A Literature Review of Enzyme Kinetic Parameters for CYP3A4-Mediated Metabolic Reactions of 113 Drugs in Human Liver Microsomes: Structure- Kinetics Relationship Assessment

2006 ◽  
Vol 7 (3) ◽  
pp. 231-249 ◽  
Author(s):  
H.- Bu
Keyword(s):  
Literature Review ◽  
Kinetic Parameters ◽  
Human Liver ◽  
Liver Microsomes ◽  
Human Liver Microsomes ◽  
Enzyme Kinetic ◽  
Metabolic Reactions ◽  
Relationship Assessment

In vitro inhibitory effects of Kampo medicines on metabolic reactions catalyzed by human liver microsomes

2003 ◽  
Vol 28 (4) ◽  
pp. 319-327 ◽  
Author(s):  
K. Takahashi ◽  
E. Uejima ◽  
T. Morisaki ◽  
K. Takahashi ◽  
N. Kurokawa ◽  
...  
Keyword(s):  
Human Liver ◽  
Liver Microsomes ◽  
Human Liver Microsomes ◽  
Inhibitory Effects ◽  
Metabolic Reactions

Molecular docking and enzyme kinetic studies of dihydrotanshinone on metabolism of a model CYP2D6 probe substrate in human liver microsomes

Phytomedicine ◽  
2012 ◽  
Vol 19 (7) ◽  
pp. 648-657 ◽  
Author(s):  
Xuelin Zhou ◽  
Yan Wang ◽  
Penelope M.Y. Or ◽  
David C.C. Wan ◽  
Yiu Wa Kwan ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Human Liver ◽  
Liver Microsomes ◽  
Kinetic Studies ◽  
Human Liver Microsomes ◽  
Enzyme Kinetic

Enzyme kinetic study of a new cardioprotective agent, KR-32570 using human liver microsomes and recombinant CYP isoforms

2007 ◽  
Vol 30 (4) ◽  
pp. 469-474 ◽  
Author(s):  
Hyojin Kim ◽  
Kyung-Ah Seo ◽  
Hyunmi Kim ◽  
Hye Suk Lee ◽  
Choong-Hwan Lee ◽  
...  
Keyword(s):  
Kinetic Study ◽  
Human Liver ◽  
Liver Microsomes ◽  
Human Liver Microsomes ◽  
Enzyme Kinetic ◽  
Cyp Isoforms ◽  
Enzyme Kinetic Study

Deactivation of anti-cancer drug letrozole to a carbinol metabolite by polymorphic cytochrome P450 2A6 in human liver microsomes

Xenobiotica ◽  
2009 ◽  
Vol 00 (00) ◽  
pp. 090901052053001-8
Author(s):  
K. Murai ◽  
H. Yamazaki ◽  
K. Nakagawa ◽  
R. Kawai ◽  
T. Kamataki
Keyword(s):  
Cytochrome P450 ◽  
Human Liver ◽  
Liver Microsomes ◽  
Human Liver Microsomes ◽  
Cancer Drug ◽  
Anti Cancer ◽  
Cytochrome P450 2A6

Selegiline Metabolism and Cytochrome P450 Enzymes:In vitro Study in Human Liver Microsomes*

2000 ◽  
Vol 86 (5) ◽  
pp. 215-221 ◽  
Author(s):  
Paivi Taavitsainen ◽  
Markku Anttila ◽  
Leena Nyman ◽  
Hari Karnani ◽  
Jarmo S. Salonen ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Human Liver ◽  
Liver Microsomes ◽  
Human Liver Microsomes ◽  
Vitro Study
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