Noninvasive assessment of liver fibrosis in chronic hepatitis C virus patients compared to liver biopsy: the experience of tertiary level hospital in Serbia

2020 ◽  
Vol 111 (3) ◽  
Author(s):  
Tomislav Preveden ◽  
Benjamin Vereš ◽  
Maja Ružić ◽  
Maria Pete ◽  
Francesco Luzza ◽  
...  
2015 ◽  
Vol 156 (21) ◽  
pp. 855-861 ◽  
Author(s):  
Alajos Pár ◽  
Áron Vincze ◽  
Gabriella Pár

Chronic hepatitis C virus infection associated with necroinflammation predisposes to liver fibrosis and cirrhosis, which lead to severe end-stage complications. Staging of fibrosis is of basic importance for the indication of antiviral treatment, for monitoring the response and predicting the prognosis of patients with hepatitis C virus related liver disease. Since liver biopsy, the “gold standard” diagnosis of fibrosis is invasive and it has some other limitations, non-invasive methods have been developed and widely used in the clinical practice. Serum biomarkers and physical approaches measuring liver stiffness by elastography as well as combination algorithms have been gradually been integrated into guidelines resulting in a reduction of the need for liver biopsy. The authors review these non-invasive fibrosis markers and discuss their role in the indication of treatment, follow-up, and assessment of prognosis of patients with chronic hepatitis C virus infection. Orv. Hetil., 2015, 156(21), 855–861.


2008 ◽  
Vol 46 (4) ◽  
pp. 423-428 ◽  
Author(s):  
Kathleen B Schwarz ◽  
Aglaia Zellos ◽  
Lisette Stamato ◽  
John Boitnott ◽  
Elizabeth Perlman ◽  
...  

2020 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Maria Pokorska-Śpiewak ◽  
Anna Dobrzeniecka ◽  
Marta Lipińska ◽  
Anna Tomasik ◽  
Małgorzata Aniszewska ◽  
...  

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