Overlaps in the Nosology of Substance Abuse and Overeating: The Translational Implications of “Food Addiction”

2011 ◽  
Vol 4 (3) ◽  
pp. 133-139 ◽  
Author(s):  
Nicole M. Avena ◽  
Miriam E. Bocarsly ◽  
Bartley G. Hoebel ◽  
Mark S. Gold
Antioxidants ◽  
2020 ◽  
Vol 9 (5) ◽  
pp. 425
Author(s):  
Nady Braidy ◽  
Maria D. Villalva ◽  
Sam van Eeden

Nicotinamide adenine dinucleotide (NAD+) is an essential pyridine nucleotide that has garnered considerable interest in the last century due to its critical role in cellular processes associated with energy production, cellular protection against stress and longevity. Research in NAD+ has been reinvigorated by recent findings that components of NAD+ metabolism and NAD-dependent enzymes can influence major signalling processes associated with the neurobiology of addiction. These studies implicate raising intracellular NAD+ levels as a potential target for managing and treating addictive behaviour and reducing cravings and withdrawal symptoms in patients with food addiction and/or substance abuse. Since clinical studies showing the use of NAD+ for the treatment of addiction are limited, this review provides literature evidence that NAD+ can influence the neurobiology of addiction and may have benefits as an anti-addiction intervention.


2005 ◽  
Vol 39 (6) ◽  
pp. 6-7
Author(s):  
DOUG BRUNK
Keyword(s):  

2005 ◽  
Vol 38 (11) ◽  
pp. 35
Author(s):  
Kevin Foley
Keyword(s):  

Author(s):  
Tilman Wetterling ◽  
Klaus Junghanns

Abstract. Aim: This study investigates the characteristics of older patients with substance abuse disorders admitted to a psychiatric department serving about 250.000 inhabitants. Methods: The clinical diagnoses were made according to ICD-10. The data of the patients with substance abuse were compared to a matched sample of psychiatric inpatients without substance abuse as well as to a group of former substance abusers with long-term abstinence. Results: 19.3 % of the 941 patients aged > 65 years showed current substance abuse, 9.4 % consumed alcohol, 7.9 % took benzodiazepines or z-drugs (zolpidem and zopiclone), and 7.0 % smoked tobacco. Multiple substance abuse was rather common (30.8 %). About 85 % of the substance abusers had psychiatric comorbidity, and about 30 % showed severe withdrawal symptoms. As with the rest of the patients, somatic multimorbidity was present in about 70 % of the substance abusers. Remarkable was the lower rate of dementia in current substance abusers. Conclusion: These results underscore that substance abuse is still a challenge in the psychiatric inpatient treatment of older people.


Sign in / Sign up

Export Citation Format

Share Document