Mechanism of Action of Cherry Bark-containing Jumihaidokuto (Shi-Wei-Bai-Du-Tang) and Its Clinical Benefit in Patients with Acne Vulgaris

2014 ◽  
Vol 76 (2) ◽  
pp. 140-146
Author(s):  
Tsukasa TAKEMURA ◽  
Hiromi TOHNO ◽  
Satoshi YOMODA ◽  
Toshiki OKUBO
2018 ◽  
Vol 21 (4) ◽  
Author(s):  
Paula Dębek ◽  
Anna Piotrowska ◽  
Magdalena Nastałek ◽  
Natalia Totko-Borkusiewicz ◽  
Olga Czerwińska-Ledwig ◽  
...  

Introduction. Dermatoses, such as acne vulgaris, acne rosacea and hyperpigmentations, are an increasingly common problem, their chronic character affecting the quality of life of the affected people. One of the substances with a multidirectional mechanism of action and a wide spectrum of applications is azelaic acid. Aim. The aim of this paper was to present azelaic acid as a substance suitable for treatment of many skin problems. Material and methods. The authors have analyzed the literature from 1986-2018, looking for works indicating the mechanism, effectiveness and safety of azelaic acid treatment in selected diseases. Results. This ingredient proved to meet the high requirements. Conclusions. Systematic use of azelaic acid reduces acne lesions, lightens discolorations and eliminates most of the symptoms of rosacea. It is used alone or in polytherapy, however combined therapies require further clinical trials indicating the directionality of such treatment.


2004 ◽  
Vol 151 (3) ◽  
pp. 616-622 ◽  
Author(s):  
B. Pollock ◽  
D. Turner ◽  
M.R. Stringer ◽  
R.A. Bojar ◽  
V. Goulden ◽  
...  

1974 ◽  
Vol 1 (5) ◽  
pp. 191-200 ◽  
Author(s):  
James E. Fulton ◽  
A. Farzad-Bakshandeh ◽  
Sara Bradley

2007 ◽  
Vol 87 (4) ◽  
pp. 325-329 ◽  
Author(s):  
C Hörfelt ◽  
B Stenquist ◽  
O Larkö ◽  
J Faergemann ◽  
AM Wennberg

1997 ◽  
Vol 22 (5) ◽  
pp. 211-215 ◽  
Author(s):  
S. SOMMKR ◽  
R. BOJAR ◽  
WJ. CUNLIFFE ◽  
D. HOLLAND ◽  
K.T. HOLLAND ◽  
...  

Author(s):  
Ahmed Samei Huda

Criticisms of psychiatric treatment often involve comparison to idealized depictions of general medical treatment. Psychiatric treatments are described as not reversing diseases but many treatments in general medicine also do not reverse disease and some have unknown mechanisms. It is stated that psychiatrists prescribe medication to reverse hypothesized mechanisms, but a survey found they usually prescribed a medication in a clinical situation because research had shown it to be effective, even though the mechanism of action was unclear. Antidepressants are said to be ineffective because of a small overall effect averaged over groups of participants but this ignores evidence that some people will derive a significant clinical benefit. Antipsychotics are effective in preventing relapse of psychosis in research studies; for a variety of reasons, withdrawal-induced psychosis is unlikely to explain enough of this advantage to prove the claim that antipsychotics are ineffective. Although lithium research trials are imperfect, including reporting high rates of lithium withdrawal-induced mania, there is still some evidence of benefit in acute mania and of modest benefit in preventing relapse of bipolar disorder in those who can continue lithium for two years or more. Questions comparing psychiatric and general medical treatments were generated.


1997 ◽  
Vol 22 (05) ◽  
pp. 211-215 ◽  
Author(s):  
S. SOMMER ◽  
R. BOJAR ◽  
W.J. CUNLIFFE ◽  
D. HOLLAND ◽  
K.T. HOLLAND ◽  
...  

2006 ◽  
Vol 155 (4) ◽  
pp. 748-755 ◽  
Author(s):  
E.D. Seaton ◽  
P.E. Mouser ◽  
A. Charakida ◽  
S. Alam ◽  
P.E. Seldon ◽  
...  

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