scholarly journals The Role of Environmental Control Measures in Asthmatic Children Who are Sensitized to House Dust Mites

2016 ◽  
Vol 14 (1) ◽  
pp. 10-17
Author(s):  
Makbule Ercan ◽  
Enes Kaymak ◽  
Mutlu Yüksek
Keyword(s):  
House Dust ◽  
Environmental Control ◽  
Control Measures ◽  
House Dust Mites ◽  
Dust Mites ◽  
Asthmatic Children

Impact of Sublingual Immunotherapy on Specific Antibody Levels in Asthmatic Children Allergic to House Dust Mites

2005 ◽  
Vol 136 (3) ◽  
pp. 287-294 ◽  
Author(s):  
Nerin N. Bahceciler ◽  
Cigdem Arikan ◽  
Alison Taylor ◽  
Mubeccel Akdis ◽  
Kurt Blaser ◽  
...  
Keyword(s):  
House Dust ◽  
Specific Antibody ◽  
Sublingual Immunotherapy ◽  
House Dust Mites ◽  
Dust Mites ◽  
Asthmatic Children ◽  
Antibody Levels

scholarly journals Group 10 Allergens (Tropomyosins) from House-Dust Mites May Cause Covariation of Sensitization to Allergens from Other Invertebrates

2012 ◽  
Vol 3 (2) ◽  
pp. ar.2012.3.0036 ◽  
Author(s):  
Rubaba Hamid Shafique ◽  
Muhammad Inam ◽  
Muhammad Ismail ◽  
Farhana Riaz Chaudhary
Keyword(s):  
House Dust ◽  
Cross Reactivity ◽  
Amino Acid Sequences ◽  
House Dust Mites ◽  
Published Data ◽  
Dust Mites ◽  
Cockroach Allergen ◽  
Ige Binding ◽  
Group 10

Group 10 allergens (tropomyosins) have been assumed to be a major cause of cross-reactivity between house-dust mites (HDMs) and other invertebrates. Despite all of the published data regarding the epidemiology, percent IgE binding and level of sensitization in the population, the role of tropomyosin as a cross-reactive allergen in patients with multiple allergy syndrome still remains to be elucidated. Homology between amino acid sequences reported in allergen databases of selected invertebrate tropomyosins was determined with Der f 10 as the reference allergen. The 66.9 and 54.4% identities were found with selected crustacean and insect species, respectively, whereas only 20.4% identity was seen with mollusks. A similar analysis was performed using reported B-cell IgE-binding epitopes from Met e1 (shrimp allergen) and Bla g7 (cockroach allergen) with other invertebrate tropomyosins. The percent identity in linear sequences was higher than 35% in mites, crustaceans, and cockroaches. The polar and hydrophobic regions in these groups were highly conserved. These findings suggest that tropomyosin may be a major cause of covariation of sensitization between HDMs, crustaceans, and some species of insects and mollusks.

179 Sensitization to house dust mites in asthmatic children in Argentina and cross-reactivity studies

1996 ◽  
Vol 97 (1) ◽  
pp. 227-227
Author(s):  
C BAENACAGNANI ◽  
E FERNANDEZCALDAS ◽  
L ARLIAN ◽  
R CODINA ◽  
M CUELLO ◽  
...  
Keyword(s):  
House Dust ◽  
Cross Reactivity ◽  
House Dust Mites ◽  
Dust Mites ◽  
Asthmatic Children

scholarly journals Role of house-dust mites in childhood asthma

1974 ◽  
Vol 49 (9) ◽  
pp. 711-715 ◽  
Author(s):  
J. K. Sarsfield
Keyword(s):  
House Dust ◽  
Childhood Asthma ◽  
House Dust Mites ◽  
Dust Mites

scholarly journals Association between house dust mites sensitization and level of asthma control and severity in children attending Mansoura University Children’s Hospital

2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Nahla Mohamed Okasha ◽  
Amr Ali Sarhan ◽  
Engy Osman Ahmed
Keyword(s):  
Asthma Control ◽  
House Dust ◽  
Asthma Severity ◽  
House Dust Mites ◽  
Dust Mites ◽  
Asthma Phenotype ◽  
Asthmatic Children ◽  
Significant Difference ◽  
Control Asthma ◽  
Gina Guidelines

Abstract Background House dust mites (HDM) are considered as a major source of indoor aeroallergen all over the world that precipitate allergic reactions including rhinoconjunctivitis, food allergy, atopic dermatitis, and allergic asthma. In this study, we aimed to assess the clinical and laboratory profile of some Egyptian asthmatic children who are sensitized to house dust mites and determine the association of HDM sensitization and severity of asthma according to recent GINA guidelines. Results The most frequent clinical phenotype among the HDM-positive group was a cough (96.7%), while the clinical phenotypic wheeze was frequent in HDM negative group (96.7%). There is a statistically significant difference between studied cases classified according to sensitivity to HDM regarding level of asthma control (50.0% were uncontrolled among cases sensitive to HDM and 56.7% of cases non-sensitive to HDM were controlled (p = 0.001*). Severity according to treatment results was significantly higher among cases sensitive to HDM (26.7% of cases sensitive to HDM versus 3.3% of cases non-sensitive to HDM), p = 0.017. Conclusions HDM sensitization is associated mainly with cough asthma phenotype and allergic rhinitis in our studied cases. HDM sensitization increases asthma severity and decreases the ability to control asthma symptoms. Trial registration ClinicalTrial.gov, NCT04958616.

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