Use of reflux finding score and reflux symptom index for the management of laryngopharyngeal lesions: a pilot study

2021 ◽  
Author(s):  
Jacopo COLOMBINI ◽  
Massimo SPADOLA BISETTI ◽  
Roberto ALBERA ◽  
Davide G. RIBALDONE ◽  
Giorgio M. SARACCO ◽  
...  
Keyword(s):  
Pilot Study ◽  
Reflux Symptom ◽  
Reflux Finding Score ◽  
Reflux Symptom Index ◽  
Symptom Index

scholarly journals Correlation between reflux symptom index and reflux finding score in patients with laryngopharyngeal reflux: Our experience

2016 ◽  
Vol 3 ◽  
pp. 13-17
Author(s):  
Deepthi Satish ◽  
H. C. Badari Datta ◽  
B. V. Manjula ◽  
Brinda A. Poojari ◽  
Bhaskar Reddy Molluru
Keyword(s):  
Laryngopharyngeal Reflux ◽  
Reflux Symptom ◽  
Reflux Finding Score ◽  
Reflux Symptom Index ◽  
Symptom Index

Role of Reflux Symptom Index and Reflux Finding Score in Evaluation of Treatment Outcome in Patients with Laryngopharyngeal Reflux

2017 ◽  
Vol 7 (2) ◽  
pp. 39-43 ◽  
Author(s):  
Anuja Bhargava ◽  
Prasoon Varshney ◽  
Shikhar Saxena ◽  
Mohammad Shakeel ◽  
Amit P Srivastava ◽  
...  
Keyword(s):  
Treatment Outcome ◽  
Laryngopharyngeal Reflux ◽  
Reflux Symptom ◽  
Reflux Finding Score ◽  
Reflux Symptom Index ◽  
Symptom Index

Empirical treatment with pantoprazole as a diagnostic tool for symptomatic adult laryngopharyngeal reflux

2011 ◽  
Vol 125 (5) ◽  
pp. 502-508 ◽  
Author(s):  
M Masaany ◽  
M B Marina ◽  
W P Sharifa Ezat ◽  
A Sani
Keyword(s):  
Predictive Value ◽  
Laryngopharyngeal Reflux ◽  
Ph Monitoring ◽  
Reflux Symptom ◽  
Empirical Treatment ◽  
Double Blind Study ◽  
Reflux Finding Score ◽  
Reflux Symptom Index ◽  
Double Blind ◽  
Symptom Index

AbstractObjective:To determine the sensitivity and specificity of intensive empirical treatment with pantoprazole in diagnosing laryngopharyngeal reflux in adults.Study design:This was a prospective, double-blind study.Subjects and methods:Fifty-five patients with either a Reflux Symptom Index of more than 13 or a Reflux Finding Score of more than 7 were enrolled. All patients underwent 24-hour, double-probe pH monitoring before commencing pantoprazole 40 mg twice daily; both investigators and patients were blinded to pH monitoring results. The Reflux Symptom Index and Reflux Finding Score were reassessed during the second, third and fourth month of follow up.Results:The sensitivity of empirical pantoprazole treatment in diagnosing laryngopharyngeal reflux was 92.5 per cent. The specificity was 14.2 per cent, the positive predictive value 86 per cent and the negative predictive value 25 per cent. There was significant reduction in the total Reflux Symptom Index and Reflux Finding Score after the second, third and fourth month of treatment. There was no correlation between laryngopharyngeal reflux and body mass index.Conclusion:Our results suggest that intensive empirical treatment with proton pump inhibitors is effective in diagnosing laryngopharyngeal reflux.

Can the Reflux Finding Score and Reflux Symptom Index Be Used to Evaluate the Severity of Esophagitis in Children?

2019 ◽  
Author(s):  
Meltem Korkut Ugras ◽  
Muzeyyen Dogan ◽  
D. Yavuz Selim Pata ◽  
Ferda Ozkan
Keyword(s):  
Reflux Symptom ◽  
Reflux Finding Score ◽  
Reflux Symptom Index ◽  
Symptom Index

scholarly journals The application of 24-hour pharyngeal pH-monitoring and Reflux Finding Score and Reflux Symptom Index questionnaires in the diagnostics of laryngopharyngeal reflux

2019 ◽  
Vol 14 (4) ◽  
pp. 274-282
Author(s):  
Elżbieta Włodarczyk ◽  
Beata Miaśkiewicz ◽  
Danuta Raj-Koziak ◽  
Agata Szkiełkowska ◽  
Piotr Skarżyński ◽  
...  
Keyword(s):  
Laryngopharyngeal Reflux ◽  
Ph Monitoring ◽  
Reflux Symptom ◽  
Reflux Finding Score ◽  
Reflux Symptom Index ◽  
Symptom Index

Can the Reflux Symptom Index Score Predict the Reflux Finding Score?

2011 ◽  
Vol 145 (2_suppl) ◽  
pp. P78-P79
Author(s):  
Kristin K. Marcum ◽  
Catherine R. Lintzenich ◽  
Susan G. Butler ◽  
S. Carter Wright
Keyword(s):  
Index Score ◽  
Reflux Symptom ◽  
Reflux Finding Score ◽  
Reflux Symptom Index ◽  
Symptom Index

Association between Laryngeal Pepsin Levels and the Presence of Vocal Fold Polyps

2016 ◽  
Vol 156 (1) ◽  
pp. 144-151 ◽  
Author(s):  
Lu Wang ◽  
Jia-Jie Tan ◽  
Ting Wu ◽  
Rui Zhang ◽  
Jia-Nuan Wu ◽  
...  
Keyword(s):  
Vocal Fold ◽  
Laryngopharyngeal Reflux ◽  
Ph Monitoring ◽  
Reflux Symptom ◽  
Healthy Controls ◽  
Reflux Finding Score ◽  
Reflux Symptom Index ◽  
Symptom Index ◽  
Predictive Values ◽  
Laryngeal Mucosa

Objective To determine whether pepsin, the main component of refluxed gastric contents, is significantly associated with vocal fold polyps and to evaluate the diagnostic value of pepsin in vocal fold polyps’ tissues. Study Design Cross-sectional study. Setting Nanfang Hospital of Southern Medical University. Subjects and Methods The study included 32 patients with vocal fold polyps and 16 healthy controls between 2011 and 2012. Reflux symptom index and reflux finding score assessments, 24-hour combined multichannel intraluminal impedance and pH monitoring, and biopsy of the vocal fold polyp tissues or posterior laryngeal mucosa (healthy controls) for immunohistochemical pepsin staining were performed. Results The expression of pepsin was significantly higher in patients with vocal fold polyps than in controls (28/32, 75% vs 5/16, 31.25%; P < .001). The pepsin levels were significantly positively correlated with upright position pharyngeal acid reflux and esophageal reflux parameters adjusted by age. Based on pepsin staining data, the sensitivity and negative predictive values of 24-hour pH monitoring, the reflux symptom index, and the reflux finding score were 70% to 84.62%, whereas their specificity and positive predictive values were relatively low (20%-31.58%). Conclusion Pepsin reflux may be a risk factor for vocal fold polyps formation. In addition, pepsin immunohistochemical analysis of polyp biopsy samples appears to be a more sensitive and effective test for diagnosing laryngopharyngeal reflux than the reflux symptom index, the reflux finding score, and 24-hour pH monitoring in a clinical setting.

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