316 QUANTIFICATION OF PATHOGENIC LEPTOSPIRA IN SURFACE WATERS EXPLAINS URBAN PREDOMINANCE OF SEVERE HUMAN LEPTOSPIROSIS IN THE PERUVIAN AMAZON.

2006 ◽  
Vol 54 (1) ◽  
pp. S134.3-S134
Author(s):  
C. A. Ganoza ◽  
J. M. Vinetz
Keyword(s):  
Surface Waters ◽  
Peruvian Amazon ◽  
Pathogenic Leptospira ◽  
Human Leptospirosis

scholarly journals Spatial and temporal dynamics of pathogenic Leptospira in surface waters from the urban slum environment

2018 ◽  
Vol 130 ◽  
pp. 176-184 ◽  
Author(s):  
Arnau Casanovas-Massana ◽  
Federico Costa ◽  
Irina N. Riediger ◽  
Marcelo Cunha ◽  
Daiana de Oliveira ◽  
...  
Keyword(s):  
Surface Waters ◽  
Temporal Dynamics ◽  
Urban Slum ◽  
Pathogenic Leptospira ◽  
Spatial And Temporal Dynamics

scholarly journals Distribution and Diversity of Pathogenic Leptospira Species in Peri-domestic Surface Waters from South Central Chile

2016 ◽  
Vol 10 (8) ◽  
pp. e0004895 ◽  
Author(s):  
Meghan R. Mason ◽  
Carolina Encina ◽  
Srinand Sreevatsan ◽  
Claudia Muñoz-Zanzi
Keyword(s):  
Surface Waters ◽  
Pathogenic Leptospira ◽  
Central Chile ◽  
South Central ◽  
Leptospira Species

scholarly journals Isolation of pathogenic Leptospira strains from naturally infected cattle in Uruguay reveals high serovar diversity, and uncovers a relevant risk for human leptospirosis

2018 ◽  
Vol 12 (9) ◽  
pp. e0006694 ◽  
Author(s):  
Leticia Zarantonelli ◽  
Alejandra Suanes ◽  
Paulina Meny ◽  
Florencia Buroni ◽  
Cecilia Nieves ◽  
...  
Keyword(s):  
Infected Cattle ◽  
Pathogenic Leptospira ◽  
Human Leptospirosis

scholarly journals Human Leptospirosis Caused by a New, Antigenically Unique Leptospira Associated with a Rattus Species Reservoir in the Peruvian Amazon

2008 ◽  
Vol 2 (4) ◽  
pp. e213 ◽  
Author(s):  
Michael A. Matthias ◽  
Jessica N. Ricaldi ◽  
Manuel Cespedes ◽  
M. Monica Diaz ◽  
Renee L. Galloway ◽  
...  
Keyword(s):  
Peruvian Amazon ◽  
Human Leptospirosis

scholarly journals Fifteen years of human leptospirosis in São Paulo, Brazil

2015 ◽  
Vol 2 (1) ◽  
pp. 56 ◽  
Author(s):  
Roberta M. Blanco ◽  
Eliete C. Romero
Keyword(s):  
Public Health ◽  
Age Groups ◽  
Sao Paulo ◽  
São Paulo ◽  
Serum Samples ◽  
Public Health Importance ◽  
Pathogenic Leptospira ◽  
Human Leptospirosis ◽  
Leptospira Spp ◽  
Seasonal Analysis

Objective: Leptospirosis is a worldwide zoonosis caused by pathogenic Leptospira spp. The aim of this study was to report theincidence of leptospirosis from 1998 to 2012 in the state of São Paulo, Brazil to show the importance of human leptospirosis andto describe some epidemiological characteristics.Methods: From January 1998 to December 2012, sera from patients with suspected leptospirosis were analyzed. The microscopicagglutination test (MAT) was used for serological investigations and MLST, serotyping and PFGE methods for the identificationof leptospires. The descriptive seasonal analysis was performed with Excel Microsoft version 2007. Pearson’s correlation wasused to assess the association between rainfall and the number of cases.Results: Among 22,795 serum samples, 2,430 cases of leptospirosis were laboratory confirmed, giving an average incidence rateof 1.35/100,000 inhabitants. Of these patients, 2,032 (83.62%) were male with a predominance in the age groups of 21-50 years.The highest incidence and rainfall were from December to April. There was correlation between the rainfall and the number ofcases. Icterohaemorrhagiae was the predominant serogroup.Conclusions: This study shows that leptospirosis is a seasonal disease in São Paulo with most cases occurring during the rainyseason, and thus, will continue to be a disease of public health importance. 

