The effect of acellular dermal matrix therapy on biphasic calsium sulfate bone graft

Infrabony pocket therapy is needed to eliminate pocket wall, creating easy to clean conditions for new attachment, and bone regeneration. Biphasic calcium sulfate (BCS) bone grafts combined with collagen membranes are known to regenerate bone tissue and have good osteoconductive effects. The addition of collagen membranes promotes migration and proliferation of fibroblast cells, osteoblasts, and homeostasis. However, the collagen membrane is a rapidbioresynthesis and may cause disease transmission from animal. Acellular dermal matrix (ADMA) membrane contains a bioactive matrix that has the ability to support normal revascularization, cell repopulation, and tissue remodeling. Combination of BCS with ADMA membrane are proven to induce bone and tissue regeneration. The objective of this study is to determine the therapeutic effect of BSC and ADMA combination to eradicate pocket, gingival recession, bone recession and attachment loss. The samples were taken from 20 infrabony pocket sites divided into 2 groups. The first was treated by combination of BCS and ADMA, while the second group was treated by the combination of BCS and collagen membrane. After 1 and 3 months of flap surgery, the result was observed by probing depth(PD), relative attachment loss (RAL), gingival recession, alveolar bone height and radiological examination. The result showed the decrease of PD, RAL, gingival recession, and alveolar bone height in both two groups. However, there wereno significant differences between those two groups. In conclusion, the combination of BCS and ADMA or BCS and collagen decreased the PD, RAL, gingival recession and alveolar bone height.

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ROOT COVERAGE USING THE SUBEPITHELIAL CONNECTIVE TISSUE GRAFT OR THE ACELLULAR DERMAL MATRIX FOR THE TREATMENT OF GINGIVAL RECESSION: A CLINICAL STUDY

International Journal of Applied Pharmaceutics ◽

10.22159/ijap.2017.v9s2.06 ◽

2018 ◽

Vol 9 ◽

pp. 20

Author(s):

Shula Zuleika Sumana ◽

Sri Lelyati C Masulili ◽

Robert Lessang

Keyword(s):

Connective Tissue ◽

Acellular Dermal Matrix ◽

Gingival Recession ◽

Root Coverage ◽

Dermal Matrix ◽

Connective Tissue Graft ◽

Tissue Graft ◽

Operative Data ◽

Subepithelial Connective Tissue Graft ◽

Acellular Dermal

Objective: This study aims to evaluate periodontal clinical conditions after treatment for gingival recession (GR) using subepithelial connective tissue graft (SCTG) and acellular dermal matrix (ADM).Methods: Ten patients with Miller’s Class I and II recessions that had been treated with SCTG or ADM at the Periodontics Outpatient Department at Universitas Indonesia were selected for this study. The pre-operative data for GR, clinical attachment levels (CAL), and attached gingiva (AG) were retrieved from the patients’ medical records. The patients were recalled and the post-operative data were recorded.Results: The application of SCTG and ADM yields significant changes to GR, CAL, and AG levels. A comparison of two groups at the post-operative assessment stage showed no statistically significant differences, in terms of GR, CAL, and AG.Conclusion: SCTG and ADM yield similar outcomes in the treatment of GR. As such, ADM may be suggested as an alternative to SCTG for root coverage.

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Treatment of Exposed Bone With Acellular Dermal Matrix in a Smoker Patient After Dental Implant Surgery: A Case Report

Journal of Oral Implantology ◽

10.1563/aaid-joi-d-19-00221 ◽

2019 ◽

Vol 46 (3) ◽

pp. 245-249

Author(s):

Levent Cigerim

Keyword(s):

Case Report ◽

Dental Implant ◽

Acellular Dermal Matrix ◽

Gingival Recession ◽

Dermal Matrix ◽

Attached Gingiva ◽

Exposed Bone ◽

Dermal Cells ◽

Dental Implant Surgery ◽

Acellular Dermal

Acellular dermal matrix is a biocompatible material derived from human and animal connective tissue. This material is created by a chemical process in which all epidermal and dermal cells are removed but the bioactive dermal matrix is left intact. The bioactive dermal matrix has the capability to promote natural revascularization and cell repopulation and to undergo tissue remodeling as it contains elastin, collagen, bioactive proteins, and blood vessel channels. Recently, ADM materials have successfully been used as grafts in numerous surgical procedures to increase the size of the attached gingiva surrounding the teeth and implants, to fill in gingival recession defects to enhance root coverage, to manage soft-tissue ridge deformities, and to repair oronasal fistulae. The aim of this case report is to evaluate the use of the acellular dermal matrix in a 45-year-old patient with an area of exposed bone after the placement of a dental implant.

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Modified tunnel technique for management of gingival recession in esthetic zone using acellular dermal matrix versus connective tissue graft

Future Dental Journal ◽

10.1016/j.fdj.2018.12.001 ◽

2018 ◽

Cited By ~ 1

Author(s):

Rania A. Fahmy ◽

Maha R. Taalab

Keyword(s):

Connective Tissue ◽

Acellular Dermal Matrix ◽

Gingival Recession ◽

Matrix Versus ◽

Dermal Matrix ◽

Connective Tissue Graft ◽

Tissue Graft ◽

Tunnel Technique ◽

Acellular Dermal

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Acellular Dermal Matrix Seeded With Autologous Gingival Fibroblasts for the Treatment of Gingival Recession: A Proof-of-Concept Study

Journal of Periodontology ◽

10.1902/jop.2009.090530 ◽

2010 ◽

Vol 81 (4) ◽

pp. 616-625 ◽

Cited By ~ 39

Author(s):

Hiral M. Jhaveri ◽

Mahesh S. Chavan ◽

Geetanjali B. Tomar ◽

Vijay L. Deshmukh ◽

Mohan R. Wani ◽

...

