Successful pembrolizumab treatment of microsatellite instability-high intrahepatic cholangiocarcinoma: A case report

Mapping Intimacies ◽

10.22541/au.161193945.52485364/v1 ◽

2021 ◽

Author(s):

YUKI IKEDA ◽

Michihiro Ono ◽

Ginji Omori ◽

Saki Ameda ◽

Michiko Yamada ◽

...

Keyword(s):

Case Report ◽

Microsatellite Instability ◽

Intrahepatic Cholangiocarcinoma ◽

Effective Therapy

Pembrolizumab is considered to be an effective therapy for patients with microsatellite instability (MSI)-high cancer. Here, we report a case of MSI-high cholangiocarcinoma effectively treated with pembrolizumab. MSI status should be actively evaluated in patients with cholangiocarcinoma.

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Successful pembrolizumab treatment of microsatellite instability‐high intrahepatic cholangiocarcinoma: A case report

Clinical Case Reports ◽

10.1002/ccr3.4008 ◽

2021 ◽

Author(s):

Yuki Ikeda ◽

Michihiro Ono ◽

Ginji Ohmori ◽

Saki Ameda ◽

Michiko Yamada ◽

...

Keyword(s):

Case Report ◽

Microsatellite Instability ◽

Intrahepatic Cholangiocarcinoma

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Diagnostic confusion in paediatric respiratory pathology. Case report

ORL ro ◽

10.26416/orl.30.1.2016.652 ◽

2016 ◽

Vol 1 (1) ◽

pp. 48-50

Author(s):

Adina A. Zamfir-Chiru-Anton ◽

D.C. Gheorghe

Keyword(s):

Case Report ◽

Foreign Body ◽

Clinical Picture ◽

Foreign Body Aspiration ◽

Effective Therapy ◽

Partial Loss ◽

Detailed History ◽

Therapy Approach ◽

Diagnostic Confusion ◽

Respiratory Pathology

The authors present the case of a 4-year-old child admitted to the ENT Department with possible pulmonary foreign body aspiration. A detailed history revealed a clinical picture that seemed to depict an absence episode (with partial loss of conscience and cianosis) occured when eating, less the symptomes of a respiratory foreign body. Diagnosis needed full respiratory endoscopy and neurologic evaluation for correct assesment and effective therapy approach.

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Topical Tofacitinib: A Janus Kinase Inhibitor for the Treatment of Vitiligo in an Adolescent Patient

Case Reports in Dermatology ◽

10.1159/000513938 ◽

2021 ◽

pp. 190-194

Author(s):

Sineida Berbert Ferreira ◽

Rachel Berbert Ferreira ◽

Afonso Cesar Neves Neto ◽

Silvana Martins Caparroz Assef ◽

Morton Scheinberg

Keyword(s):

Case Report ◽

Skin Disease ◽

Kinase Inhibitor ◽

Effective Therapy ◽

Janus Kinase ◽

Jak Inhibitor ◽

Adolescent Patient ◽

Jak Inhibitors ◽

Janus Kinase Inhibitor ◽

History Of

Vitiligo is an autoimmune skin disease presenting with areas of depigmentation. Recent reports suggest that Janus kinase (JAK) inhibitors may be an effective therapy. In this case report, we show our experience with an adolescent patient with a long history of generalized and refractory vitiligo, for which treatment with topical tofacitinib, a JAK inhibitor, associated with phototherapy for 9 months, resulted in near complete repigmentation.

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