A Case of Crohn's Disease Diagnosed from a Subcutaneous Abscess Caused by Enterocutaneous Fistula

2015 ◽  
Vol 77 (2) ◽  
pp. 128-130
Author(s):  
Toshikazu OMODAKA ◽  
Koichi HAYASHI ◽  
Fuminao KAMIJO ◽  
Atsuko OHASHI ◽  
Tomomi MIYAKE ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Enterocutaneous Fistula

T1305 Are Anti-TNFS Able to Close Enterocutaneous Fistula in Crohn's Disease?

2010 ◽  
Vol 138 (5) ◽  
pp. S-533
Author(s):  
Setakhr Vida ◽  
Philippe Seksik ◽  
Treton Xavier ◽  
Matthieu Allez ◽  
Martine De Vos ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Enterocutaneous Fistula

Enterocutaneous fistula in severely active Crohn’s disease: preoperative anti-TNF alpha treatment to limit bowel resection—report of a case

2018 ◽  
Vol 34 (2) ◽  
pp. 369-373 ◽  
Author(s):  
Peter Wilhelm ◽  
Andreas Kirschniak ◽  
Jonas Johannink ◽  
Sascha Kaufmann ◽  
Thomas Klag ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Bowel Resection ◽  
Enterocutaneous Fistula ◽  
Tnf Alpha

scholarly journals Effect of Adalimumab on an Enterocutaneous Fistula in Patients with Crohn's Disease: A Case Series

2015 ◽  
Vol 54 (20) ◽  
pp. 2603-2607 ◽  
Author(s):  
Kaori Fujiwara ◽  
Takuya Inoue ◽  
Naoki Yorifuji ◽  
Munetaka Iguchi ◽  
Taisuke Sakanaka ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Enterocutaneous Fistula ◽  
Case Series

DOP32 Long-term outcomes of enterocutaneous fistula complicating Crohn’s Disease: The ECUFIT study from GETECCU

2021 ◽  
Vol 15 (Supplement_1) ◽  
pp. S070-S071
Author(s):  
I Rodríguez-Lago ◽  
C García Pérez ◽  
M Calafat ◽  
M P Soto ◽  
M Calvo ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Surgical Management ◽  
Medical Therapy ◽  
Enterocutaneous Fistula ◽  
Fistula Closure ◽  
Number Of Patients ◽  
Fistula Recurrence ◽  
History Of ◽  
Multivariable Regression

Abstract Background Crohn’s disease (CD) can develop fistulizing complications at any time during the disease course. Enterocutaneous fistulas (ECF) are disabling lesions with a significant impact on quality of life. The aim of this study was to describe the characteristics and natural history of ECF complicating CD, and to analyze its medical and/or surgical management. Methods A retrospective analysis of all adult patients with fistulizing CD with at least one episode of ECF from the ENEIDA registry (over 68,000 patients) was performed. ECF were defined as a communication between the gastrointestinal tract and the skin producing leakage of luminal contents. Additional data describing the ECF and its medical or surgical management were gathered. The main endpoint was any ECF-related surgical intervention. Fistula closure was defined as the absence of drainage, with no new abscess or surgery for at least 6 months. A comparison of the characteristics and outcomes after the availability of biologic agents (Jan/2000) was also performed. The baseline characteristics were analyzed by means of descriptive statistics and were compared by non-parametric tests. Factors associated with surgery were further evaluated in a binary multivariable regression and survival analysis. Results A total of 301 ECF in 286 patients from 46 hospitals diagnosed between Jan/1970-Sept/2020 were included (median age 34 years (IQR, 27–46); 59% male; 67% L3). ECF had a median of 1 external opening (range 1–10), 59% with concomitant internal fistulas, and usually involved the ileum (67%) or colon (23%). After 146 months (IQR, 69–233) of follow-up, 37% received thiopurines, 40% anti-TNF, 6% ustekinumab and 2% vedolizumab. Surgery was performed in 208 patients (69%) after a median of 4 months (IQR, 1.4–12). Fistula closure was achieved in 253 patients (84%) after 30 months (IQR, 4–84), mostly after surgery (54%) and in one third after medical therapy. Fistula recurrence was uncommon (11%) after closure. Patient and fistula characteristics were significantly different after the availability of biologics. In fact, anti-TNF biologics and thiopurines reduced surgery risk (HR 0.5; 0.38–0.67; HR 0.64; 0.47–0.86, respectively). The surgery rate in the biologic era tends to be lower than before (OR 0.63;0.33–1.09) while timing is similar. Closure rates are also comparable, but it was obtained more frequently after medical therapy once biologicals were available (OR 2.21; 1.13–4.29). Conclusion ECF complicating CD entail a high burden of medical and surgical resources. Closure rates are high, usually after surgery, and fistula recurrence is uncommon. A number of patients can benefit from medical therapy and achieve fistula closure.

scholarly journals Granulomatous (Crohn’s) Appendicitis

1991 ◽  
Vol 5 (3) ◽  
pp. 112-117
Author(s):  
Hanna Binder ◽  
Hugh J Freeman
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
High Frequency ◽  
Inflammatory Process ◽  
Recurrent Disease ◽  
Enterocutaneous Fistula ◽  
Symptomatic Recurrence ◽  
University Of British Columbia ◽  
The University ◽  
Gut Pathogens

Four patients with Crohn’s disease limited initially to the appendix, treated by appendectomy and seen at the University of British Columbia Hospital, Vancouver, during 1980-90 are described. In all patients the initial diagnosis was based on the presence of an appendiceal granulomatous inflammatory process, while other causes such as sarcoidosis, tuberculosis and bacterial gut pathogens were excluded. While post appendectomy complications, including enterocutaneous fistula, did not occur, symptomatic recurrence was later observed in three patients four to 24 months following appendiceal resection. This recurrence was associated with a diagnosis of recurrent Crohn’s disease and histological findings of granulomas elsewhere in the gastrointestinal tract. In conclusion, a ‘reagent grade’ population of patients with Crohn’s disease limited to the appendix was seen. A high frequency of recurrent disease was defined, indicating that isolated granulomarous appendicitis may be the initial and sole presenting feature of Crohn’s disease.

(029) Enterocutaneous fistula in Crohn’s disease

2009 ◽  
Vol 10 (2) ◽  
pp. AB20
Author(s):  
W. Badre ◽  
S. Alaoui Slimani ◽  
F. Haddad ◽  
M. Tahiri ◽  
A. Bellabah ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Enterocutaneous Fistula
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