A case of thyroid carcinoma with cervical and mediastinal lymph node metastases that required mediastinal lymph node dissection via median sternotomy

Chirurgia ◽  
2020 ◽  
Vol 33 (5) ◽  
Author(s):  
Junzo Shimizu ◽  
Makio Moriya ◽  
Tadashi Kamesui ◽  
Susumu Miyamoto ◽  
Toshiro Nagayoshi ◽  
...  
2019 ◽  
Vol 14 (10) ◽  
pp. S1057-S1058
Author(s):  
Y. Yamada ◽  
J. Maeda ◽  
T. Hoshino ◽  
T. Yokota ◽  
T. Uruno ◽  
...  

2020 ◽  
Vol 17 (4) ◽  
pp. 317-338
Author(s):  
Maria V Deligiorgi ◽  
Mihalis I Panayiotidis ◽  
Dimitrios T Trafalis

Considering the ‘differentiated thyroid carcinoma (DTC) epidemic’, the indolent nature of DTC imposes a treatment paradigm shift toward elimination of recurrence. Lymph node metastases in cervical compartments, encountered in 20–90% of DTC, are the main culprit of recurrent disease, affecting 5–30% of patients. Personalized risk-stratified cervical prophylactic lymph node dissection (PLND) at initial thyroidectomy in DTC with no clinical, sonographic or intraoperative evidence of lymph node metastases (clinically N0) has been advocated, though not unanimously. The present review dissects the controversy over PLND. Weighing the benefit yielded from PLND up against the PLND-related morbidity is so far hampered by the inconsistent profit yielded by PLND and the challenging patient selection. Advances in tailoring PLND are anticipated to empower optimal patient care.


2010 ◽  
Vol 2 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Gerard M Doherty ◽  
Travis J McKenzie ◽  
Joseph B Lillegard ◽  
Clive S Grant ◽  
Ian D Hay ◽  
...  

ABSTRACT The need for prophylactic central compartment lymph node dissection in patients with papillary thyroid carcinoma continues to be a subject of ongoing debate. Regional lymph node metastases are a common finding with papillary thyroid carcinoma, with an incidence as high as 50% or more. With the widespread use of high resolution ultrasound and sensitive thyroglobulin assays, lymph node metastases, not appreciated at the time of surgery, are showing up in the follow-up period, creating significant angst amongst patients, endocrinologists, and their surgeons. It was previously thought that lymph node metastases in papillary thyroid carcinoma had little bearing on survival, but this has more recently been challenged. Opponents of prophylactic central compartment node dissection cite high perioperative morbidity as a word of caution in performing prophylactic central neck dissections. The following review will look at the most up-to-date literature and best evidence for arriving at logical and sensible recommendations. This review will also look at specific definitions of what is a central compartment lymph node dissection. In the hands of experienced thyroid surgeons, prophylactic central compartment lymph node dissection, performed in a meticulous manner, can limit persistent or recurrent disease in the central compartment, and can diminish the need for routine administration of radioactive iodine, with acceptable perioperative morbidit


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