Increase of constant weight rates of weighing bottles and evaporating dishes in a pharmacological experiment

2021 ◽  
Vol 25 (6 Part A) ◽  
pp. 4117-4125
Author(s):  
Qun Chen ◽  
Chenyu Zhao ◽  
Chengbing Tan ◽  
Ahmed Arbad
Keyword(s):  
Quality Control ◽  
Auxiliary Equipment ◽  
Constant Weight ◽  
Drug Quality ◽  
Drug Quality Control

Improving the constant weight rates of weighing bottles and evaporation dishes is beneficial to drug quality control. When different quantities of weighing bottles were dried under the same conditions, the greater the quantity is, the lower the constant weight rate will be. When quantities are controlled to be the same, weighing bottles that have been cooled for 50 minutes have higher constant weight rates than those cooled for half an hour. Without being affected by other factors, weighing bottles? constant weight rates are higher when the bottles are dried at the temperature of 180?C than 105?C. The rate increases when the bottled are dried for 8 hours instead of 5 hours. After soaking for 48 hours in the solution of 2% HNO3 + 6% HCl, the weighing bottles and evaporating dishes gain higher constant weight rates. Being more efficient, faster, economical and practical, this experiment has improved the method to increase constant weight rates of weighing bottles and evaporating dishes, without the need of auxiliary equipment, and thus increased the accuracy of drug weighing results.

scholarly journals New Approachs in Drug Quality Control: Matrices and Chemometrics

10.5772/50825 ◽  
2012 ◽  
Author(s):  
Sigrid Mennickent ◽  
M. de ◽  
B. Schulz ◽  
M. Vega ◽  
C. G.
Keyword(s):  
Quality Control ◽  
Drug Quality ◽  
Drug Quality Control

scholarly journals A Journey through the History of Drug Quality Control, from Greece to Costa Rica

2021 ◽  
Vol 9 (1) ◽  
pp. 33-47
Author(s):  
Jeimy Blanco Barrantes ◽  
María Soledad Quesada ◽  
Gustavo Rojas ◽  
Arlene Loría
Keyword(s):  
Quality Control ◽  
Costa Rica ◽  
The United States ◽  
Drug Analysis ◽  
Drug Quality ◽  
Evolution And Development ◽  
History Of ◽  
Pharmacy Quality ◽  
The University ◽  
Drug Quality Control

This review describes the evolution and development of drug quality control throughout different times in history. A bibliographic research was conducted from the database JSTOR from the University of Costa Rica. This database contains information from academic journals and books from XIX to date. It covers different fields, such as anthropology, arts, biology, botany, health sciences, politics, pharmacy, history. Information was retrieved when the following words were present: pharmacy, quality, quality control, drugs, medicines, pharmacopoeia. In ancient history India, China, Greece, Egypt, Africa and America used different medicinal plants to cure or alleviate disease. In some of these regions, methods were developed to make medicinal preparations as safe and effective as possible. In ancient Greece, the need to have a complete knowledge of drugs to carry out their proper preparation and detect adulterations was emerging. In Europe there was a constant development in the field, from books containing simple lists of preparations and medicines to more complex pharmacopoeias that included quality of the medicines. In America, the United States Pharmacopoeia (USP) first appeared in 1820. In Costa Rica, the Specialized Laboratory for Drug Analysis, actually the Laboratory for Analysis and Pharmaceutical Consulting (LAYAFA), was created in 1965, to ensure the quality and safety of medicines registered and marketed in Costa Rica. Differences between regulations and quality standards across centuries and countries, and their impact on the commercialization of medicines, have promoted regulations to harmonize the requirements related to different activities of the processes of manufacture, registration and quality control of medicines.

A STUDY ON THE QUALITY DECREASE OF AMOXICILLIN, ASPIRIN PH8 AND VITAMIN C DRUGS BY TIME UNDER THE EFFECTS OF TEMPERATURE AND HUMIDITY AT DIFFERENT AREAS IN HUE PROVINCE

2011 ◽  
pp. 104-110
Author(s):  
Huu Dung Tran ◽  
Quynh Phuong Nguyen ◽  
Thi Hong Phuc Huynh ◽  
Huu Tien Nguyen
Keyword(s):  
Quality Control ◽  
Vitamin C ◽  
Experimental Period ◽  
Mountainous Region ◽  
Drug Quality ◽  
Temperature And Humidity ◽  
Control Centre ◽  
Preliminary Research ◽  
Effects Of Temperature ◽  
Drug Quality Control

Background: A preliminary research about the relation of drug quality decrease through period of stored time by temperature and humidity at different geographic areas was carried on Aspirin pH8 intestine-disolved coated tablets, Vitamin C film coated tablets and Amoxcycillin capsules. Materials and method: Pharmaceuticals possessing same manufacture batch and date expire longer than experimental period preserved at Thuan An coastal area, Nam Dong mountainous region, flat country of Hue Province and Hue Drug Quality Control Centre, Vietnam. The change of temperature and humidity at drug stored pharmacies was recorded contineuosly. Monthly, these drugs were examed quality following Standards of Vietnam Pharmacopie Volumn III, edition 2002 and in-home Standards. Results: The decrease of drug quality happened earliest and strongest at Than An, then Nam Dong, sustained a severe elimate condition yearly. Especially, effect of humidity element on the drug decomposition was serious than temperature. The decrease of drug quality was also happened at Hue city but in gentle degree, while all drugs were still in good quality under the standard store condition at Drug Quality Control Centre (25oC, 60%). Conclusion: This research showed an importance of the temperature and humidity control during the store and delivery periods to maintain the drug quality sufficiently for treatment. Key words: drug quality, stored time, geographic areas, temperature, humidity

The problem of a unified approach to certifying standard samples for drug quality control

2021 ◽  
Vol 70 (8) ◽  
pp. 5-11
Author(s):  
A.A. Zhigalina ◽  
O.Yu. Strelova ◽  
N.I. Kotova ◽  
A.Yu. Malakhova ◽  
E.A. Tsekhanskaya
Keyword(s):  
Quality Control ◽  
Unified Approach ◽  
Standard Samples ◽  
Drug Quality ◽  
Drug Quality Control

scholarly journals HPLC Analysis of Orlistat and Its Application to Drug Quality Control Studies

2007 ◽  
Vol 55 (2) ◽  
pp. 251-254 ◽  
Author(s):  
Effat Souri ◽  
Hassan Jalalizadeh ◽  
Abbas Kebriaee-Zadeh ◽  
Bettina Zadehvakili
Keyword(s):  
Quality Control ◽  
Hplc Analysis ◽  
Drug Quality ◽  
Drug Quality Control
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