Manx Shearwater Chicks: Seasonal, Parental, and Genetic Influences on the Chick's Age and Weight at Fledging

The Condor ◽  
1986 ◽  
Vol 88 (3) ◽  
pp. 324-327 ◽  
Keyword(s):  
Genetic Influences ◽  
Manx Shearwater

Ultrastructure of Cryptorchidism and Seminoma

1981 ◽  
Vol 39 ◽  
pp. 540-541
Author(s):  
Shirley Siew ◽  
Susan C. James
Keyword(s):  
Malignant Tumors ◽  
Frozen Section ◽  
Malignant Potential ◽  
Genetic Influences ◽  
Endocrine Gland ◽  
Medial Aspect ◽  
Left Testis ◽  
Bilateral Orchiectomy

Testicular maldescent is the most common endocrine gland abnormality, as 2.7% of mature neonates are cryptorchid. The significant complications are that there is a disturbance of normal maturation which results in diminished fertility and there is an increase in the malignant potential which is 35 times greater in the undescended than the descended testis. It is considered that genetic influences may be of etiological importance and recurrence has been described in some families. It is of interest, that the case reported here has 2 siblings who have also presented with cryptorchidism and malignant tumors.The propositus is 14 years old. He is well developed (described by some as obese) and shows normal secondary male characteristics except for an immature scrotum. Laparotomy showed both testes to be intraabdominal. A hard nodule (0.5cm) was palpated on the medial aspect of the left testis. Frozen section showed the presence of seminoma and bilateral orchiectomy was performed.

Combined genetic influences on episodic memory decline in older adults without dementia.

2020 ◽  
Vol 34 (6) ◽  
pp. 654-666 ◽  
Author(s):  
Erika J. Laukka ◽  
Ylva Köhncke ◽  
Goran Papenberg ◽  
Laura Fratiglioni ◽  
Lars Bäckman
Keyword(s):  
Older Adults ◽  
Episodic Memory ◽  
Genetic Influences ◽  
Memory Decline

Genetic influences on the induction of eosinophilic pathology during lung viral infection

1997 ◽  
Vol 56 (1-3) ◽  
pp. 305-306 ◽  
Author(s):  
T Hussell
Keyword(s):  
Viral Infection ◽  
Genetic Influences

Polygenic Risk Score for Smoking is associated with Externalizing Psychopathology and Disinhibited Personality Traits but not Internalizing Psychopathology in Adolescence

2020 ◽  
Author(s):  
Brian M. Hicks ◽  
D. Angus Clark ◽  
Joseph D. Deak ◽  
Mengzhen Liu ◽  
C. Emily Durbin ◽  
...  
Keyword(s):  
Personality Traits ◽  
Genetic Risk ◽  
Behavioral Control ◽  
Cumulative Exposure ◽  
Genetic Influences ◽  
Behavioral Disinhibition ◽  
Polygenic Risk ◽  
Externalizing Psychopathology ◽  
Internalizing Psychopathology ◽  
Random Intercept

Importance: Large consortia of genome wide association studies have yielded more accurate polygenic risk scores (PRS) that aggregate the small effects of many genetic variants to characterize the genetic architecture of disorders and provide a personalized measure of genetic risk. Objective: We examined whether a PRS for smoking measured genetic risk for general behavioral disinhibition by estimating its associations with externalizing and internalizing psychopathology and related personality traits. We examined these associations at multiple time points in adolescence using more refined phenotypes defined by stable characteristics across time and at young ages, which reduced potential confounds associated with cumulative exposure to substances and reverse causality. Methods: Random intercept panel models were fit to symptoms of conduct disorder, oppositional defiant disorder, major depressive disorder (MDD), and teacher ratings of externalizing and internalizing problems and personality traits at ages 11, 14, and 17 years-old in the Minnesota Twin Family Study (N = 3225). Results: The smoking PRS had strong associations with the random intercept factors for all the externalizing measures (mean standardized ꞵ = .27), agreeableness (ꞵ=-.22, 95% CI: -.28, -.16), and conscientiousness (ꞵ=-.19, 95% CI: -.24, -.13), but was not significantly associated with the internalizing measures (mean ꞵ = .06) or extraversion (ꞵ=.01, 95% CI: -.05, .07). After controlling for smoking at age 17, the associations with the externalizing measures (mean ꞵ = .13) and personality traits related to behavioral control (mean ꞵ = -.10) remained statistically significant. Conclusions and Relevance: The smoking PRS measures genetic influences that contribute to a spectrum of phenotypes related to behavioral disinhibition including externalizing psychopathology and normal-range personality traits related to behavioral control, but not internalizing psychopathology. Continuing to identify the correlates and delineate the mechanisms of the genetic influences associated with disinhibition could have substantial impact in mitigating a variety of public health problems (e.g., mental health, academic achievement, criminality).

Genetic Influences in Cannabis Use Disorder and Psychosis: Dopamine and Beyond

2017 ◽  
Vol 22 (42) ◽  
pp. 6392-6396 ◽  
Author(s):  
Amine Benyamina ◽  
Laurent Karila ◽  
Geneviève Lafaye ◽  
Lisa Blecha
Keyword(s):  
Cannabis Use ◽  
Genetic Influences ◽  
Cannabis Use Disorder

Genetic Influences on Maternal Care

2002 ◽  
Vol 160 (6) ◽  
pp. S173
Author(s):  
Peripato ◽  
Cheverud
Keyword(s):  
Maternal Care ◽  
Genetic Influences
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