Current MRI Methods for the Assessment of Pathologic Prostate: A Brief Review for Clinician

2021 ◽  
Vol 18 ◽  
Author(s):  
Shirley-Yoselin Salazar-Ruiz ◽  
Maria-Fatima Chilaca-Rosas ◽  
Irma-Gabriela Sanchez-Rodriguez ◽  
Roberto Corona-Cedillo ◽  
Sergey K. Ternovoy ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Prostate Gland ◽  
Predictive Biomarkers ◽  
Clinical Anatomy ◽  
Normal Prostate ◽  
Cancer Management ◽  
Magnetic Resonance Imaging Mri ◽  
Prostate Cancer Management ◽  
Lower Urinary

: The application of magnetic resonance imaging (MRI) have helped in different modalities for prostate cancer management, from early detection to treatment planning and follow-up, the evolution of MRI techniques allows to obtain not only anatomical but also functional information to take advantage of prostate cancer detection and staging while supplying prognostic and predictive biomarkers. This review presents conventional and advanced MRI techniques (known as multiparametric MRI) that allow functional and quantitative assessment of the normal prostate gland and its correlation with prostate cancer. Additional topics include the epidemiology of prostate cancer following the Global Burden Diseases Cancer Collaboration 2018, the clinical anatomy of the prostate gland, and the lower urinary tract; we also mention some aspects of the diagnosis performance in ultrasound. We end the review with a brief explanation about the anatomical foundation of external-beam planning radiotherapy.

scholarly journals Prostate cancer management challenges due to COVID-19 in countries with low-to-middle-income economies: A radiation oncology perspective

2020 ◽  
Vol 80 (4) ◽  
pp. 1-14
Author(s):  
María Caicedo-Martínez ◽  
Alejandro González-Motta ◽  
Sebastián R. Gil-Quiñones ◽  
Juan Carlos Galvis
Keyword(s):  
Prostate Cancer ◽  
Radiation Oncology ◽  
Healthcare Personnel ◽  
Urologic Oncology ◽  
Middle Income ◽  
Image Guided Radiation Therapy ◽  
Cancer Management ◽  
Prostate Cancer Management ◽  
Oncology Center

Description: The COVID-19 pandemic poses an unprecedented challenge for urologic oncology and radiotherapy. Radiation oncology departments and international collaboration groups are sharing their management adaptations made in response to the pandemic. The present narrative review summarizes the current recommendations. Relevance:  There is a need to define which patients are candidates for safe treatment delay until the pandemic is over or controlled, to reduce exposure to the virus in the healthcare personnel and patients.   Conclusions:  Telemedicine is recommended for follow-up visits. Active surveillance is the preferred treatment for patients with favorable intermediate risk. In greater risk disease, hormone therapy safely postpones radiotherapy up to 7 months. Radiosurgery is suggested in centers that have the necessary technology and previous experience.  A moderately hypofractionated regimen is recommended if radiosurgery/ultra-hypofractionation is not available. Hypofractionation should be implemented if image-guided radiation therapy is already in place. Countries with low and middle-income economies face challenges in adopting the recommendations for prostate cancer management during the pandemic. Postponing treatment may result in the overwhelming of radiation oncology center capacity, after the pandemic.    

scholarly journals Solitary Lung Metastasis of Prostate Cancer with a Long Disease-Free Interval and Normal Prostate-Specific Antigen Level

2021 ◽  
pp. 284-289
Author(s):  
Hiroyuki Yoshitake ◽  
Shoji Oura ◽  
Tomoyuki Yamaguchi ◽  
Shinichiro Makimoto
Keyword(s):  
Prostate Cancer ◽  
Prostate Specific Antigen ◽  
Lung Metastasis ◽  
Specific Antigen ◽  
Middle Lobe ◽  
Primary Adenocarcinoma ◽  
Wide Resection ◽  
Normal Prostate ◽  
Solid Nodule

An 83-year-old man with core needle biopsy-proven Gleason score 5 prostate cancer had received radiotherapy including 18 Gy brachytherapy to the prostate cancer, leading to no locoregional and distant recurrence for more than 5 years with the normalization of elevated prostate-specific antigen (PSA) level before the radiotherapy. Due to the enlargement of coexisting ground glass nodule (GGN) in the left lung from 1 to 2.1 cm, the patient underwent wide resection of the GGN 7 years later. Under the diagnosis of adenocarcinoma in situ of the lung, follow-up computed tomography 6 months after the wide resection showed a rapid enlargement of a solid nodule having been judged as a presumed inflammatory nodule in the middle lobe, highly suggesting a malignant neoplasm of the lung. Due to both the tall columnar atypical cells with trabecular pattern on frozen section and no elevation of serum PSA level, we judged the nodule as a primary adenocarcinoma of the lung and further resected the middle lobe with lymph node dissection. Immunostaining of the tumor showed all the CK7, CK20, TTF-1, napsin A, synaptophysin, chromogranin, CD56, CDX2, p53, beta-catenin, and MUC2 negative, and PSA highly positive, clearly showing the solid nodule as a solitary lung metastasis of the prostate cancer. Physicians should note the possible solitary lung metastasis of prostate cancer, especially bearing indolent biology, with no elevation of the PSA level even after the completion of standard 5-year follow-up.

The importance of targeting intracrinology in prostate cancer management

2018 ◽  
Vol 37 (5) ◽  
pp. 751-757
Author(s):  
Agus Rizal A. H. Hamid ◽  
William Tendi ◽  
Saras Serani Sesari ◽  
Chaidir A. Mochtar ◽  
Rainy Umbas ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Management ◽  
Prostate Cancer Management
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