scholarly journals Clinical Applications of Office-Based Laryngeal Surgery With KTP Laser

Author(s):  
Jung-Hae Cho

The pulsed photoangiolytic 532-nm potassium-titanyl-phosphate (KTP) laser has emerged in recent years as an efficacious treatment modality for vocal fold lesions. It also has broadened the indications for other laryngeal laser surgery. Features of KTP laser that it is a fiber-based delivery system and its energy is selectively absorbed by oxyhemoglobin make it suitable for office-based laryngeal procedures. An office-based KTP laser surgery provides an alternative management option for benign laryngeal diseases and can be performed comfortably under flexible endoscopic guidance which is placed through the nose of a fully awake patient. Office-based laryngeal surgery with a KTP laser can alleviate the need for general anesthesia. However, there are some limitations to apply due to reduced visual precision and the fact that the vocal folds are moving during procedures. Clinicians should carefully weigh the advantages and disadvantages of office-based procedures before a treatment option is selected. Patient selection and standardized laser energy parameters may help in decreasing complications and improving the treatment results.

Author(s):  
Min Seok Kang ◽  
Jae-Yol Lim

There are several lasers available for office-based or suspension microlaryngoscopy laser procedures in the treatment of laryngeal diseases. Each has advantages and disadvantages given the depth of penetration per unit of power, absorption in water, spectral absorption characteristics, mode of delivery, safety, and cost. It is important to note that while the proper selection of indication of treatment based on a laser wavelength is critical, of equal importance is selecting the appropriate power setting, focal length (or spot size), and time of exposure. The photoangiolytic lasers precisely target hemoglobin within the microcirculation of the highly vascularized tissue and may have better hemostatic effects and preservation of surrounding normal tissue than the CO2 laser. Although the choice of laser is purely theoretical and cannot be accurately concluded which parameters of laser (wattage and pulse width) were best to use, photoangiolytic laser surgery is safe and effective for specific laryngeal lesions. In this review, indications for photoangiolytic laser procedures for various laryngeal diseases, laser settings and surgical techniques for specific laryngeal lesions including sulcus vocalis, laryngeal dysplasia, and recurrent respiratory papillomatosis will be introduced. Pros and cons of in-office laser surgery using photoangiolytic laser and flexible CO2 laser will also be addressed.


2009 ◽  
Vol 118 (9) ◽  
pp. 1-24 ◽  
Author(s):  
Steven M. Zeitels ◽  
Gerardo Lopez-Guerra ◽  
James A. Burns ◽  
Matthew Lutch ◽  
Aaron M. Friedman ◽  
...  

Objectives: Photoangiolytic lasers effectively treat glottal papillomatosis, but do not reliably prevent recurrence. Therefore, sublesional injections of the antiangiogenic agent bevacizumab (Avastin) were given to assess the effect on disease recurrence and phonatory function. Methods: A retrospective investigation was done in a pilot group of 10 adult patients with bilateral glottal papillomatosis who had prior angiolytic laser treatment with established patterns of recurrence. The patients underwent 5 bevacizumab injections (5 to 10 mg) into the diseased vocal folds along with 532-nm pulsed KTP laser photoangiolysis treatments 4 to 6 weeks apart. Their disease resolution was compared to findings from prior laser treatment alone, and objective measures of vocal function (acoustic, aerodynamic, Voice-Related Quality of Life survey) were obtained. Results: All 10 patients had a greater than 90% reduction in recurrence. Four of the 10 had resolution. Four of the 10 have limited recurrent or persistent disease, receive injections of bevacizumab at 8- to 12-week intervals, and have not required laser treatment. Two of the 10 have ongoing periodic office-based KTP laser treatment along with bevacizumab injections. No patient has required microlaryngeal surgery with general anesthesia, and all 10 have had substantial improvement in vocal function. Conclusions: This pilot investigation provides preliminary evidence that bevacizumab injections enhance photoangiolytic laser treatment of glottal papillomatosis while enhancing phonatory function. Coupling an antiangiogenesis agent with pulsed KTP laser photoangiolysis is conceptually promising, since the mechanisms of action are complementary.


