1753-P: Insulin Sensitivity in Long-Lived Growth Hormone–Releasing Hormone Knockout Mice

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 1753-P ◽  
Author(s):  
FANG ZHANG ◽  
MERT ICYUZ ◽  
LIOU SUN
Keyword(s):  
Growth Hormone ◽  
Insulin Sensitivity ◽  
Knockout Mice ◽  
Growth Hormone Releasing Hormone ◽  
Releasing Hormone

scholarly journals Insulin sensitivity in long-lived growth hormone-releasing hormone knockout mice

Aging ◽  
2020 ◽  
Vol 12 (18) ◽  
pp. 18033-18051
Author(s):  
Fang Zhang ◽  
Mert Icyuz ◽  
Zhenghui Liu ◽  
Michael Fitch ◽  
Liou Y. Sun
Keyword(s):  
Growth Hormone ◽  
Insulin Sensitivity ◽  
Knockout Mice ◽  
Growth Hormone Releasing Hormone ◽  
Releasing Hormone

Behavioural phenotyping of male growth hormone-releasing hormone (GHRH) knockout mice

2014 ◽  
Vol 24 (5) ◽  
pp. 192-197 ◽  
Author(s):  
Sheila Leone ◽  
Rugia Shohreh ◽  
Fabio Manippa ◽  
Lucia Recinella ◽  
Claudio Ferrante ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Knockout Mice ◽  
Growth Hormone Releasing Hormone ◽  
Releasing Hormone ◽  
Behavioural Phenotyping

Increased pain and inflammatory sensitivity in growth hormone-releasing hormone (GHRH) knockout mice

2019 ◽  
Vol 144 ◽  
pp. 106362 ◽  
Author(s):  
Sheila Leone ◽  
Annalisa Chiavaroli ◽  
Lucia Recinella ◽  
Giustino Orlando ◽  
Claudio Ferrante ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Knockout Mice ◽  
Growth Hormone Releasing Hormone ◽  
Releasing Hormone

scholarly journals Effects of a Growth Hormone-Releasing Hormone Analog on Endogenous GH Pulsatility and Insulin Sensitivity in Healthy Men

2011 ◽  
Vol 96 (1) ◽  
pp. 150-158 ◽  
Author(s):  
Takara L. Stanley ◽  
Cindy Y. Chen ◽  
Karen L. Branch ◽  
Hideo Makimura ◽  
Steven K. Grinspoon
Keyword(s):  
Growth Hormone ◽  
Insulin Sensitivity ◽  
Growth Hormone Releasing Hormone ◽  
Healthy Men ◽  
Releasing Hormone ◽  
Hormone Analog

Extension of Maximum Lifespan in Growth Hormone-Releasing Hormone Knockout Mice

2011 ◽  
pp. P2-328-P2-328
Author(s):  
Adam Spong ◽  
Michal Masternak ◽  
Oge Arum ◽  
Roberto Salvatori ◽  
Andrzej Bartke
Keyword(s):  
Growth Hormone ◽  
Knockout Mice ◽  
Growth Hormone Releasing Hormone ◽  
Maximum Lifespan ◽  
Releasing Hormone

Association of pituitary adenoma with neuronal christoma: A TEM study

1994 ◽  
Vol 52 ◽  
pp. 232-233
Author(s):  
Eva Horvath ◽  
Kalman Kovacs ◽  
B. W. Scheithauer ◽  
R. V. Lloyd ◽  
H. S. Smyth
Keyword(s):  
Growth Hormone ◽  
Pituitary Adenoma ◽  
Pituitary Tumor ◽  
Nervous Tissue ◽  
Alternative Explanation ◽  
Growth Hormone Releasing Hormone ◽  
Cell Hyperplasia ◽  
Releasing Hormone ◽  
Secretory Neurons

The association of a pituitary adenoma with nervous tissue consisting of neuron-like cells and neuropil is a rare abnormality. In the majority of cases, the pituitary tumor is a chromophobic adenoma, accompanied by acromegaly. Histology reveals widely variable proportions of endocrine and nervous tissue in alternating or intermingled patterns. The lesion is perceived as a composite one consisting of two histogenetically distinct parts. It has been suggested that the neuronal component, morphologically similar to secretory neurons of the hypothalamus, may initiate adenoma formation by releasing stimulatory substances. Immunoreactivity for growth hormone releasing hormone (GRH) in the neuronal component of some cases supported this view, whereas other findings such as consistent lack of growth hormone (GH) cell hyperplasia in the lesions called for alternative explanation.Fifteen tumors consisting of a pituitary adenoma and a neuronal component have been collected over a 20 yr. period. Acromegaly was present in 11 patients, was equivocal in one, and absent in 3.

Treatment with growth hormone-releasing hormone (GHRH) 1-44 stimulates growth velocity in growth hormone-deficient children

1989 ◽  
Vol 120 (3_Suppl) ◽  
pp. S85-S86
Author(s):  
Y.-F. SHI ◽  
X.-L. BAO ◽  
R. Liu ◽  
J.-Y. DENG ◽  
W. REINHARDT ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Growth Velocity ◽  
Growth Hormone Releasing Hormone ◽  
Releasing Hormone
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