Keyword(s):

Acellular Dermal Matrix ◽

Gingival Recession ◽

Proof Of Concept ◽

Gingival Fibroblasts ◽

Dermal Matrix ◽

Concept Study ◽

Acellular Dermal

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Efficacy of Acellular Dermal Matrix and Coronally Advanced Flaps for the Treatment of Induced Gingival Recession Defects: A Histomorphometric Study in Dogs

Journal of Periodontology ◽

10.1902/jop.2012.120380 ◽

2013 ◽

Vol 84 (8) ◽

pp. 1172-1179 ◽

Cited By ~ 6

Author(s):

Khalid Al-Hezaimi ◽

Ivan Rudek ◽

Khalid Saleh Al-Hamdan ◽

Fawad Javed ◽

Giovanna Iezzi ◽

...

Keyword(s):

Acellular Dermal Matrix ◽

Gingival Recession ◽

Dermal Matrix ◽

Histomorphometric Study ◽

Acellular Dermal

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Comparative 6-Month Clinical Study of a Subepithelial Connective Tissue Graft and Acellular Dermal Matrix Graft for the Treatment of Gingival Recession

Journal of Periodontology ◽

10.1902/jop.2001.72.11.1477 ◽

2001 ◽

Vol 72 (11) ◽

pp. 1477-1484 ◽

Cited By ~ 74

Author(s):

Arthur B. Novaes ◽

Daniela C. Grisi ◽

Gustavo O. Molina ◽

Sérgio L.S. Souza ◽

Mario Taba ◽

...

Keyword(s):

Clinical Study ◽

Connective Tissue ◽

Acellular Dermal Matrix ◽

Gingival Recession ◽

Dermal Matrix ◽

Connective Tissue Graft ◽

Tissue Graft ◽

Subepithelial Connective Tissue Graft ◽

Acellular Dermal

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Comparative Clinical Evaluation of Acellular Dermal Matrix Allograft and Connective Tissue Graft for the Treatment of Gingival Recession

The Journal of Contemporary Dental Practice ◽

10.5005/jcdp-7-2-63 ◽

2006 ◽

Vol 7 (2) ◽

pp. 63-70 ◽

Cited By ~ 15

Author(s):

M.E. Rahmani ◽

Mohammad A. Rigi Lades

Keyword(s):

Connective Tissue ◽

Clinical Evaluation ◽

Acellular Dermal Matrix ◽

Gingival Recession ◽

Dermal Matrix ◽

Connective Tissue Graft ◽

Tissue Graft ◽

Post Surgery ◽

Attached Gingiva ◽

Acellular Dermal

Abstract Aims “Gingival recession is a condition reported to occur due to abnormal periodontal anatomy, poor hygiene, excessive occlusal forces, toothbrush abrasion, and even iatrogenic or factitious causes. Though various surgical techniques are available to treat this problem, the most common is the palatal soft tissue autograft. Recently, an acellular dermal matrix allograft (ADMA) has been available as a substitute for the palatal tissue harvest. The aim of this study is to compare the ADMA with the conventional subepithelial connective tissue graft (SCTG) in the treatment of gingival recession.” Methods and Materials Fourteen patients with 20 gingival recessions of Miller's grade I and II were selected and randomized in two groups of control (SCTG) and test (ADMA). In each group ten recession defects were treated. The following parameters were measured at baseline and then at six months post surgery: recession height (RH), recession width (RW), probing depth (PD), attached gingiva (AG), keratinized gingiva (KG), and clinical attachment level (CAL). All parameters were analyzed using the two-sample t-test. Data analysis was performed using SPSS (version 11) software. Results The following mean changes (mm) occurred in SCTG and ADMA, respectively: 2.60±0.97 and 2.90±0.81 decrease in RH; 1.70±1.01 and 1.65±0.67 decrease in RW; 2.50±0.97 and 2.95±0.69 increase in KG; 2.25±0.92 and 2.65±0.85 increase in AG; 2.60±1.08 and 2.75±0.92 decrease in CAL; and finally 0.05±0.50 and 0.10±0.46 decrease in PD for the SCTG and ADMA groups, respectively. The percentage of root coverage for the two groups was 70.12%±22.81% and 72.08%±14.12%, respectively. The changes from baseline to the six-month visit were significant for both groups in terms of all parameters but PD. However, the differences in mean changes were not significant between the two groups in any of the parameters. Conclusion These findings imply the ADMA and SCTG techniques could produce the same results when used for the successful treatment of gingival recessions. In addition the ADMA could be used as an adequate alternative treatment modality for conventional techniques. Citation Rahmani ME, Lades MAR. Comparative Clinical Evaluation of Acellular Dermal Matrix Allograft and Connective Tissue Graft for the Treatment of Gingival Recession. J Contemp Dent Pract 2006 May;(7)2:063-070.

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