Synthesis and QSAR Modeling of Novel Benzimidazolo Thiazolidinones, Thiazinones and 5-arylidene-2-imino Thiazolidinones as Antibacterial Agents

2013 ◽  
Vol 9 (3) ◽  
pp. 474-485 ◽  
Author(s):  
Manjunath Ghate ◽  
Praveena Devi ◽  
Jignesh Parikh ◽  
Vivek K. Vyas
Keyword(s):  
Antibacterial Agents ◽  
Qsar Modeling

Synthesis and QSAR modeling of 2-acetyl-2-ethoxycarbonyl-1-[4(4′-arylazo)-phenyl]-N,N-dimethylaminophenyl aziridines as potential antibacterial agents

2009 ◽  
Vol 44 (1) ◽  
pp. 251-259 ◽  
Author(s):  
Pratibha Sharma ◽  
Ashok Kumar ◽  
Siya Upadhyay ◽  
Vinita Sahu ◽  
Jitendra Singh
Keyword(s):  
Antibacterial Agents ◽  
Qsar Modeling

QSAR modeling of synthesized 3-(1,3-benzothiazol-2-yl) 2-phenyl quinazolin-4(3H)-ones as potent antibacterial agents

2011 ◽  
Vol 21 (7) ◽  
pp. 1136-1148 ◽  
Author(s):  
Pratibha Sharma ◽  
Ashok Kumar ◽  
Prerna Kumari ◽  
Jitendra Singh ◽  
M. P. Kaushik
Keyword(s):  
Antibacterial Agents ◽  
Qsar Modeling

Synthesis and QSAR modeling 1-[3-methyl-2-(aryldiazenyl)-2H-aziren-2-yl]ethanones as potential antibacterial agents

2012 ◽  
Vol 22 (5) ◽  
pp. 2476-2485 ◽  
Author(s):  
Vinita Sahu ◽  
Pratibha Sharma ◽  
Ashok Kumar
Keyword(s):  
Antibacterial Agents ◽  
Qsar Modeling

3D QSAR Modeling and Molecular Docking Studies on a Series of Triazole Analogues as Antibacterial Agents

2018 ◽  
Vol 59 (7) ◽  
pp. 1544-1554
Author(s):  
A. Ghaleb ◽  
A. Aouidate ◽  
A. Sbai ◽  
M. Bouachrine ◽  
T. Lakhlifi
Keyword(s):  
Molecular Docking ◽  
Antibacterial Agents ◽  
3D Qsar ◽  
Docking Studies ◽  
Qsar Modeling ◽  
Molecular Docking Studies

ChemInform Abstract: Synthesis and QSAR Modeling of 2-Acetyl-2-ethoxycarbonyl-1- [4(4′-arylazo)-phenyl]-N,N-dimethylaminophenyl Aziridines as Potential Antibacterial Agents.

ChemInform ◽  
2009 ◽  
Vol 40 (20) ◽  
Author(s):  
Pratibha Sharma ◽  
Ashok Kumar ◽  
Siya Upadhyay ◽  
Vinita Sahu ◽  
Jitendra Singh
Keyword(s):  
Antibacterial Agents ◽  
Qsar Modeling

Dermatitis in pets: Study of Brazilian savannah plants as potential antibacterial agents

Planta Medica ◽  
2014 ◽  
Vol 80 (16) ◽  
Author(s):  
AC Valle ◽  
L Rabelo ◽  
AL Magalhães ◽  
M Neves ◽  
I Maciel ◽  
...  
Keyword(s):  
Antibacterial Agents ◽  
Brazilian Savannah

QSAR modeling for predicting carcinogenic potency of nitroso-compounds using 0D-2D molecular descriptors

2007 ◽  
Author(s):  
Maykel González ◽  
Aliuska Helguera ◽  
M. Natália Cordeiro ◽  
Miguel Cabrera Pérez ◽  
Reinaldo Ruiz ◽  
...  
Keyword(s):  
Molecular Descriptors ◽  
Nitroso Compounds ◽  
Qsar Modeling ◽  
Carcinogenic Potency

Discovery of Antibacterial Agents Inhibiting the Energy-Coupling Factor (ECF) Transporters by Structure-Based Virtual Screening

2020 ◽  
Author(s):  
Eleonora Diamanti ◽  
Inda Setyawati ◽  
Spyridon Bousis ◽  
leticia mojas ◽  
lotteke Swier ◽  
...  
Keyword(s):  
Virtual Screening ◽  
Antibacterial Agents ◽  
Antimicrobial Agents ◽  
Energy Coupling ◽  
Coupling Factor ◽  
Design Synthesis ◽  
Screening Design ◽  
Starting Point ◽  
Wide Range ◽  
Vitamin Uptake

Here, we report on the virtual screening, design, synthesis and structure–activity relationships (SARs) of the first class of selective, antibacterial agents against the energy-coupling factor (ECF) transporters. The ECF transporters are a family of transmembrane proteins involved in the uptake of vitamins in a wide range of bacteria. Inhibition of the activity of these proteins could reduce the viability of pathogens that depend on vitamin uptake. Because of their central role in the metabolism of bacteria and their absence in humans, ECF transporters are novel potential antimicrobial targets to tackle infection. The hit compound’s metabolic and plasma stability, the potency (20, MIC Streptococcus pneumoniae = 2 µg/mL), the absence of cytotoxicity and a lack of resistance development under the conditions tested here suggest that this scaffold may represent a promising starting point for the development of novel antimicrobial agents with an unprecedented mechanism of action.<br>

RESULTS OF ENDODONTIC APPLICATION OF VARIOUS ANTIBACTERIAL AGENTS AND CLINICAL AND MICROBIOLOGICAL FEATURES

2019 ◽  
pp. 51-53
Author(s):  
D. S. Tulanov ◽  
S. K. Dalimova ◽  
N. I. Juraeva ◽  
S. R. Mamarasulova
Keyword(s):  
Antibacterial Agents
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