scholarly journals Ménétrier's disease associated with ulcerative collitis

2003 ◽  
Vol 60 (6) ◽  
pp. 747-751 ◽  
Author(s):  
Darko Mirkovic ◽  
Radoje Doder ◽  
Srbislav Ilic ◽  
Miroslav Mitrovic ◽  
Mile Ignjatovic

In this paper a 21 year old patient was presented with M?n?trier's disease, associated with ulcerative colitis. The first symptoms of ulcerative colitis occured at the age of eleven, since when the patient has been conservatively treated several times because of the exacerbations of the desease. During control examinations presence of polipoid changes in stomach was discovered by upper endoscopy. Gastrectomy was suggested because the patient had excessive anemic syndrome which required weekly substitutional therapy with deplasmatic eritrocytes, as well as hypoproteinemia, while multiple polipoid changes suspect for malignancy were gastroscopically identifided. Patient accepted surgical treatment, and was transfered to the Clinic of Surgery. Total gastrectomy was performed, and patohystological finding confirmed M?n?trier's desease. After two weeks, the patient was released from the hospital in good general condition, with regular clinical and laboratory findings.

1960 ◽  
Vol 39 (3) ◽  
pp. 347-350 ◽  
Author(s):  
Earl E. Gambill ◽  
Donald C. Campbell ◽  
Donald C. Balfour ◽  
John M. Waugh ◽  
Malcolm B. Dockerty

2021 ◽  
Vol 14 (10) ◽  
pp. e246137
Author(s):  
Sofia Rao ◽  
Anna Viola ◽  
Omar Ksissa ◽  
Walter Fries

Ménétrier’s disease (MD) is a rare disease of the stomach, characterised by hypertrophic gastric folds leading to protein loss. The association with ulcerative colitis (UC) is rare but has been reported in the literature. We report a case of a 29-year-old male affected by UC with an additional diagnosis of MD 3 years after UC diagnosis. UC was refractory to several treatment lines (thiopurines, infliximab, vedolizumab and ustekinumab), and the patient underwent colectomy. Octreotide was administered for MD normalising blood biochemistry, but it was not effective in inducing endoscopic remission of the stomach. Treatment options in patients with MD and UC are discussed.


Gut ◽  
2011 ◽  
Vol 60 (11) ◽  
pp. 1607-1608 ◽  
Author(s):  
K.-P. Zimmer ◽  
M. Heine ◽  
G. Weissen-Plenz ◽  
K. A. Scholand ◽  
H. Herbst ◽  
...  

2008 ◽  
Vol 40 (1) ◽  
pp. 78-79 ◽  
Author(s):  
I. Hatemi ◽  
E. Caglar ◽  
D. Aksoy ◽  
S. Goksel ◽  
A. Dobrucali

1950 ◽  
Vol 16 (4) ◽  
pp. 773-781 ◽  
Author(s):  
Donald C. Balfour ◽  
Nicholas C. Hightower ◽  
Earl E. Gambill ◽  
John M. Waugh ◽  
Malcolm B. Dockerty

2021 ◽  
Vol 8 (1) ◽  
pp. e000806
Author(s):  
Tahrima Kayes ◽  
Mark Bonnichsen ◽  
Laura Willmann ◽  
Aldenb Lorenzo ◽  
Amitabha Das ◽  
...  

Ménétrier’s disease (MD) is a rare gastropathy characterised by giant rugal folds which can present with nausea, vomiting, abdominal pain and protein losing gastropathy. We report a 21-year-old woman with comorbid MD and ulcerative colitis (UC). Management was complicated by limited treatment options for MD, significant symptom burden, worsening nutrition and difficulty determining which disease was the predominant cause of symptoms. Since age 18 the patient experienced recurrent UC flares characterised by diarrhoea, persistent vomiting and corticosteroid dependence. Endoscopic assessment demonstrated concurrent MD and active UC. Octreotide and cetuximab were trialled given persistent hypoalbuminaemia and suspicion for MD associated protein-losing gastropathy. UC management comprised dose-optimised infliximab and methotrexate. Repeat endoscopic assessment demonstrated improvement in UC without corresponding improvement in symptoms or hypoalbuminaemia. Nasojejunal feeding and parenteral nutrition failed to significantly improve nutritional status and accordingly the patient proceeded to radical total gastrectomy. Postoperatively, MD-associated symptoms and hypoalbuminemia resolved completely.


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