scholarly journals Virtual Reality Cognitive Training in Individuals with Alcohol Use Disorder Undergoing Residential Treatment: A Pilot Randomized Controlled Trial (Preprint)

10.2196/18482 ◽  
2020 ◽  
Author(s):  
Pedro Gamito ◽  
Jorge Oliveira ◽  
Marcelo Matias ◽  
Elsa Cunha ◽  
Rodrigo Brito ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Virtual Reality ◽  
Alcohol Use ◽  
Residential Treatment ◽  
Cognitive Training ◽  
Alcohol Use Disorder ◽  
Controlled Trial ◽  
Randomized Controlled ◽  
Pilot Randomized Controlled Trial

scholarly journals Virtual Reality Cognitive Training in Individuals with Alcohol Use Disorder Undergoing Residential Treatment: A Pilot Randomized Controlled Trial (Preprint)

2020 ◽  
Author(s):  
Pedro Gamito ◽  
Jorge Oliveira ◽  
Marcelo Matias ◽  
Elsa Cunha ◽  
Rodrigo Brito ◽  
...  
Keyword(s):  
Virtual Reality ◽  
Alcohol Use ◽  
Cognitive Training ◽  
Cognitive Flexibility ◽  
Alcohol Use Disorder ◽  
Controlled Trial ◽  
Treatment As Usual ◽  
Randomized Controlled ◽  
Global Cognition ◽  
Pilot Randomized Controlled Trial

BACKGROUND Alcohol use disorder has been associated with diverse physical and mental morbidities. Among the main consequences of chronic and excessive alcohol use are cognitive and executive deficits. Some of these deficits may be reversed in specific cognitive and executive domains with behavioral approaches consisting in cognitive training. The advent of computer-based interventions may leverage these improvements, but RCTs of digital interactive-based interventions are still scarce. OBJECTIVE The aim is to explore whether a cognitive training approach using virtual reality exercises based on activities of daily living is feasible for improving cognitive function of patients with alcohol use disorder undergoing residential treatment, as well as to estimate the effect size for this intervention to power future definitive RCTs. METHODS A two-arm pilot randomized controlled trial with a sample of 36 individuals recovering from alcohol use disorder in a therapeutic community assigned to a therapist-guided virtual reality-based cognitive training combined with treatment-as-usual or a control group with treatment-as-usual without cognitive training. A comprehensive neuropsychological battery of tests was used both at pre and post assessments, including global cognition, executive functions, attention, visual memory and cognitive flexibility. RESULTS In order to control for potential effects of global cognition and executive functions at baseline, these domains were controlled in the statistical analysis for each individual outcome. Results indicate effects (P < .05) of the intervention on attention (in 2 out of 5 outcomes) and cognitive flexibility (in 2 out of 6 outcomes), with effect sizes in significant comparisons being larger for attention than for cognitive flexibility. Patient retention in cognitive training was high, in line with previous studies. CONCLUSIONS Overall data suggest specific contributions of reality-based cognitive training in improving attention ability and cognitive flexibility of patients recovering from alcohol use disorder. CLINICALTRIAL ClinicalTrials.gov NCT04505345; https://clinicaltrials.gov/show/NCT04505345

scholarly journals A randomized controlled trial of a virtual reality based, approach-avoidance training program for alcohol use disorder: a study protocol

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Angelina Isabella Mellentin ◽  
Anette Søgaard Nielsen ◽  
Leonie Ascone ◽  
Janina Wirtz ◽  
Jerzy Samochowiec ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Virtual Reality ◽  
Alcohol Use ◽  
Training Program ◽  
Study Protocol ◽  
Alcohol Use Disorder ◽  
Avoidance Training ◽  
Controlled Trial ◽  
Randomized Controlled ◽  
Approach Avoidance

scholarly journals Virtual Reality-Based Cognitive Stimulation on People with Mild to Moderate Dementia due to Alzheimer’s Disease: A Pilot Randomized Controlled Trial

2021 ◽  
Vol 18 (10) ◽  
pp. 5290
Author(s):  
Jorge Oliveira ◽  
Pedro Gamito ◽  
Teresa Souto ◽  
Rita Conde ◽  
Maria Ferreira ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Randomized Controlled Trial ◽  
Virtual Reality ◽  
Cognitive Function ◽  
Controlled Trial ◽  
Cognitive Stimulation ◽  
Randomized Controlled ◽  
Moderate Dementia ◽  
Pilot Randomized Controlled Trial

The use of ecologically oriented approaches with virtual reality (VR) depicting instrumental activities of daily living (IADL) is a promising approach for interventions on acquired brain injuries. However, the results of such an approach on dementia caused by Alzheimer’s disease (AD) are still lacking. This research reports on a pilot randomized controlled trial that aimed to explore the effect of a cognitive stimulation reproducing several IADL in VR on people with mild-to-moderate dementia caused by AD. Patients were recruited from residential care homes of Santa Casa da Misericórdia da Amadora (SCMA), which is a relevant nonprofit social and healthcare provider in Portugal. This intervention lasted two months, with a total of 10 sessions (two sessions/week). A neuropsychological assessment was carried out at the baseline and follow-up using established neuropsychological instruments for assessing memory, attention, and executive functions. The sample consisted of 17 patients of both genders randomly assigned to the experimental and control groups. The preliminary results suggested an improvement in overall cognitive function in the experimental group, with an effect size corresponding to a large effect in global cognition, which suggests that this approach is effective for neurocognitive stimulation in older adults with dementia, contributing to maintaining cognitive function in AD.

scholarly journals Development and Testing of a Virtual Reality Mirror Therapy System for the Sensorimotor Performance of Upper Extremity: A Pilot Randomized Controlled Trial

IEEE Access ◽  
2021 ◽  
Vol 9 ◽  
pp. 14725-14734
Author(s):  
Che-Wei Lin ◽  
Li-Chieh Kuo ◽  
Yu-Ching Lin ◽  
Fong-Chin Su ◽  
Yu-An Lin ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Virtual Reality ◽  
Upper Extremity ◽  
Controlled Trial ◽  
Mirror Therapy ◽  
Randomized Controlled ◽  
Pilot Randomized Controlled Trial ◽  
Sensorimotor Performance

scholarly journals Doxazosin for the treatment of co-occurring PTSD and alcohol use disorder: Design and methodology of a randomized controlled trial in military veterans

2018 ◽  
Vol 73 ◽  
pp. 8-15 ◽  
Author(s):  
Sudie E. Back ◽  
Julianne C. Flanagan ◽  
Jennifer L. Jones ◽  
Isabel Augur ◽  
Alan L. Peterson ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Alcohol Use ◽  
Alcohol Use Disorder ◽  
Controlled Trial ◽  
Military Veterans ◽  
Randomized Controlled
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