scholarly journals Malignant Peripheral Nerve Sheath Tumor of the Cervical Spine Treated with Surgical Resection Followed by X-ray Radiotherapy or Carbon Ion Radiotherapy: A Report of Three Cases

2020 ◽  
Vol 4 (3) ◽  
pp. 269-273
Author(s):  
Akira Honda ◽  
Yoichi Iizuka ◽  
Masahiko Okamoto ◽  
Shintaro Shiba ◽  
Hiromi Koshi ◽  
...  
2016 ◽  
Vol 21 (2) ◽  
pp. 250-254
Author(s):  
Kenichi Asano ◽  
Go Yoshida ◽  
Daigo Morita ◽  
Tadashi Ito ◽  
Yoji Shido ◽  
...  

2012 ◽  
Vol 52 (9) ◽  
pp. 670-674 ◽  
Author(s):  
Toru SASAMORI ◽  
Kazutoshi HIDA ◽  
Shunsuke YANO ◽  
Takeshi AOYAMA ◽  
Takeshi ASANO ◽  
...  

Spine ◽  
2008 ◽  
Vol 33 (19) ◽  
pp. E712-E716 ◽  
Author(s):  
Sung-Jun Moon ◽  
Jung-Kil Lee ◽  
Bo-Ra Seo ◽  
Jae-Hyoo Kim ◽  
Soo-Han Kim ◽  
...  

2013 ◽  
Vol 74 (11) ◽  
pp. 3140-3144 ◽  
Author(s):  
Yangi MUN ◽  
Hideyuki YOSHITOMI ◽  
Hidehiko UNO ◽  
Masayuki OTSUKA ◽  
Hiroaki SHIMIZU ◽  
...  

2016 ◽  
Vol 78 (5) ◽  
pp. 516-521
Author(s):  
Fumihisa SAWADA ◽  
Eiichi MAKINO ◽  
Takenobu YAMAMOTO ◽  
Ryo TANAKA ◽  
Yutaka FUJIWARA ◽  
...  

2021 ◽  
Author(s):  
Lucas F. Abrahao‐Machado ◽  
Carlos E. Bacchi ◽  
Cristielle P. Freitas ◽  
Jason L. Hornick

2020 ◽  
Vol 22 (Supplement_3) ◽  
pp. iii446-iii446
Author(s):  
Lacey Carter ◽  
Naina Gross ◽  
Rene McNall-Knapp ◽  
,and Jo Elle Peterson

Abstract At one month of age, a female presented with a giant congenital nevus along lower back and thighs and hydrocephalus. A ventriculoperitoneal shunt was placed. An MRI was done at six months, initially reported as normal. At eleven months of age, five months after original MRI, patient presented with dysconjugate gaze and lethargy. MRI showed new 3.8 x 3.7 x 3.4 cm right cerebellopontine angle mass extending into Meckel’s cave and foramen ovale along with leptomeningeal disease extending from the mass along the entire length of the spinal cord. Retrospective review of prior MRI revealed subtle leptomeningeal enhancement concerning for neurocutaneous melanosis (NCM). Given the leptomeningeal disease, family elected for open biopsy and debulking of lesion instead of aggressive resection. Histologically, the mass showed hypercellular spindle cell neoplasm with mitotic activity and necrosis mixed with remnants of normal cranial nerve. GFAP was negative, excluding a glioma. HMB-45, MITF, panmelanoma, and Melan-A were negative, excluding melanoma. A negative myogenin stain ruled out ectomesenchymoma. S-100 protein and SOX-10 positivity with variable loss of staining for trimethylation of histone H3 K27 were indicative of malignant peripheral nerve sheath tumor (MPNST). Given the course of the mass, trigeminal nerve MPNST was presumed. Given the poor prognosis of intracranial MPNST and NCM, family elected to forgo treatment and was discharged with hospice. She died 25 days after surgery. Cranial nerve MPNST is rare. MPNST in patients with NCM has not previously been reported to our knowledge.


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