Photobiomodulation (PBM) is an accurate term for an effective and important application of light in medicine (such as in photomedicine). Three review articles of authors from the International Society of Medical Laser Applications (ISLA-Transcontinental) on the topic of PBM with a total of 116 printed pages, published in one renowned journal of molecular sciences with an impact factor of 13.668, are presented in the current review. The main topics are PBM, probiotics, curcumin, and arthritis. PBM can modulate cellular dysfunctions, trigger self-organization phenomena, and alleviate different diseases.