2013 ◽  
Vol 149 (5) ◽  
pp. 739-744 ◽  
Author(s):  
Carolyn A. Coughlan ◽  
Sunil P. Verma

2013 ◽  
Vol 64 (3) ◽  
pp. 212-218
Author(s):  
Kenichi Watanabe ◽  
Yuuri Okumura ◽  
Koji Hozawa

2001 ◽  
Author(s):  
Jean-Marie Chartier ◽  
Leonid F. Vitushkin ◽  
Mikhail Khaleyev ◽  
Georgii E. Novikov ◽  
Oleg A. Orlov ◽  
...  
Keyword(s):  

2001 ◽  
Vol 124 (4) ◽  
pp. 459-463 ◽  
Author(s):  
David B. Wexler ◽  
Gilead Berger ◽  
Ari Derowe ◽  
Dov Ophir

OBJECTIVE: In this study we sought to define the histologic changes produced by laser treatment of inferior turbinates. STUDY DESIGN: Eight inferior turbinates with prior laser treatment (mean, 26.8 months) were analyzed by light microscopy after turbinectomy for relief of refractory nasal obstruction. Histologic findings were compared with those of a group of 8 hypertrophic inferior turbinates that had no previous laser surgery. RESULTS: Laser-treated areas of the inferior turbinates demonstrated a histologically bland appearance, with marked diminution of seromucinous glands and relative preponderance of connective tissue matrix. Prominence of venous sinusoids was also significantly reduced in the laser-treated areas. Surface epithelium including goblet cells was reconstituted over the areas of laser application. CONCLUSION: Clinical laser surgery of the inferior turbinate produces striking long-term histologic changes. SIGNIFICANCE: The data suggest a differential response of turbinate histologic components to application of laser energy, with the glandular component being particularly sensitive. Further correlative study is needed to clarify the clinical significance of laser-induced histologic changes in inferior turbinates.


1992 ◽  
Vol 101 (1) ◽  
pp. 51-60 ◽  
Author(s):  
Eiji Yanagisawa ◽  
Ken Yanagisawa ◽  
Jay B. Horowitz ◽  
Lawrence J. Mambrino

A new approach to microlaryngeal surgery using a specially designed video microlaryngoscope with a rigid endoscopic telescope and an attached video camera was introduced by Kantor et al in 1990. The ability to video document and perform surgery of the larynx by viewing a high-resolution television image was demonstrated. This method was recommended over the standard microscopic technique for increased visibility with greater depth of field, unimpeded instrument access, instant documentation, and superior teaching value. The authors tried this new method and the standard microscopic technique at the same sitting on a series of patients. This paper will compare these two different techniques and discuss their advantages and disadvantages. Although the new method has many advantages, the standard microscopic technique remains as a valuable method in laryngeal surgery.


2014 ◽  
Vol 2014 ◽  
pp. 1-6
Author(s):  
Bilal Chughtai ◽  
Claire Dunphy ◽  
Alexis Te

Lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia are a bothersome symptom set that affect approximately one in every four males above the age of 50. First line treatment is typically medication, but when medications fail surgical therapy is the next option. Technological advances have made surgical therapy safer and more effective. One area that our group has particular interest and focus in is the application of the 532 nm laser in surgical therapy. The high power 532 nm laser is used to remove obstructive prostatic tissue and the laser energy is selectively absorbed by hemoglobin in the prostate tissue, resulting in effective tissue vaporization and removal. We review our experience with Greenlight laser system and its evolution from the original 60-watt laser to the most recent 180-watt Greenlight system with MoXy fiber.


2011 ◽  
Vol 354-355 ◽  
pp. 1224-1227
Author(s):  
Ru Zheng Pan ◽  
You Hua Wang ◽  
Min Tang Li ◽  
Ling Ling Pang ◽  
Jue Wang ◽  
...  

Based on the platform of laser-triggered surface flashover in pulsed voltage, experiment of laser-triggered surface flashover is carried out in air and vacuum condition with pulsed voltage. A single/double harmonic, with wavelength of 1064/532 nm, Q-switched Nd:YAG laser is applied to trigger the surface flashover. The test system consists of flat electrodes and columned insulator. The material of electrode is copper and the material of insulator is Al2O3. Laser pulse’s wavelengths are 532nm and 1064nm, and laser is focused with rectangle. The results of experiment show that flashover delay time and jitter time decrease with increase of pulsed voltage or laser energy density, the delay time of 1064nm laser trigger is larger than that of 532nm laser trigger, and the delay time and jitter time in vacuum condition are less than the delay time and jitter time in air condition.


Sign in / Sign up

Export Citation Format

Share Document