Finding ◽  
Ovary Syndrome ◽  
Adrenal Hyperandrogenism ◽  
And Control

Objective.Insulin resistance (IR) and ovarian and adrenal hyperandrogenism are a common finding in women with polycystic ovary syndrome (PCOS). The aim of the present study was to access possible differences in insulin resistance, gonadotropins, and androgens production in obese and nonobese PCOS women.Study Design.We studied 37 PCOS women (16 nonobese and 21 obese) and 18 nonobese controls. Fasting glucose, insulin, androgens, and gonadotropins levels were determined. Salivary cortisol was measured basal and in the morning after dexamethasone (DEX) 0.25 mg.Results.Nonobese PCOS women showed higher basal salivary cortisol and serum dehydroepiandrosterone sulfate and luteinizing hormone (LH) levels than controls and obese PCOS. These hormones levels did not differ between the obese and control groups. After DEX administration no differences were found between the three groups. In PCOS women, salivary cortisol levels showed negative correlation with BMI (r=-0.52;P=0.001) and insulin (r=-0.47;P=0.003) and positive correlation with LH (r=0.40;P=0.016).Conclusion.Our results show an increased adrenocortical production in nonobese PCOS women, not related to IR and associated with a normal hypothalamic-pituitary-adrenal suppression. Higher LH levels might be involved in this event.

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