scholarly journals Determining Risk for Severe Leptospirosis by Molecular Analysis of Environmental Surface Waters for Pathogenic Leptospira

PLoS Medicine ◽  
2006 ◽  
Vol 3 (8) ◽  
pp. e308 ◽  
Author(s):  
Christian A Ganoza ◽  
Michael A Matthias ◽  
Devon Collins-Richards ◽  
Kimberly C Brouwer ◽  
Calaveras B Cunningham ◽  
...  
Keyword(s):  
Molecular Analysis ◽  
Surface Waters ◽  
Pathogenic Leptospira ◽  
Environmental Surface ◽  
Severe Leptospirosis

Detection of pathogenic Leptospira spp. infections among mammals captured in the Peruvian Amazon basin region.

2000 ◽  
Vol 63 (5) ◽  
pp. 255-258 ◽  
Author(s):  
J E Bunnell ◽  
C L Hice ◽  
V Montrueil ◽  
D M Watts ◽  
J M Vinetz ◽  
...  
Keyword(s):  
Amazon Basin ◽  
Peruvian Amazon ◽  
Pathogenic Leptospira ◽  
Leptospira Spp ◽  
Basin Region

scholarly journals Molecular characterization of pathogenic Leptospira sp. in small mammals captured from the human leptospirosis suspected areas of Selangor state, Malaysia

Acta Tropica ◽  
2018 ◽  
Vol 188 ◽  
pp. 68-77 ◽  
Author(s):  
Nurul Natasya Azhari ◽  
Siti Nur Alia Ramli ◽  
Narcisse Joseph ◽  
Noraini Philip ◽  
Nooreen Farzana Mustapha ◽  
...  
Keyword(s):  
Molecular Characterization ◽  
Small Mammals ◽  
Pathogenic Leptospira ◽  
Human Leptospirosis

scholarly journals Tracking animal reservoirs of pathogenic Leptospira: the right test for the right claim.

2021 ◽  
Author(s):  
Yann Gomard ◽  
Koussay Mohamed Dellagi ◽  
Steven Goodman ◽  
Patrick Mavingui ◽  
Pablo Tortosa
Keyword(s):  
Chronic Infection ◽  
One Health ◽  
Molecular Detection ◽  
Published Data ◽  
Pathogenic Leptospira ◽  
Human Leptospirosis ◽  
Previous Infection ◽  
Serological Data ◽  
The Right ◽  
Animal Reservoirs

Leptospirosis, caused by a pathogenic Leptospira bacteria, is the most prevalent zoonosis worldwide and in this context has been extensively investigated through a One Health framework. Diagnosis of human leptospirosis includes molecular and serological tools, with serological Microscopic Agglutination Test (MAT) still being considered as a gold standard. Mammals considered as biological reservoirs include species or populations that are able to maintain chronic infection and shed the bacteria via their urine in the environment. Leptospira bacteria are often investigated using the same diagnosis tool, serological MAT. However, MAT testing of putative animal reservoirs can lead to mis-interpretations as it can signal previous infection and not necessarily bring in robust information regarding the capacity of such sero-positive animals to maintain chronic infection. We use previously published data and present new results on introduced and endemic small mammals to show that MAT should not be used for the identification of reservoirs. By contrast, serological data are informative on the level of exposure of animals occupying a specific environment. Finally, we present a sequential methodology to investigate human leptospirosis in a One Health framework that associates molecular detection in humans and animals, together with MAT of human samples using Leptospira isolates obtained from reservoir animals occurring in the same environment.

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