Susceptibility to Eimeria tenella of Chickens and Chicken Embryos of Partly Inbred Lines Possessing Homozygous Major Histocompatibility Complex Haplotypes

1993 ◽  
Vol 37 (4) ◽  
pp. 1113 ◽  
Author(s):  
Yutaka Nakai ◽  
Koji Edamura ◽  
Kazunori Kanazawa ◽  
Shinya Shimizu ◽  
Yoshikazu Hirota ◽  
...  
Keyword(s):  
Major Histocompatibility Complex ◽  
Inbred Lines ◽  
Eimeria Tenella ◽  
Major Histocompatibility ◽  
Chicken Embryos ◽  
Histocompatibility Complex

scholarly journals Association of serum hemolytic complement levels with the major histocompatibility complex in chickens.

1976 ◽  
Vol 144 (2) ◽  
pp. 555-561 ◽  
Author(s):  
T C Chanh ◽  
A A Benedict ◽  
H Abplanalp
Keyword(s):  
Major Histocompatibility Complex ◽  
Inbred Line ◽  
Dominant Gene ◽  
Inbred Lines ◽  
Immune Responsiveness ◽  
Mixed Leukocyte Reaction ◽  
Major Histocompatibility ◽  
Histocompatibility Complex ◽  
The Relationship

The total hemolytic complement (C) levels in inbred line 7 chicks and adults were lower than C levels in inbred lines 2 and 3 and in outbred chickens of the same age. In all birds, adult levels of C were obtained in 5- to 6-wk-old chickens. Analysis of F1 and F3 generations clearly showed that the C level in chickens was determined by a dominant gene(s) associated with the major histocompatibility complex. Finding this association in a nonmammal strengthens the importance of the relationship between closely linked genes controlling histocompatibility, immune responsiveness, mixed leukocyte reaction, and C activity.

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