scholarly journals The Natural History of Food Sensitization in Children With Atopic Dermatitis and the Prognostic Role of Specific Serum IgE

2013 ◽  
Vol 7 (1) ◽  
pp. 22-28
Author(s):  
Arianna Giannetti ◽  
Giampaolo Ricci ◽  
Arianna Dondi ◽  
Valentina Piccinno ◽  
Federica Bellini ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Natural History ◽  
School Age ◽  
Food Tolerance ◽  
Serum Ige ◽  
Specific Serum ◽  
Hen’S Egg ◽  
History Of ◽  
Before School

Background: The natural history and the prognostic factors for food tolerance in childhood atopic dermatitis(AD) are poorly understood. Objective: We aimed at investigating the natural course of egg and milk allergy in children affected by AD and food allergy and identifying if the persistence of allergy is associated with high specific serum IgE(sIgE). Methods: The retrospective study included 58 patients affected by AD, aged 9-16 months, with a first clinical examination between 1993 and 2002. Results: Patients with AD and allergy to hen’s egg(N=58) or cow’s milk(N=44) were studied. In most patients milk and egg tolerance was reached before school age, but it was achieved later in children with severe AD and high egg sIgE. Conclusions: The food tolerance is normally reached before school age and, at the time of diagnosis, levels of sIgE>5kU/L for hen’s egg are risk factors for a later tolerance achievement.

scholarly journals Natural History of Excessive Daytime Sleepiness: Role of Obesity, Weight Loss, Depression, and Sleep Propensity

SLEEP ◽  
2015 ◽  
Vol 38 (3) ◽  
pp. 351-360 ◽  
Author(s):  
Julio Fernandez-Mendoza ◽  
Alexandros N. Vgontzas ◽  
Ilia Kritikou ◽  
Susan L. Calhoun ◽  
Duanping Liao ◽  
...  
Keyword(s):  
Weight Loss ◽  
Natural History ◽  
Excessive Daytime Sleepiness ◽  
Daytime Sleepiness ◽  
History Of ◽  
Sleep Propensity

The natural history of sleep disturbance among OEF/OIF veterans with TBI and PTSD and the role of proxy variables in its measurement

2017 ◽  
Vol 96 ◽  
pp. 60-66 ◽  
Author(s):  
Paul R. King ◽  
Kerry T. Donnelly ◽  
Gary Warner ◽  
Michael Wade ◽  
Wilfred R. Pigeon
Keyword(s):  
Natural History ◽  
Sleep Disturbance ◽  
Proxy Variables ◽  
History Of

scholarly journals Role of Endothelial Shear Stress in the Natural History of Coronary Atherosclerosis and Vascular Remodeling

2007 ◽  
Vol 49 (25) ◽  
pp. 2379-2393 ◽  
Author(s):  
Yiannis S. Chatzizisis ◽  
Ahmet Umit Coskun ◽  
Michael Jonas ◽  
Elazer R. Edelman ◽  
Charles L. Feldman ◽  
...  
Keyword(s):  
Shear Stress ◽  
Natural History ◽  
Vascular Remodeling ◽  
Coronary Atherosclerosis ◽  
History Of ◽  
Endothelial Shear Stress

Effects of long-term chloroquine administration on the natural history of aortic aneurysms in mice

2015 ◽  
Vol 93 (8) ◽  
pp. 641-648 ◽  
Author(s):  
Azza Ramadan ◽  
Mark D. Wheatcroft ◽  
Adrian Quan ◽  
Krishna K. Singh ◽  
Fina Lovren ◽  
...  
Keyword(s):  
Natural History ◽  
Thrombus Formation ◽  
Aortic Aneurysms ◽  
Ang Ii ◽  
Abdominal Aortic ◽  
Suprarenal Aorta ◽  
History Of ◽  
Categorical Distribution

Autophagy regulates cellular homeostasis and integrates the cellular pro-survival machinery. We investigated the role of autophagy in the natural history of murine abdominal aortic aneurysms (AAA). ApoE−/− mice were implanted with saline- or angiotensin II (Ang-II)-filled miniosmotic pumps then treated with either the autophagy inhibitor chloroquine (CQ; 50 mg·(kg body mass)–1·day–1, by intraperitoneal injection) or saline. Ang-II-elicited aneurysmal expansion of the suprarenal aorta coupled with thrombus formation were apparent 8 weeks later. CQ had no impact on the incidence (50% for Ang-II compared with 46.2% for Ang-II + CQ; P = NS) and categorical distribution of aneurysms. The markedly reduced survival rate observed with Ang-II (57.1% for Ang-II compared with 100% for saline; P < 0.05) was unaffected by CQ (61.5% for Ang-II + CQ; P = NS compared with Ang-II). CQ did not affect the mean maximum suprarenal aortic diameter (1.91 ± 0.19 mm for Ang-II compared with 1.97 ± 0.21 mm for Ang-II + CQ; P = NS). Elastin fragmentation, collagen accumulation, and smooth muscle attrition, which were higher in Ang-II-treated mice, were unaffected by CQ treatment. Long-term CQ administration does not affect the natural history and prognosis of experimental AAA, suggesting that global loss of autophagy is unlikely to be a causal factor in the development of aortic aneurysms. Manipulation of autophagy as a mechanism to reduce AAA may need re-evaluation.

scholarly journals Natural history of immediate-type hen's egg allergy in Japanese children

2016 ◽  
Vol 65 (2) ◽  
pp. 153-157 ◽  
Author(s):  
Kiyotaka Ohtani ◽  
Sakura Sato ◽  
Akinori Syukuya ◽  
Tomoyuki Asaumi ◽  
Kiyotake Ogura ◽  
...  
Keyword(s):  
Natural History ◽  
Egg Allergy ◽  
Japanese Children ◽  
Hen’S Egg ◽  
History Of

scholarly journals To what extent is social inequality in school-age achievement determined before and during schooling? A longitudinal analysis in three European countries

2020 ◽  
Author(s):  
Giampiero Passaretta ◽  
Jan Skopek ◽  
Thomas van Huizen
Keyword(s):  
Measurement Error ◽  
Social Inequality ◽  
Instrumental Variable ◽  
School Age ◽  
Formal Schooling ◽  
School Life ◽  
Primary Schooling ◽  
The United Kingdom ◽  
Before School

We estimate the degree to which socioeconomic status (SES) gaps in children’s language skills observed in primary schooling are already determined before children enter school in Germany, the Netherlands, and the United Kingdom. We use representative and longitudinal cohort data and apply instrumental variable estimation to deal with measurement error in test scores. Around 60–80% of SES gaps in language at the end of primary school are attributable to gaps settled before formal schooling, while at most 20–40% is attributable to SES operating during the school years. We also show that ignoring measurement error results in a major overestimation of the role of SES during schooling. Our findings suggest that the most effective strategy for reducing social inequality in school-age achievement is reducing inequality before school life starts.

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