scholarly journals Capsaicin 8% patch for peripheral neuropathic pain: review of treatment best practice from ‘real-world’ clinical experience

2012 ◽  
Vol 2 (3) ◽  
pp. 239-250 ◽  
Author(s):  
Till Wagner ◽  
Andrea Roth-Daniek ◽  
Angela Sell ◽  
Janice England ◽  
Kai-Uwe Kern
Keyword(s):  
Neuropathic Pain ◽  
Clinical Experience ◽  
Real World ◽  
Best Practice ◽  
Peripheral Neuropathic Pain

scholarly journals Localized peripheral neuropathic pain: topical treatment with lidocaine 700 mg medicated plaster in routine clinical practice

2022 ◽  
Author(s):  
Michael A Überall ◽  
Irmgard Bösl ◽  
Els Hollanders ◽  
Ingo Sabatschus ◽  
Mariëlle Eerdekens
Keyword(s):  
Neuropathic Pain ◽  
Medical Care ◽  
Real World ◽  
Real World Data ◽  
Good Tolerability ◽  
Peripheral Neuropathic Pain ◽  
Intensity Index ◽  
Oral Medications ◽  
Real World Evidence ◽  
Average Pain

Aim: To provide real-world evidence for the effectiveness and tolerability of lidocaine 700 mg medicated plaster (LMP) in localized peripheral neuropathic pain (l-PNP) treatment compared with first-line oral medications (OM). Patients & methods: This was a noninterventional, retrospective 6-month cohort study in patients refractory to at least one recommended OM, using anonymized medical care data from the German Pain eRegistry. Treatment groups were matched by propensity scoring, considering seven predefined confounding factors. The primary effectiveness end point was the absolute change in average pain intensity index from baseline at weeks 4, 12 and 24 of treatment and over the treatment period. Results: A total of 3081 datasets were retained per treatment group. LMP provided superior pain reductions and significantly greater improvements in pain-related impairments of daily living and quality of life with significantly better tolerability (p < 0.001 for all parameters) than OM. Conclusion: These real-world data confirm the effectiveness and good tolerability of LMP for l-PNP treatment under routine medical care.

The Effect of Blocking of Antidromic Impulses by Capsaicin on Mechanical Allodynia in a Rat Model of Peripheral Neuropathic Pain

2004 ◽  
Vol 17 (1) ◽  
pp. 5 ◽  
Author(s):  
Jin Woo Shin ◽  
Kyung Don Hahm ◽  
Joong Woo Leem ◽  
Chul Hoo Park ◽  
Seung Woo Ku ◽  
...  
Keyword(s):  
Neuropathic Pain ◽  
Rat Model ◽  
Mechanical Allodynia ◽  
Peripheral Neuropathic Pain
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